Protein Alignment tud and tdrd15

DIOPT Version :10

• Sequence 1: NP_476773.1
• Gene: tud / 37417
• FlyBaseID: FBgn0003891
• Length: 2515
• Species: Drosophila melanogaster
• Sequence 2: XP_031758847.1
• Gene: tdrd15 / 101731147
• XenbaseID: XB-GENE-6462376
• Length: 1916
• Species: Xenopus tropicalis
• Alignment Length: 1709
• Identity: 335/1709 - (19%)
• Similarity: 588/1709 - (34%)
• Gaps: 530/1709 - (31%)

  Fly  1003 LDKPYALQEMKTPSKEAASLSWWLSPFQFYIV------PKSVSAKYDNIMRDMREF-YRQKQHQP 1060
            :.||...:.:||.:|....||....|.....:      |.:|..|:........|| |...|::
 Frog     4 IQKPTKREILKTNTKMDVELSAKSLPNMALKILAVDCNPDNVIIKFQGKYNSESEFDYHILQNE- 67

  Fly  1061 LQL--KV------GSTVVVRQRKDNAILRATVTACNHMMRKYRVFCVDTGSLITVTSEDIWQLEQ 1117
            :||  ||      |...:|:.:...|..|..|  .|.:..|..||.:|.|:.:.|.|..|.....
 Frog    68 IQLVPKVRDGIGSGEFCLVQDKPFGAWQRGKV--LNKINEKSEVFLIDQGNTVNVDSTQIASASV 130

  Fly  1118 RFADPPCMAHRCSFHSVVTNYDPLYIVDRMETFVPVNAKVDCEFVSKEKSNQGSNTSSTCSYTVN 1182
            .....|..|....|..:                :|:..|...:.|:...|..|......
 Frog   131 ELFSLPPRAVNGIFSGI----------------LPLGDKWTPKAVNYFSSLVGLQVEGH------ 173

  Fly  1183 IFVNGASLRDMLVKAEFLTEVAPEIRVNLLAGQQIRGKFTSIRDMTSF--KVQFDYGNNVNFLCT 1245
               |.|.|.|.:...|..|.:...:.:||          ....|.|:|  ..:..|...:|:.|
 Frog   174 ---NQAVLLDQVTIFEVPTIITSAVELNL----------ARYIDSTTFCLLTEILYKATINYQC- 224

  Fly  1246 YDDAKFVKSNPNLARRFKEFYEGKSFAL-NVKNVCENNIVHLRPVMPLFMEDRRSFICPYPVVLS 1309
                   |..|:|.:: |..|...|.:| ::.:..:..:.||.|                .|.:.
 Frog   225 -------KQLPDLLQQ-KTLYLSSSHSLHDLLSSSQKILDHLLP----------------DVAIG 265

  Fly  1310 SFQALVVYTAKPY-RVY---VQPQAIVPSMQTLLDNMYEHYKAKGDSLKKFDVGQICAVRSSDGN 1370
            :.:.:.:..|..| |.|   :..:..:..:.||:.:.||..:.|.:|:.. :.|.:||.:..||.
 Frog   266 ATEKVKISAAVSYSRFYCHLLSWEKELGDLNTLMFSHYETIRIKQNSILD-NFGVLCAAKRKDGL 329

  Fly  1371 WYRARIS----GKDSNAACFEVFYIDYGNTEEIKRDDIKALDAKFYEHASGFAVEINLP-IGRPS 1430
            |:|..|.    ||.     .::::||.|..|.|....::.|..:|          :.|| :..|.
 Frog   330 WHRGVIETFLCGKK-----VQIWFIDIGCRETISSSFVQKLKTEF----------LTLPMMAVPC 379

  Fly  1431 NDTKLKARISEILEEKVVTIKSIEVRRSHLIADVILENNQSVIDLLKAEKLVPGKDLDYMRKQME 1495
            :...:..........::...|...:.:: :||.....||:        |:|.      |:..|
 Frog   380 SLISMNGHADYATNIQLTPFKQFLLGQA-VIATFEQFNNE--------ERLF------YITLQ-- 427

  Fly  1496 KGKSRTYEYIETVDLTLDEEEDKGRKETVSKSGSANASPKKKQHNDKDREPKKSKPAEPARTVAP 1560
                 |.||    ||                  :||.      |......|          ..:|
 Frog   428 -----TKEY----DL------------------NANC------HLTNQCVP----------VFSP 449

  Fly  1561 QPVALKTPSPVPAEPAP--VPKPATPVPEVVEVPEINPTVREAAAESKQAPAQEDPYKDLDCVVL 1623
            ........|.:|.:|:.  ||..|                      |.:|...:....|.|.|.:
 Frog   450 NCYRSLCDSTLPEKPSTFCVPDKA----------------------STEAVFHKTIQMDADSVHV 492

  Fly  1624 SHCD---NPAQFYVHPIDQL-----SKLNQLHENLQIVSPSLPQLMNVVNGADCVSMYSVDKCWY 1680
            .:.:   ||:.|::. .|:|     :.:.::.|......|:...|.:...|..|.::|..|:.:|
 Frog   493 GYVEYVLNPSNFWIR-TDELQNEFSAMMEKIAETYNPCGPTERVLKDPEPGDLCCALYYKDRHYY 556

  Fly  1681 RAKIID-AELMV-LLFIDYGNTDCVSDATDIKESM--WSHIEPFCLPCALPIRPKGTADWVDAAN 1741
            ||.:.| .:|.| :.|.|:|||:.| ...|:|..:  :..:....:.|:|.........||.:||
 Frog   557 RAIVTDILDLKVAVYFFDFGNTETV-PCYDVKTLLPEFEILPALAMCCSLAYAYPVEDVWVKSAN 620

  Fly  1742 GIF---------------NESYSKVPRLEYLTQGDH----------------------------- 1762
            ..|               ...|..:....||...::
 Frog   621 DFFKRMVSGKALLFHVLVKHKYKYIVDARYLEDSENSDIVMMMVKAGYAEYWKVNLNPSPVVTKI 685

  Fly  1763 -YTTSYVNMYIDGED-----VAKKLIADGFAR-----------PL---EYL---ASGCSCYISHV 1804
             .|..|.|..:..::     :||.::.:...|           |:   :||   .|..:...|||
 Frog   686 RSTGKYKNSKVVKQNKTRMTIAKHVLKNENERSRNQSPKTEVLPITFKQYLFKPGSVVNVKCSHV 750

  Fly  1805 NGICDFFIQLERDSKALELIELYLRKKDTLKPLEG--------FEKGLIVAAL-FEDDELWYRAQ 1860
            |...||:.||..::.||.|       :..:|.::.        ::.|.|...: ..|..::|||.
 Frog   751 NSPRDFWCQLLTETSALAL-------ESIMKDIQSYYSCCNDMYKHGQIACIVKCADSGIFYRAA 808

  Fly  1861 LQKELPDSRYEVLFIDYGNTSTTSKCLMLSE------EIASLPSLSKKCSLQ---LP-DAYISWS 1915
            :. .:.:...:::.:|||    .||..::|:      :..:|...:.:|||.   .| ..::||:
 Frog   809 VH-NVTEKAVDIILVDYG----YSKRALISDLREIKPQFLALEGQAFRCSLNSFLTPVRPHLSWT 868

  Fly  1916 PEAEAKFAELTGEGELVFTTQLLKPGQDHVTIDL--------------LLDGENIIDRLLPLCQ- 1965
            .||...|.:.....               ||.||              |.:..::..|.:.:||
 Frog   869 SEACRDFKDFVNSS---------------VTEDLKCTVHALFSMGTTDLFNAVSLEKRFVCVCQF 918

  Fly  1966 --RKEPKEASKESLAVTT-----------------KAIITHVENTSRIYLQFSEKDSLMDIICEK 2011
              .|.....|..|:.:.|                 :..||||.:|||.|.|.......::.:.::
 Frog   919 LLNKGHTAFSHASIPLITLRSFCYSDFNIKVGNLEQVYITHVYSTSRFYCQLVRNTEAIEALMKR 983

  Fly  2012 LN--GSKLQPKTEKAAVDDMCVVQFADDLEFYRSRILEVLEDDQYKVILIDYGNTTVVDKLYELP 2074
            ::  |.:| .:|:......:|:|::.:|..|||:....:.....:....:|:||:.:|.|...||
 Frog   984 VSDIGDQL-IQTDCTKESKLCIVKYFEDGHFYRALACPIESSLLFSAFFVDFGNSQMVTKKELLP 1047

  Fly  2075 QEFTLIKPVAEICSMEPSAIFE------KNKALTLTTFDALLDSCKGVVAVEFVNKSASPPVVRL 2133
            ...|    .|::.| ||....:      :|...|......|.::|.|:
 Frog  1048 IPDT----AADLLS-EPMQAIQFYLAGLENVVFTEEVIKWLDENCLGM----------------- 1090

  Fly  2134 TTKDKRSLKIYEHLQKLVQAELKLIQKRNENSECIISYGNSPKSFYVQMKHNSADLDLIVKTLQS 2198
                        .|..:|.|:           :|                    |..|:|    .
 Frog  1091 ------------QLNAVVLAK-----------DC--------------------DNQLVV----D 1108

  Fly  2199 LKKEKLKKLIDPTTNSNGVCYSQEDACYYRCSIKSVLD-PSQGFEVFLLDYGNTLVVPEVWQLPQ 2262
            |.||||                     :....:|.:|. |..|        .|.:::|   ||..
 Frog  1109 LYKEKL---------------------HINQKVKELLGYPPSG--------DNIVILP---QLKN 1141

  Fly  2263 EIEPIPSLALHCQLSKIPMDVSDEKLEEAFAALLEQHFGELYEITTQPNEDETKPLIA---ELRI 2324
            ||.|...           ..:|.::.|:..:.:|:      .|..:|.:|..|..|::   .|.:
 Frog  1142 EINPTSE-----------KGISKKQTEQLMSQMLK------CETPSQIDEVPTARLVSAFENLSV 1189

  Fly  2325 NYK--DFVQELV--------STVTGVQKPLE-AELHNCV----------VVQFDGPMSFYVQMES 2368
            |..  :.||.||        ..:|..:..:. ::|..|:          :...:.|.|||:|:..
 Frog  1190 NQMQCNSVQNLVHREGKVALDVITSPRTCITCSDLPECLIEPLSKDVGYISHINSPSSFYIQLSK 1254

  Fly  2369 DVPALEQMTDKLLDAEQDLPAFS--DLKEGALCVAQFPEDEVFYRAQIRKVLDDGKCEVHFIDFG 2431
            :..|:..:.::|........|.|  |.|:|.|..|::|:|..||||:|.::.:|...||.|||:|
 Frog  1255 NENAIVHLAEELNKEPLSFQALSARDCKKGMLVAAEYPDDLCFYRAEILEMKEDKSFEVKFIDYG 1319

  Fly  2432 NNAVTQQFRQLPEELAKPARYSRHCELDASTISKCDAALLQSFIDTRFSETFQVEILATKGTGTH 2496
            |.|.......||::.....::|....|                        |.:|.|.|:...:.
 Frog  1320 NTAYVSSLFLLPDKFLSVPKFSIAASL------------------------FGIEALKTREEWSR 1360

  Fly  2497 VVRLFYQSKNISEKLQECQ 2515
            .|..::..|...|.: :|:
 Frog  1361 DVTSYFSQKVNGESV-DCK 1378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tud	NP_476773.1	TUDOR	411..524	CDD:425754
		TUDOR	595..707	CDD:425754
		TUDOR	1016..1132	CDD:425754	31/130 (24%)
		TUDOR	1309..1425	CDD:425754	27/123 (22%)
		TUDOR	1620..1727	CDD:425754	28/118 (24%)
		TUDOR	1795..1906	CDD:425754	28/125 (22%)
		TUDOR	1980..2089	CDD:425754	28/127 (22%)
		TUDOR	2163..2277	CDD:425754	20/114 (18%)
		TUDOR	2347..2458	CDD:425754	35/122 (29%)
tdrd15	XP_031758847.1	Tudor_TDRD15_rpt1	33..178	CDD:410507	35/172 (20%)
		Tudor_TDRD15_rpt2	264..381	CDD:410508	30/132 (23%)
		Tudor_SF	485..625	CDD:470623	36/141 (26%)
		Tudor_SF	732..857	CDD:470623	31/136 (23%)
		Tudor_SF	942..1067	CDD:470623	30/130 (23%)
		Tudor_SF	1244..1349	CDD:470623	35/128 (27%)
		Tudor_TDRD15_rpt7	1462..1621	CDD:410513
		TUDOR	1670..1783	CDD:425754