DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lapsyn and iglr-1

DIOPT Version :9

Sequence 1:	NP_611561.1	Gene:	Lapsyn / 37418	FlyBaseID:	FBgn0034602	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_510491.2	Gene:	iglr-1 / 184720	WormBaseID:	WBGene00008977	Length:	695	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	59/228 - (25%)
Similarity:	90/228 - (39%)	Gaps:	68/228 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 HIDKLLRIRCYDLDLKEVPQNL---KSSVEVLDLSHNRIRKLKTSSFQRYTDIKFLMLYDNMILS 96
            ||..:.|:...:..:|.:..::   ..::::||||.|.:.:|.||.|.....::.|:|.:|.|..
Worm   148 HIRSIQRVILRNNQIKSIGVHVFRYMPTLKMLDLSGNNMTRLVTSDFTSAVSLRELILRENKIEL 212

  Fly    97 VEVGTFEPLTSLQEIDLSNNGLTTIPLELFQLPRLRNLYIDSNELTSLNLQALEKPIRAPLEYLN 161
            :|..|.||:..|:.:|||.|.|:.:.||..|  ..|:|:
Worm   213 IETDTTEPMQQLETLDLSGNLLSEVRLEAQQ--NFRHLF-------------------------- 249

  Fly   162 VAGCELQELPDLGILPKLWQLNASMNPLQNFRIDSLANMCHLQVIDLTKSQLSQCGCQQVTNHLM 226
                               .||.|.||||..|..      .||:.||...||..|....|.
Worm   250 -------------------SLNLSCNPLQIIREG------FLQLPDLQVLQLDNCNISVVE---- 285

  Fly   227 MLGASPKFVPV-CLEALDIRECPLPYNRTIHSP 258
             .||   ||.: .|.::||::.|   |....||
Worm   286 -AGA---FVSLPRLHSMDIKDNP---NLAYFSP 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lapsyn	NP_611561.1	leucine-rich repeat	39..59	CDD:275380	2/22 (9%)
		LRR_8	58..118	CDD:290566	22/59 (37%)
		leucine-rich repeat	60..83	CDD:275380	9/22 (41%)
		leucine-rich repeat	84..107	CDD:275380	8/22 (36%)
		LRR_RI	<94..>249	CDD:238064	39/155 (25%)
		LRR_8	106..167	CDD:290566	11/60 (18%)
		LRR_4	106..145	CDD:289563	11/38 (29%)
		leucine-rich repeat	108..130	CDD:275380	9/21 (43%)
		leucine-rich repeat	131..154	CDD:275380	2/22 (9%)
		leucine-rich repeat	157..178	CDD:275380	0/20 (0%)
		leucine-rich repeat	179..202	CDD:275380	8/22 (36%)
iglr-1	NP_510491.2	LRR	<104..325	CDD:227223	59/228 (26%)
		leucine-rich repeat	106..128	CDD:275380
		leucine-rich repeat	129..151	CDD:275380	2/2 (100%)
		leucine-rich repeat	152..175	CDD:275380	2/22 (9%)
		leucine-rich repeat	176..199	CDD:275380	9/22 (41%)
		leucine-rich repeat	200..223	CDD:275380	8/22 (36%)
		leucine-rich repeat	224..247	CDD:275380	9/24 (38%)
		leucine-rich repeat	248..270	CDD:275380	11/72 (15%)
		leucine-rich repeat	271..294	CDD:275380	9/30 (30%)
		leucine-rich repeat	295..316	CDD:275380	7/20 (35%)
		leucine-rich repeat	320..343	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000