Protein Alignment tud and tdrd1

DIOPT Version :10

• Sequence 1: NP_476773.1
• Gene: tud / 37417
• FlyBaseID: FBgn0003891
• Length: 2515
• Species: Drosophila melanogaster
• Sequence 2: XP_004919429.1
• Gene: tdrd1 / 100216261
• XenbaseID: XB-GENE-6455203
• Length: 1165
• Species: Xenopus tropicalis
• Alignment Length: 1134
• Identity: 244/1134 - (21%)
• Similarity: 398/1134 - (35%)
• Gaps: 333/1134 - (29%)

  Fly  1555 ARTVAPQPVALKTP----SPVPAEPAPVPK--PATPVPEVVEVPEINPTVREAAAESKQAPAQED 1613
            |.::..:|:|.|..    ||.......||:  .|:||..       :|...|...:...:..||.
 Frog   134 AHSIFCKPLAAKEQGACRSPTGGGEQIVPRRGEASPVGN-------SPKTEELVKKIMFSDLQES 191

  Fly  1614 PYKD--------LDCVVLSHCDNPAQFYVH-----PIDQLSKLNQLHENLQIVSPSLPQLMNVVN 1665
            ..::        ||.:      :|::|.:.     .:|.|.|::.|.:.:.....:|.:......
 Frog   192 GLREGKESQGFVLDFL------SPSKFNIQVCNTKSLDSLVKVSTLLKEIYTKPENLKKGYTPAI 250

  Fly  1666 GADCVSMYSVDKCWYRAKI--IDAELMV--LLFIDYGNTDCVSDATDIKESMWSHIE---PFCLP 1723
            |..||:.|:.|:.|||..:  :||::.:  :|::|||||:.||  .|..:.|...:|   |..:.
 Frog   251 GEVCVARYAQDQNWYRVMVHSLDAQMKMAQVLYLDYGNTEAVS--IDDVQQMHKDVELFPPSAIK 313

  Fly  1724 CALPIRPKGTADW-----VDAANGIFNESYS-KVPRLEYLTQGDHYTTSYVNMYIDGEDVAKKLI 1782
            |.|.........|     ||....:..:..: .|.|:|. .:...|... |.:...|:.|.|.|:
 Frog   314 CFLANIAAPPCGWTPECLVDVRKLLLGKKVTFTVLRIEQ-EEPPIYGVD-VTLPSSGDRVGKYLL 376

  Fly  1783 ADG--FARPLEYLASGCSCYISHVNGICD------------------------------------ 1809
            ..|  |:..::.....||   |..:.|.|
 Frog   377 DKGYCFSPEVKSKMKRCS---SETDSILDKAANPEETSTELPPTLKVVSVSAGDIFNAVITDIQT 438

  Fly  1810 ---FFI-QLERDSKALELIELYLRKKDTLKPLEGFE--KGLIVAALFEDDELWYRAQLQKELPDS 1868
               ||. ||:...:..||:|...:...|.....||.  .|.|.:|||.:|..||||.:...:.:.
 Frog   439 PSRFFCQQLQNGQQLAELMESMEKHYKTAPVSPGFSPIAGEICSALFTEDNRWYRATVLDRVSED 503

  Fly  1869 RYEVLFIDYGNTS--TTSKCLMLSEEIASLPSLSKKCSLQ-LPDAYISWSPEAEAKFAELTGEGE 1930
            ...|.::|:||..  ..|:...:...:.:.|..:.:|||: :..|..:|:.||..|.|.|.  ..
 Frog   504 SALVGYVDFGNVEHLPVSRLRPIPARMLAFPLQAIQCSLEGVRPASKTWTKEATTKMASLV--AN 566

  Fly  1931 LVFTTQLLKPGQDHVTIDLLLDG----ENIIDRLLPLCQRKEPKEA-------SKESLAVTTKAI 1984
            .:.|.:::...:..:.:: ||||    |..|.|.|.|......|||       |..:||.|...:
 Frog   567 KMITVRVITESEGSLMVE-LLDGSVNPELDIARQLILAGLAVDKEAGVGMDEGSSGALAGTGGEL 630

  Fly  1985 I----------THVE---------------NTSRIYLQF-SEKD--SLMDI------ICEKLNGS 2015
            :          |..|               :....:.|. :|||  ||.::      .|:|.:.:
 Frog   631 MDDSGAKPGQWTSAELPLGRAVDVSVCMLYSPGEFFCQLCNEKDAKSLTELNRSLGQHCQKGSAT 695

  Fly  2016 KLQPKTEKAAVDDMCVVQFADDLEFYRSRILEVLEDDQYKVILIDYGNT---------TVVDKLY 2071
            :..||..|     :|...|:.|..:||:.::.| |....||..:|||||         .:..:|.
 Frog   696 QYNPKAGK-----ICCAFFSGDGNWYRAMVMGV-EQKGTKVRFMDYGNTEELEAGELCDIPSQLL 754

  Fly  2072 ELPQE-----FTLIKPVAEICSMEPSAIFEKNKALTLTTFDALLDSCKGVVAVEFVNKSASPPVV 2131
            |||.:     .|.:||:.|....:....|:.:.|.......|:..:..| ..||.|...:...|.
 Frog   755 ELPFQAIRCSLTGVKPIGEKWDRDAIIAFQSSVAGVKLKAKAVGKNDNG-YRVELVASESGSSVS 818

  Fly  2132 RLTTKDKRSLKIYEHLQKLVQA--ELKLIQKRNENSECIISYGNSPKSFYVQMKHNSADLDLIVK 2194
            .....:|  :.:::..|:..:|  .....||....:|.|...|:..|.......|.....|
 Frog   819 EALIAEK--VAVHDTAQEAGEAGDSHPPRQKPTGRAENISMDGSGDKGPQSTKTHTPKVPD---- 877

  Fly  2195 TLQSLKKEKLKKLIDPTTNSNGVCYSQEDACYYRCSIKSVLDPSQGFEVFLLDYGNTLVVPEVWQ 2259
                 ::|.|:....|.        .:::||        |..|
 Frog   878 -----QRETLQASPAPP--------KEKEAC--------VRTP---------------------- 899

  Fly  2260 LPQEIEPIPSLALHCQLSKIPMDVSDEKLEEAFAALLEQHFGELYEITTQPNEDETKPLIAELRI 2324
             |:|..|          ||........|:|||..|
 Frog   900 -PREDSP----------SKTNGPPQGTKMEEAGVA------------------------------ 923

  Fly  2325 NYKDFVQELVSTVTGVQKPLEAELHNCVVVQFDGPMSFYV---QMESDVPALEQMTDKLL----- 2381
                      ...|.::.||. |....:|:....|..||.   :...||..|:|...::.
 Frog   924 ----------RCWTSIELPLH-EAAQALVLCVISPDLFYAFPKENRVDVGKLQQTMIEMAAYCSI 977

  Fly  2382 --DAEQDLPAFSDLKEGALCVAQFPEDEVFYRAQIRKVLDDGKCEVHFIDFGNN---------AV 2435
              |.:...||..|     .|.|:|..|..:|||.:... .:.:.||.:.|:||.         |:
 Frog   978 QSDCQNFRPAVGD-----ACCARFTGDGQWYRAIVLGT-SETEAEVAYADYGNTESLPYSSLVAI 1036

  Fly  2436 TQQFRQLPEELAK--------------PA--RYSRH----CELDASTISKCDAALLQSFIDTRFS 2480
            .:.|...|.::.|              ||  |..||    |:|..:      |..||:.:
 Frog  1037 KESFLDPPVQIIKCRLTGVKPLDAEWIPAATRLLRHILLGCQLTVT------AMALQAGV----- 1090

  Fly  2481 ETFQVEILATKGTGTHVVRLFYQSKNISE 2509
            .:..|||:  |.||.    |..|.|.|:|
 Frog  1091 HSVAVEIM--KETGA----LLVQDKLINE 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tud	NP_476773.1	TUDOR	411..524	CDD:425754
		TUDOR	595..707	CDD:425754
		TUDOR	1016..1132	CDD:425754
		TUDOR	1309..1425	CDD:425754
		TUDOR	1620..1727	CDD:425754	30/118 (25%)
		TUDOR	1795..1906	CDD:425754	33/154 (21%)
		TUDOR	1980..2089	CDD:425754	36/156 (23%)
		TUDOR	2163..2277	CDD:425754	16/113 (14%)
		TUDOR	2347..2458	CDD:425754	35/149 (23%)
tdrd1	XP_004919429.1	zf-MYND	103..139	CDD:460312	1/4 (25%)
		Tudor_TDRD1_rpt1	201..331	CDD:410479	34/137 (25%)
		Tudor_TDRD1_rpt2	450..531	CDD:410480	21/80 (26%)
		TUDOR	653..767	CDD:425754	29/119 (24%)
		Tudor_TDRD1_rpt4	939..1054	CDD:410482	28/120 (23%)