Protein Alignment tud and ekl-1

DIOPT Version :10

• Sequence 1: NP_476773.1
• Gene: tud / 37417
• FlyBaseID: FBgn0003891
• Length: 2515
• Species: Drosophila melanogaster
• Sequence 2: NP_492009.1
• Gene: ekl-1 / 172444
• WormBaseID: WBGene00009052
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 689
• Identity: 117/689 - (16%)
• Similarity: 226/689 - (32%)
• Gaps: 235/689 - (34%)

  Fly  1356 FDVGQICAVRSSDGNWYRARISGKDSNAACFEVFYIDYGNTEEIKRDDIKALDAKFYEHASGFAV 1420
            |.:|......:.:..:.|.||.....|....:||:||......::.:.:..|| :.|.:....|:
 Worm    94 FKIGDYALAPTDERVYRRCRIVDVCRNNELLKVFFIDDAVIAWVQPECLGELD-QHYMYYPWQAI 157

  Fly  1421 EINLPIGRPSNDTKLKA----------RISEILEEKVVTIKSIEVRRSHLIADVILENNQS---V 1472
            ::::....|:.|.....          ::|::||:       ..:.|..::...::.|:.:   .
 Worm   158 QVSMFGATPTVDVNRSTEQLWSPIICDQLSKVLEQ-------FFILRVEVVLSTVVFNDYAKPIP 215

  Fly  1473 IDLLKAEKLVPGKDLDYMRKQMEKGKSRTYEYIETVDLTLDEEEDKGRKETVSKSGSANASPKKK 1537
            ::|...|..:..|  |.:|:.:|.|.  ..|..|.|.::..|..|....:....:
 Worm   216 VNLFGIEADIDEK--DQIRRAIEIGP--ILERQEPVGISFPEFFDAAYHQVFEVA---------- 266

  Fly  1538 QHNDKDREPKKSKPAEPARTVAPQPVALKTPSPVPAEPAPVPKPATPVPEVVEVPEINPTVREAA 1602
                 :||...::..|..|:.                  |.....|.:.|.....|     :|.|
 Worm   267 -----ERETIPNEALEIHRSF------------------PTDWKKTSISEDQMKEE-----KEKA 303

  Fly  1603 AESKQAPAQEDPYKDLDCVVLSHCDNPAQFYVHPIDQLSKLNQLHENLQIV--SPSLPQLMNVVN 1665
            ..||.:...|..:.|.|         |.|   :.|:.|| ::||.|..:..  |...|.:|..|.
 Worm   304 LFSKNSLIPEMEHSDWD---------PRQ---NSIEMLS-IDQLEEKFKFPYDSDVAPAIMLAVE 355

  Fly  1666 GADCVSMYSVDKCWYRAKII------DAELMVLLFIDYGNTDCVSDATDIKESMWSHIEPFCLPC 1724
            |....|.:.    ||...|:      :.|:::.           :|...:||     ::|
 Worm   356 GRCTKSPFE----WYARPIVKTGRNANGEMVIW-----------NDEEQLKE-----VDP----- 395

  Fly  1725 ALPIRPKGTADWVDAANGIFNESYSKVPRLEYLTQGDHYTTSYVNMYIDGEDVAKKLIADGFARP 1789
                     .||:...|.            :.|:..:...|.|.|
 Worm   396 ---------VDWMIYGND------------QLLSMAEQLDTYYSN-------------------- 419

  Fly  1790 LEYLASGCSCYISHVNGICDFFIQLERDSKALELIELYLRKKDTLKPLEGFEKGLIVAALFEDDE 1854
                                     .::.|.|:..|:...:|:        ::.:.......:::
 Worm   420 -------------------------PKNRKPLKAEEIQSMRKE--------KRDVFAVCAVNEEK 451

  Fly  1855 LWYRAQLQKEL---PDSRYEVLFIDYGN-----TSTTSK-----------CLMLS-EEIASLPSL 1899
            ..|..:.|:.|   .|:..||.|:|.|.     |.:..|           ||.|| ..|.|..|:
 Worm   452 AMYTGEWQRVLIVECDTFAEVRFLDSGGRDMVLTGSLYKIHRQHCRFPPMCLRLSMHGITSSESV 516

  Fly  1900 SKKCSLQLPDAYISWSPEAEAKFAELTGEGELVFTTQLLKPGQDHVTIDLLLDGENIIDRLLPLC 1964
            .:|           |:....::|.....|...:|           :.||      :|...:||..
 Worm   517 VRK-----------WTSAETSRFRTCLREDVPIF-----------INID------DIAPLILPPD 553

  Fly  1965 QRKEPK-EASKESLAVTTKAIITHVENTSRIYLQFSEKD 2002
            .:|:|: ..:|..|.|:.   :::::.:..:..:|::||
 Worm   554 DKKDPRAHMAKHVLMVSD---VSYMDESKSLLDRFTDKD 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tud	NP_476773.1	TUDOR	411..524	CDD:425754
		TUDOR	595..707	CDD:425754
		TUDOR	1016..1132	CDD:425754
		TUDOR	1309..1425	CDD:425754	14/68 (21%)
		TUDOR	1620..1727	CDD:425754	22/114 (19%)
		TUDOR	1795..1906	CDD:425754	23/130 (18%)
		TUDOR	1980..2089	CDD:425754	3/23 (13%)
		TUDOR	2163..2277	CDD:425754
		TUDOR	2347..2458	CDD:425754
ekl-1	NP_492009.1	TUDOR	55..163	CDD:425754	14/69 (20%)
		Tudor_SF	403..>491	CDD:470623	19/152 (13%)