Protein Alignment tud and rnf17

DIOPT Version :10

• Sequence 1: NP_476773.1
• Gene: tud / 37417
• FlyBaseID: FBgn0003891
• Length: 2515
• Species: Drosophila melanogaster
• Sequence 2: XP_021334643.1
• Gene: rnf17 / 334519
• ZFINID: ZDB-GENE-030131-6451
• Length: 1521
• Species: Danio rerio
• Alignment Length: 1498
• Identity: 298/1498 - (19%)
• Similarity: 499/1498 - (33%)
• Gaps: 445/1498 - (29%)

  Fly  1358 VGQICAVR------SSDGNWYRARISGKDSNAACFEVFYIDYGNTEEI---KRDDIKALD---AK 1410
            :|.|...|      .|...|...:.....|:||.         :|||.   |.|.:|.||   .|
Zfish    77 IGLIYTARMNTKKGHSGDKWKSQKFKSPPSSAAV---------HTEENAEGKPDVVKVLDEALTK 132

  Fly  1411 FYEHASGF-AVEINLPIGRPSNDTKLKARISEILEEKVVTIKSIEVRRSHLIADVILENNQSVID 1474
            ..|:.:.. .:...|..|......|.::||...::|.|...|||.::|..::...:     |.:|
Zfish   133 ATENLNQLDKLHQTLANGVHGQLRKERSRIIREIDEAVEKAKSILLKRRSMLVSTL-----SSVD 192

  Fly  1475 LLKAEKLVPGKDLDYMRKQMEKG--KSR---------TY----EYIETVDLTLDEE--------- 1515
            ||.:...:..|.::...|::...  |:|         ||    :.:||:.:.:|.|
Zfish   193 LLFSGGQMECKRIEERIKELRTAIQKARHVRQVPSLETYCDLEKILETLHIPVDLESYDMSSLTL 257

  Fly  1516 --------EDKGRKETV---------------------------------------SKSGSANAS 1533
                    :..|..|:|                                       |..|.|:|.
Zfish   258 RSGLSCHLQVDGFTESVKVFLKITDTDDNCIVEEITVEPFQHVVKSGVEMWDNSSQSVQGKADAI 322

  Fly  1534 PKKKQHNDKDREPKKSKPAEPARTVAPQPVALKTPSPVPAEPAPVPKPATPVPEVVEVPEINPTV 1598
            |:|..:..:..|       :......|:....:..:.:...        .||.|...:...|...
Zfish   323 PRKSNNTRRFME-------KMMEDTCPEIADTRVNAGLGRN--------LPVHEPRRMERYNKGY 372

  Fly  1599 REAAAESKQAPAQEDPYKDLDCVVLSHCDNPAQFYV-----HPIDQLSKLNQLHENLQIVSPSLP 1658
            |:......:.|....| |.:..||.:|..||..|||     |.:.|  ||.:..........|..
Zfish   373 RKQRRPQFEKPTNPQP-KLVQYVVTTHIVNPGHFYVRYMAEHKLGQ--KLTKKISEFCSGERSFF 434

  Fly  1659 QLMNVVNGADCVSMYSVDKCWYRAKII-----------------DAELMVLLFIDY--------- 1697
            ...:.:.....:.:...|..|.|.|:.                 :...:.:.|:||
Zfish   435 TFSDEITTGSLLFISWKDDMWCRVKVTELFQKECFQSVTKCLASEVSRLCVYFLDYGFFKGFSIP 499

  Fly  1698 ------GNTDCV---SDATDIKESMWSHIEPFCLPCAL-PIRPKGTADWVDAANGIFNESYSKVP 1752
                  |..:|:   ...|.|:.:.|:   |..:.|:| .|.|   ||.|...:...:|....|.
Zfish   500 SDGGLSGLNECLRRPDGITLIEMANWA---PLAIKCSLKDIIP---ADLVKGWSSEASEEMRNVL 558

  Fly  1753 RLEYLTQGDHYTTSYVNMYIDGE-------DVAKKLIAD-------------------------- 1784
            |.|           ...|.:.||       |:.|..:||
Zfish   559 RNE-----------TAEMQVFGEDGDALLVDLKKTSMADLKKNSMVSLREHLVFMELARFYCPVI 612

  Fly  1785 --GFARPLEY------LASGCSCYISHVNGICDFFIQLERDSK----ALELIELYLRKKDTLKPL 1837
              |.|..|.|      |....:..:||||...||::||..:::    ..:|.:.|.:.|.. ...
Zfish   613 TTGSAPLLFYPSVQPSLNVEVNAMVSHVNTPSDFYVQLVENTEYPLLHSKLQDCYNQPKSN-NEC 676

  Fly  1838 EGFEKGLIVAALFEDDELWYRAQLQKELPDSR-YEVLFIDYGNTSTTS-KCLM-LSEEIASLPSL 1899
            :.:...|..|.:...|:.|.|.|: ...|..| .||.|:|:|...|.| |.|. :.:|...||.:
Zfish   677 QVYCPSLSQACVAFHDQEWSRVQV-TGFPGGRMVEVRFVDFGYKRTLSVKDLRHIKDEFFVLPEM 740

  Fly  1900 SKKCSL-QLPDAYISWSPEAEAKFAELTGEGELVFTTQLLK---PGQDHVTIDLL-----LDGEN 1955
            :..|:| .:..:..:|:.||...|.||. ||:|:  |.:.|   |....|.:.|.     ..|.:
Zfish   741 ALWCNLNDVISSQETWANEACESFKELV-EGKLM--TVVAKKNVPSSKPVPVCLFEISDDCTGAS 802

  Fly  1956 IIDRL---------------------------------LPLCQRKEPKEASKE-----SLAVTTK 1982
            |.|.|                                 ||:..  .|..||:|     ||....|
Zfish   803 IGDELVKKGYAVYNKDTQVRDAQPLETTSWDPPFEEEALPVVM--TPSSASEELKPSLSLPSCLK 865

  Fly  1983 AI---ITHVENTSRIYLQFSEKDSLMDIICEKLNG--SKLQPKTEKAAVDDMCVVQFADDLEFYR 2042
            .|   :|||.:...|.:|..:.|:.:..|.:.|..  ||.:|:..:...:..|.|......|  |
Zfish   866 DIRVRVTHVTSPGNICVQLLQFDNQLKRIHDTLKNLFSKSEPQEMQWEAEMYCAVNNTGVWE--R 928

  Fly  2043 SRILEVLEDDQYKVILIDYGNTTV--VDKLYELPQEFTLIKPVAEICSMEPSAIFEKNKALTLTT 2105
            .::..|......:|:..|:|||..  ||.|..|..:  ||......|::............|.|.
Zfish   929 GQVCSVSTCGVAEVLRCDFGNTVKLHVDNLRPLHPD--LIGSFLLECNLSGVRPAGGRSTWTATA 991

  Fly  2106 FDALLDSCKGVVAVEFVNKSASPPVV----------------------RLTTKDKRSLKIYEHLQ 2148
            .|.:.....|.:|:..:.:.::.||:                      .|..|::::..::....
Zfish   992 CDFISHYLTGAMALMAIKEPSTRPVLVSLFCSNRAGQNVSFADFLISEGLALKERKAEMVFSEES 1056

  Fly  2149 KLVQAELKLI----------QKRNENSECIISYGNSP------------------KSFYVQMKHN 2185
            .||.....:|          ::.|...|.:.::...|                  :.....|.|.
Zfish  1057 VLVTEPQPVISPTQTPPTPSRRINPPPERVKTHSYPPPELPPCGHILMSISAVSEQGVIYAMTHQ 1121

  Fly  2186 S-ADLDLI-------VKTLQSLKKEKLKKLIDPTTNSNGVCYSQEDACYYRCSIKSVLDPSQGFE 2242
            : .:.|.:       :|||...|....|.::       |......|..:||..::.|:  ....:
Zfish  1122 AVCEFDRLRERLQQHIKTLPRQKNYNWKGVL-------GCAVMGTDMFWYRGQVQEVI--GGHVK 1177

  Fly  2243 VFLLDYGNTLVVPEVWQLPQEI-EPIPSLALHCQLSKI--------------------------- 2279
            |..:|.|....:|.....|..: |.:|.|.:.||::.:
Zfish  1178 VRYVDQGLVESIPVCHVYPMVLCEDVPQLCVPCQINGVLPIGKGWQWDAVVLMKELLLGRSVNVQ 1242

  Fly  2280 ----PMD----VSDEKLEE--AFAALLEQHFGELYEITTQPNED-ETKPLIAEL---RINYKDFV 2330
                |.|    |:.|.:.:  |.:.::..|....::......|| ..||.:.:|   .:|.:...
Zfish  1243 IMEHPKDPCGCVTVEIMVDGMALSKIMVHHQYATFDPAISSQEDYVVKPPMPDLDDWDLNTEGLE 1307

  Fly  2331 QELVSTVTGVQKPLEA------------------ELHNCVVVQFDGPMSFYVQMESDVPALEQMT 2377
            ::  ..|.||.|.|..                  |:..||:   |..:....|.||....|||:.
Zfish  1308 EQ--PPVLGVYKELHIPKERKHFPAKVKHIRTPNEVFLCVL---DKSLCKLEQDESMEETLEQVN 1367

  Fly  2378 DKLLDAEQDLPAFSDLKEGALCVAQFPEDEVFYRAQI---RKVLDDGKCEVHFIDFGNNAV--TQ 2437
            :.:    ::|...:|.....||:|:: .|..:|||:|   .:|....|..|..:|||::.:  ..
Zfish  1368 ENI----ENLSLLTDFPIECLCLAEY-SDGKYYRAKILGFSEVTPSVKLLVRHVDFGSDDIIPLH 1427

  Fly  2438 QFRQLPEEL--------------AKPARYSRHCELDASTISKCDAALLQSFIDTRFSETFQVEIL 2488
            :.||||..|              .||...|...|....::.....|::: .||....|...| :.
Zfish  1428 KLRQLPASLHHFPCAAVYVKLAGFKPTNVSSDLERIPYSLDWTMKAMME-MIDLLNGELTAV-VT 1490

  Fly  2489 ATK 2491
            |||
Zfish  1491 ATK 1493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tud	NP_476773.1	TUDOR	411..524	CDD:425754
		TUDOR	595..707	CDD:425754
		TUDOR	1016..1132	CDD:425754
		TUDOR	1309..1425	CDD:425754	18/79 (23%)
		TUDOR	1620..1727	CDD:425754	28/147 (19%)
		TUDOR	1795..1906	CDD:425754	33/118 (28%)
		TUDOR	1980..2089	CDD:425754	30/115 (26%)
		TUDOR	2163..2277	CDD:425754	25/140 (18%)
		TUDOR	2347..2458	CDD:425754	34/129 (26%)
rnf17	XP_021334643.1	RING_Ubox	6..66	CDD:473075
		TUDOR	394..534	CDD:425754	27/144 (19%)
		Tudor_SF	659..749	CDD:470623	25/91 (27%)
		Tudor_SF	894..965	CDD:470623	19/74 (26%)
		Tudor_TDRD4_rpt4	1148..1215	CDD:410488	16/75 (21%)
		Tudor_TDRD4_rpt5	1376..1481	CDD:410489	27/106 (25%)