Protein Alignment tud and tdrd7

DIOPT Version :10

• Sequence 1: NP_476773.1
• Gene: tud / 37417
• FlyBaseID: FBgn0003891
• Length: 2515
• Species: Drosophila melanogaster
• Sequence 2: NP_001011355.2
• Gene: tdrd7 / 496822
• XenbaseID: XB-GENE-944683
• Length: 1088
• Species: Xenopus tropicalis
• Alignment Length: 1251
• Identity: 251/1251 - (20%)
• Similarity: 422/1251 - (33%)
• Gaps: 430/1251 - (34%)

  Fly  1465 ILENNQSVIDL--LKAE------KLVPGKDLDY-------------MRKQMEK-GKSRTYEYI-- 1505
            :|:.|::.:.|  |:||      :.:|.||:.:             :|.::.: |:...|..:
 Frog    16 VLQANKNGVPLSKLQAEYKSFTGEPIPFKDMGFHALDAYLKSIPSVVRIEVSRVGEVICYAVVCK 80

  Fly  1506 ETVDLTLDEEEDKGRKETVSKSGSANASPKKK-----QHNDKDREPKKSKPAEPARTVAPQPVAL 1565
            ||..:.......:..|:  ...|..|...:.|     .|..|    .|:...:|..| .||...:
 Frog    81 ETARIAALVAHQRSSKK--KSGGQVNCQMRLKYTAPVSHFGK----PKATLRQPGFT-PPQEKII 138

  Fly  1566 KTPSPVPA--------------EPAPVPKPATPVPEVVEVPEI---------------------N 1595
            :.|.|..|              .|.|:|:.....|..:.:|.|                     |
 Frog   139 RKPVPTSAWGKGNTFGSRTFEYSPPPIPQLFGIAPIQMHLPNINRPERKVTLPPRFQREVNSFLN 203

  Fly  1596 PT-VREAAAESKQA-----PAQEDPYKDLDCVVLSHCDNPAQFYVHPIDQLSKLNQLHENLQIVS 1654
            || :.::.|...|:     |....|..||..:.               :.|.:|...|.|...:|
 Frog   204 PTPMTDSNANHTQSLKSVVPGSGQPRCDLSVIQ---------------NNLKELLNKHSNGLWLS 253

  Fly  1655 PSLPQLMNVVNGADC-VSMYSVDKCWYRAKIIDAELMVLLFIDYGNTDCVSDATDIKESMWSHIE 1718
             .||||.......|. ..|......|...      .||...:..|:|:.|..:|.||:
 Frog   254 -KLPQLYKETYKQDLGGEMLKQVPSWTHI------CMVQKLVTMGHTEMVLYSTAIKQ------- 304

  Fly  1719 PFCLPCALPIRPKGTADWVDAANGIFNESYSKVPRLEYLTQGDHYTTSYVNMYIDGEDVAKKLIA 1783
                       |..|.:..:.:|   |::...||                   :|....:..|.:
 Frog   305 -----------PSFTKNVQNHSN---NQAKPNVP-------------------VDSTPSSPPLQS 336

  Fly  1784 DGFARPLEYLASGCSCYISHVNGICDFFIQLERDSKALELIELYLRKKDTLKPLEGFEKGLIVAA 1848
            .|                           .:.:|       ||   |:...|.|..:..|
 Frog   337 SG---------------------------NIPKD-------EL---KQKISKVLTKYSNG----- 359

  Fly  1849 LFEDDELWYRAQLQKELPDSRYEVLFIDYGNTSTTSKCLMLSEEIASLPSLSKKCSLQLPDAYIS 1913
                  |||.|     || ..:|.:|..           .|..|:.:|.||:..|::.|    ||
 Frog   360 ------LWYHA-----LP-KVFEDMFKQ-----------KLPTEVLNLDSLTDICTVDL----IS 397

  Fly  1914 WSPEAE---AKFAELTGEGELVFTTQLLKPGQDHVTIDLLLDGENIIDRLLPLCQRKE------- 1968
            ..|...   ||.||...:..        .|..::.....|.|.|:   .|||  :..|
 Frog   398 EEPFKAILYAKSAERANQNS--------NPSVNNNIPQKLQDRES---PLLP--EEPEMNMTPPP 449

  Fly  1969 ---PKEASKESLAV----TTKAIITHVENTSRIYLQFSE--KDSLMDIICEKLNGSKLQPKTEKA 2024
               |.|||...|.|    |...:|.::   .|.|....|  :|.:.| .|.|.:.:|:    ...
 Frog   450 LVIPSEASPSVLVVELSSTNDVVIRYI---GRDYSAAQEHMEDEMKD-FCSKSSTAKI----GFL 506

  Fly  2025 AVDDMCVVQFADDLEFYRSRILEVLEDDQYKVILIDYGNTTVVD--KLYELPQEFTLIKPVAEIC 2087
            .|..:...:..:|: :.|::| ..:|..:.||..:|||.:.:||  |:.:|.::|..:...|..|
 Frog   507 RVGQLVAAKAEEDV-WLRAQI-SAIEGKKVKVCYVDYGFSEIVDITKVCKLGKQFYTLPFQATKC 569

  Fly  2088 SM-------EPSAIFEKNKALTLTTFDALLDSCKGVVAVEFVNKSASPPVVRLTTKDKRSLKIYE 2145
            .:       :.|.|.   |||.       |.:|..::|||.:.||..|.||...|.....:.|..
 Frog   570 RLAGLEAFCDDSIII---KALE-------LKACGKILAVEILEKSEKPLVVLYDTSGDDDININA 624

  Fly  2146 H-LQKLVQAELKLIQKRNEN-SECIISYGNSPKSFYVQMKHNSADLDLIVKTLQSLKKEKLKKLI 2208
            . |::|....|.|..|.|.: |..|::...|..:.:.|:.  |..|..:.:|||.:..|...|.:
 Frog   625 ACLKELCDRSLSLQLKANSSFSNVIVTNVCSDGTLFCQLP--SKGLAKLYETLQKVDSEFQSKQV 687

  Fly  2209 DPTTN-------SNGVCYSQEDACYYRCSIKSVLDPSQGFEVFLLDYGN--TLVVPEVWQLP--- 2261
              |::       ...:|.......:.|..|.|| ..|:..:|..||.|.  ::.|.|:.::|
 Frog   688 --TSHLYVSLPFCGKICLYHYKGKWARVEITSV-HSSRALDVQFLDSGTIASVKVSELKEIPPPL 749

  Fly  2262 -QEIEPIPSLALHCQLSKIPM-----------------------DVSDEKLEEAFAALLEQHFGE 2302
             :::..||..||.|.|:.:|:                       .:...|::||      .:...
 Frog   750 LRDLISIPPQALRCCLADLPLRIGMWTPDAVLWLRNTVLNCLECSIRVVKVDEA------TNMVH 808

  Fly  2303 LYEITTQPNEDETKPL-----IAELRINYKD-FVQELVSTVT-----GVQKPLEAEL-------- 2348
            :|..|:....|..:.:     ..||..:.|| |:....||:.     |.|   .:||
 Frog   809 IYLFTSNNFPDLERSINRQITNEELWKHQKDVFLNLSASTLESSRGGGAQ---ASELSPPGLCKD 870

  Fly  2349 HNCVVVQFDGPMSFYVQMESDVPA---------------------------------------LE 2374
            |...|.:.|      :|..|.||:                                       ||
 Frog   871 HTSAVKKPD------MQQSSSVPSFNMPPPLPLPRPGEHMDVFVSVACHPGHFVCQPWQELHKLE 929

  Fly  2375 QMTDKLL---DAEQDLPAFSDLKEGALCVAQFPEDEVFYRAQIRKVLDDGKCEVHFIDFGNNAVT 2436
            .:.:::|   ...::.|.  .|::..|..|:.  :..:||..::.:|.:|...|:.:|:|.:.:.
 Frog   930 VVMEEMLLHYSTTEEKPV--ALEKNKLYAAKV--ENKWYRVLVKGILTNGLVSVYELDYGRHELV 990

  Fly  2437 ---------QQFRQLP-----EELAKPARYSRHCELDASTI------SKCDAALLQS-------- 2473
                     ::|.|||     .:||..:  ..|...:||.:      .|...||:|:
 Frog   991 SCRKVQPLIEKFMQLPFQAITSQLAGVS--CEHWSEEASIVFRNHVEKKPLVALVQTIHESTHPW 1053

  Fly  2474 -------FIDTRFSET 2482
                   .:||...:|
 Frog  1054 DRRAVAYIVDTSLPDT 1069

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tud	NP_476773.1	TUDOR	411..524	CDD:425754
		TUDOR	595..707	CDD:425754
		TUDOR	1016..1132	CDD:425754
		TUDOR	1309..1425	CDD:425754
		TUDOR	1620..1727	CDD:425754	20/107 (19%)
		TUDOR	1795..1906	CDD:425754	21/110 (19%)
		TUDOR	1980..2089	CDD:425754	27/112 (24%)
		TUDOR	2163..2277	CDD:425754	30/127 (24%)
		TUDOR	2347..2458	CDD:425754	30/174 (17%)
tdrd7	NP_001011355.2	LabA_like_C	7..93	CDD:472713	14/76 (18%)
		LabA_like_C	232..298	CDD:472713	18/87 (21%)
		LOTUS_3_TDRD7	342..407	CDD:193588	25/106 (24%)
		Tudor_SF	485..581	CDD:470623	23/102 (23%)
		Tudor_TDRD7_rpt2	645..784	CDD:410499	32/143 (22%)
		Tudor_TDRD7_rpt3	920..1010	CDD:410500	18/93 (19%)