Protein Alignment tud and tdrd6b

DIOPT Version :10

• Sequence 1: NP_476773.1
• Gene: tud / 37417
• FlyBaseID: FBgn0003891
• Length: 2515
• Species: Drosophila melanogaster
• Sequence 2: XP_068074939.2
• Gene: tdrd6b / 100536102
• ZFINID: ZDB-GENE-030131-6454
• Length: 1814
• Species: Danio rerio
• Alignment Length: 1849
• Identity: 372/1849 - (20%)
• Similarity: 656/1849 - (35%)
• Gaps: 585/1849 - (31%)

  Fly  1033 IVPKSVSAKY-DNIMR--DMREFY---------RQKQHQPLQLKVGSTVVVRQRKDNAILRATVT 1085
            :.|.:|..:: .|:.|  :.||.:         |::|| ..:.|.|...:|.:  |....||.:
Zfish    23 LTPHTVLVEFGGNLNRGQENREIWQQLKDIEVPRRRQH-AFEGKPGEICLVYE--DRTWHRARI- 83

  Fly  1086 ACNHMMRKYRVFCVDTGSLITVTSEDIWQLEQRFADPPCMAHRCSFHSVVTNYDPLYIVDRMETF 1150
             .:....:|.||.:|.|..:..|||.:.:..............|    ::||..||.    :|:.
Zfish    84 -ISETEYEYNVFLIDDGKSLWTTSEVLTKCPHNLCGLAPKVELC----ILTNVSPLC----LESG 139

  Fly  1151 VPVNAKVDCEFVSKEKSNQGSNTSSTCSYTVNIFVNGASLRDMLVKAEFLTEVAPEIRVNLLAGQ 1215
            ....|.   :|:   :|..|.|.|. |            ::|:::.:..:....|.|.
Zfish   140 WSAGAS---KFI---RSLCGKNISG-C------------VQDVIMPSRIILLDVPSIS------- 178

  Fly  1216 QIRGKFTSIRDMTSFKVQFDYGNNVNFLCTYDDAKFVKSNPNLARRFKEFYEGKSFALNVKNVCE 1280
                           |..:::|             |.|:.|  .:.||              :..
Zfish   179 ---------------KQMYEFG-------------FAKNTP--CKNFK--------------ILV 199

  Fly  1281 NNIVHLRPVMPLFMED--------------RRSFICPYPVVLSSFQALVVYT--AKPYRVYVQPQ 1329
            ...:|| |..|....|              .|.:...||.:......:|..|  ..|.::|.:..
Zfish   200 TYSLHL-PRSPSIQTDLLTTNGQQEHASNSDRLWQYLYPELSPGTIEIVTVTQVVHPLKIYCKLC 263

  Fly  1330 AIVPSMQTLLDNMYEHYKAKGDSLK-KFDV----GQICAVRSSDGNWYRARISGKDSNAACFEVF 1389
            .....::.|...:||||:   |:.. :..|    |..||.:.|||.|||:.:...|.:.. .:||
Zfish   264 VFSQELKKLSVQLYEHYE---DAFSAQIPVPLCDGSPCATKGSDGKWYRSVLQQNDISDV-VKVF 324

  Fly  1390 YIDYGNTEEIKRDDIKALDAKFYEHASGFAVEINLPI---GRPSN---DTKLKARISEILEEKVV 1448
            ::|||..:.:|..:|:.|.|:|:          :||:   |...:   |..:..|..:|...|.|
Zfish   325 HVDYGIGDFVKLSNIRPLSARFF----------HLPVVTYGCSLHGVIDKGVGWRTDQIDYLKSV 379

  Fly  1449 TIKSIEVRR------SHLIADVILENNQSV-IDLLKA---------EKLVPGKDLDYMRK----Q 1493
            .:..|.|.:      |..:..:.|..|.:| ::|...         ||:.....||.:.|    .
Zfish   380 ILDQILVGKFEHYSVSEGVYYITLYGNDNVNVNLTFGHKEHCLAVNEKMCGDPTLDTLNKVTYGN 444

  Fly  1494 MEKGKSRTYEYIETVDLTLDEEEDKGRKETVSKSGSANASPKKKQHNDKDREPKKSKPAEPARTV 1558
            |. |::.:.:.:.:..||    |.....|.|:..|     |.|.:.|   .:..|......|.|.
Zfish   445 MH-GRNDSLQSLHSAHLT----ECSSSVEDVNVVG-----PSKAEGN---LQSTKGGYTLNAATT 496

  Fly  1559 APQPVALKTPSPVPAEPAPVPKPATPVPEVVEVPEINPTVREAAAESKQAPAQEDPYKDLDCVVL 1623
            :|    |:|.:                  .|:||   |.::..|.....          :.||
Zfish   497 SP----LQTDA------------------YVDVP---PKIKVGAKMKLH----------ITCV-- 524

  Fly  1624 SHCDNPAQFYVHPIDQLSKLNQLHENLQIVSPSLPQL-MNVVNGADCVSMYSVDKCWYRAKIIDA 1687
               .:..|||.|.......:.::.:::|.:....||. .::.....|::.:| |..|:|.:|...
Zfish   525 ---QSVNQFYGHFAQNTDAVTKMTKDIQQLCRKRPQAKFSISPKMMCLAKFS-DGQWHRGQIESV 585

  Fly  1688 ELMVLL-FIDYGNTDCVSDATDIKESMWSHIEPF--------CLP----------CALPIRPKGT 1733
            ...:|: |:|||:. .|.|.:||.        ||        .||          .||| .|...
Zfish   586 HPKILVQFVDYGDL-VVVDKSDIL--------PFPPNANAIASLPIQAVQFELFNVALP-EPCEL 640

  Fly  1734 ADWVD--AANGIFN---------------------------ESYSKVPRLEYL-------TQGDH 1762
            .:|..  |.:.:||                           :.:||..|.|.:       |:|..
Zfish   641 NEWFKNYATDCMFNVVVKLNSSGKLSVEMYDDKTNLNLKIKDLWSKTKRNESINTKGIVKTRGFK 705

  Fly  1763 YTTSYV------NMYIDGEDVAKKLI--------------ADGFAR------------------- 1788
            .|:..:      |.:.......::.:              |.|::.
Zfish   706 ETSEGMEFREVRNSFSTTSQAHERTLKPVGQARTEQNFQSATGYSNATGNNRAWPNVLQQQVMAY 770

  Fly  1789 ------PLEYLASG--CSCYISHVNGICDFFIQLERDSKAL-------------EL-IELYLRKK 1831
                  ||..:..|  ...|:||.|...:||:||..|...:             :| :||.|.:.
Zfish   771 PKLTELPLRTIDVGYVSDVYVSHCNSPSNFFVQLTTDEDEIFSLIEKLNCTLISDLQVELNLLQS 835

  Fly  1832 DTLKPLEGFEKGLIVAALFEDDELWYRAQLQKELPDSRYEVLFIDYGN--TSTTSKCLMLSEEIA 1894
            |.|           |.|.:..|..:||| :.|...:...:|.|||:||  |...:|...|.::..
Zfish   836 DDL-----------VKAEYPADGAYYRA-VVKSKKNGMVQVQFIDFGNEVTLLPTKIKQLDKQFL 888

  Fly  1895 SLPSLSKKCSLQLPD----AYISWSPEAEAKFAELTGE-GELVFTTQLL-------------KPG 1941
            |.|.||.:|.|:  |    ....|:.|....|.|..|| ||.....:.:             :.|
Zfish   889 STPRLSIQCMLE--DGKRRGKRDWTQEEIMTFKEAAGENGEKKIQCKFIQEDANCWLVSLEHQEG 951

  Fly  1942 QDHVTIDLLLDGE-NIIDRLLPLCQRKEPKEASKESLAVTTKAIITHVENTSRIYLQFSEKDSL- 2004
            ...|..|...:.: :.|....||..:|......:     |.:|..:.:...:..:.||...:.|
Zfish   952 WFTVKSDAQSESQVHCIKNTQPLTFKKPAVTPGQ-----TVEAYASSIVGPNYFWCQFKNSEILD 1011

  Fly  2005 -MDIICEKLNGSK----LQPKTEKAAVDDMCVVQFADDLEFYRSRILEVLEDDQYKVILIDYGNT 2064
             :.::.:::..|.    :||  ::.....:|:.:|:|.| :||::::...|  :..|:.|||||.
Zfish  1012 KISLLAQEIGNSSHTKAIQP--DQLRQGGICLARFSDQL-WYRAQVINTHE--KVSVLFIDYGNE 1071

  Fly  2065 TVVD--KLYELPQEFTLIKPVAEICSM------------------------EPSAIFEKNKALT- 2102
            :.:|  .:..||.:.....|.|.:|.:                        ||..:..:|..:|
Zfish  1072 SEIDFNSIKALPTKLLESPPQAFLCQLQVLGSVEGTWSDSAADKFFEILVDEPLKVTVQNMVVTP 1136

  Fly  2103 ----LTTFDALLDSCK-----------------------------------GVVAVEFVNKSASP 2128
                ...|..|:: ||                                   ||...|.|.|:.:|
Zfish  1137 NPTMCPQFSVLVE-CKELIVNDLMKDFLSDPKPQVSSKGSMAKTNAGKDDFGVTNSEAVQKNKTP 1200

  Fly  2129 PVVRLTT------------------KDKRSLKIYEHLQKLVQAELKLIQKRNENSECIISYGNSP 2175
            .:...||                  .|..|::.:.....|.|   ::||. ...||..||:.|:.
Zfish  1201 NLNSSTTPSIDDVNNSAALTTGVNMMDPESMQSFPRSVDLPQ---RVIQP-GTMSEVYISHINNL 1261

  Fly  2176 KSFYVQMKHNSADLDLIVKTLQSLKKEKLKKLIDPTTNSNGVCYSQ---------EDACYYRCSI 2231
            :|||||:|.:...|..:.::|.|.:..:..::       :|:...|         ||..:||..:
Zfish  1262 RSFYVQLKEDENTLFSLTESLNSHQPSEKDEM-------HGLSVQQGSLVKAMFPEDDSWYRAVV 1319

  Fly  2232 KSVLDPSQGFEVFLLDYGNTLVVP--EVWQLPQEIEPIPSLALHCQLSKIPMDVSDEKLEEAFAA 2294
            |...:....|..| :|:||..:|.  ::.:|.:.:...|..::||..|          |.:.|..
Zfish  1320 KCAPENDMVFVEF-IDFGNEAMVSSLKICRLDEHLLSYPRFSIHCSYS----------LNDQFKG 1373

  Fly  2295 LLEQHF---------GE-------------LYEITTQPNE---DETKPLIAELRINYKDFVQELV 2334
            :.:|..         ||             .:|:|..|.|   |.......:|.:|....|.:.|
Zfish  1374 MKKQEILFKEVLGGAGENTLSCSFIKKDDIAWEVTMTPCEGTSDSFSKKWDQLDLNALSVVTKPV 1438

  Fly  2335 STVTG--VQKP-------LEAELHNCVVVQFDGPMSFYVQMESD--VPALEQMTDKLLDAEQDLP 2388
            .....  .:||       :|| ..:|:|    ||..|:.|..:.  :..:.|:..:..::.:..|
Zfish  1439 KETFNFLFKKPDVSLGQTIEA-FASCIV----GPDYFWCQFSNSEILDHITQVAQECGNSSETQP 1498

  Fly  2389 AFSD-LKEGALCVAQFPEDEVFYRAQIRKVLDDGKC----EVHFIDFGNNAVTQQ--FRQLPEEL 2446
            ...| |..|:.|:|:|.:|:::||||:.|     ||    .|.|:||||.:...:  .:.||.:|
Zfish  1499 ILLDNLDSGSPCLARFCDDQMWYRAQVIK-----KCTNTVSVLFVDFGNESEASEGSVKALPCDL 1558

  Fly  2447 AKPARYSRHCELDASTIS--KCDAALLQSF---------------IDTRF---SETFQVEILATK 2491
            .:....:..|.|:....|  ..|:....:|               ||...   |..:.|::.:::
Zfish  1559 LESPPQAFLCRLEGFNPSGGSWDSEATDNFYELLVDKPLKVSVQCIDDSVEPNSPPYYVKVESSQ 1623

  Fly  2492 GTGTHVVRLFYQS-----KNISEKLQECQ 2515
            .....::..|:.:     :|.:|.::.|:
Zfish  1624 SLVNELMAKFWSNCTHHDQNSAEVIESCE 1652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tud	NP_476773.1	TUDOR	411..524	CDD:425754
		TUDOR	595..707	CDD:425754
		TUDOR	1016..1132	CDD:425754	24/110 (22%)
		TUDOR	1309..1425	CDD:425754	31/122 (25%)
		TUDOR	1620..1727	CDD:425754	29/126 (23%)
		TUDOR	1795..1906	CDD:425754	37/128 (29%)
		TUDOR	1980..2089	CDD:425754	27/116 (23%)
		TUDOR	2163..2277	CDD:425754	31/124 (25%)
		TUDOR	2347..2458	CDD:425754	32/119 (27%)
tdrd6b	XP_068074939.2	None