DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tud and TDRD10

DIOPT Version :9

Sequence 1:	NP_476773.1	Gene:	tud / 37417	FlyBaseID:	FBgn0003891	Length:	2515	Species:	Drosophila melanogaster
Sequence 2:	XP_011507454.1	Gene:	TDRD10 / 126668	HGNCID:	25316	Length:	398	Species:	Homo sapiens

Alignment Length:	172	Identity:	41/172 - (23%)
Similarity:	63/172 - (36%)	Gaps:	51/172 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   414 VVISYVENGPYLFWVHLKSSDHDLSTMMGQIERTKLKALAQAPE-----------LGTACVARF- 466
            :|.|.|...|:.:.:|:..:.|       |..:.....||||.|           .||.|:|.:
Human   231 LVTSIVPKTPFFWAMHVTEALH-------QNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYH 288

  Fly   467 -SEDGH-------LYRAMVCAVYAQRYRVVYVDYG--------NSELLSASDLFQIPPELLEIKP 515
             .:.||       |.|....||      |:::|:|        :...|.:.|.:.|||   ..:|
Human   289 LGDYGHAWNRCWVLDRVDTWAV------VMFIDFGQLATIPVQSLRSLDSDDFWTIPP---LTQP 344

  Fly   516 FAFRFALAGTKEIEPIDDSMKRIFKKSAIYRNFELTVQAPES 557
            |.....:..:.|:      :.||. |..|.......|.||.|
Human   345 FMLEKDILSSYEV------VHRIL-KGKITGALNSAVTAPAS 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tud	NP_476773.1	DUF1421	198..>397	CDD:284607
		TUDOR	406..524	CDD:278965	32/137 (23%)
		TUDOR	454..510	CDD:197660	21/83 (25%)
		TUDOR	591..707	CDD:278965
		TUDOR	644..693	CDD:197660
		TUDOR	1012..1132	CDD:278965
		TUDOR	1062..1119	CDD:197660
		TUDOR	1309..1425	CDD:278965
		TUDOR	1354..1411	CDD:197660
		TUDOR	1614..1727	CDD:278965
		TUDOR	1666..1711	CDD:119391
		TUDOR	1791..1906	CDD:278965
		TUDOR	1843..1886	CDD:119391
		TUDOR	1975..2089	CDD:278965
		TUDOR	2028..2069	CDD:119391
		TUDOR	2159..2277	CDD:278965
		TUDOR	2210..2264	CDD:197660
		TUDOR	2345..2458	CDD:278965
		TUDOR	2396..2437	CDD:119391
TDRD10	XP_011507454.1	RRM	<7..>135	CDD:223796
		RRM_SF	77..134	CDD:302621
		TUDOR	<251..347	CDD:278965	27/111 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149516
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930