DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pu and gch1

DIOPT Version :9

Sequence 1:	NP_726038.1	Gene:	Pu / 37415	FlyBaseID:	FBgn0003162	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001129727.2	Gene:	gch1 / 100192219	ZFINID:	ZDB-GENE-070720-5	Length:	251	Species:	Danio rerio

Alignment Length:	186	Identity:	139/186 - (74%)
Similarity:	162/186 - (87%)	Gaps:	0/186 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 EALLPDMARSYRLLLGGLGENPDRQGLIKTPERAAKAMLYFTKGYDQSLEDVLNGAVFDEDHDEM 202
            |..||.:|.:|..:|.||||:|.||||:|||.|||.||.:|||||.:.:.||||.|:||||||||
Zfish    66 EMSLPSIAAAYTTILRGLGEDPQRQGLLKTPWRAATAMQFFTKGYQEKIIDVLNDAIFDEDHDEM 130

  Fly   203 VVVKDIEMFSMCEHHLVPFYGKVSIGYLPCNKILGLSKLARIVEIFSRRLQVQERLTKQIAVAVT 267
            |:||||:|||||||||||.:|:|.|||||..::||||||||||||:|||||||||||||||||:|
Zfish   131 VIVKDIDMFSMCEHHLVPIFGRVHIGYLPNKRVLGLSKLARIVEIYSRRLQVQERLTKQIAVAIT 195

  Fly   268 QAVQPAGVAVVVEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEFLNLVNS 323
            :|:|||||.||||..|||||||||||:||||||||||||||:|||||:|||.|:.|
Zfish   196 EALQPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTRDEFLTLIRS 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pu	NP_726038.1	GTP_cyclohydro1	141..323	CDD:238349	137/181 (76%)
gch1	NP_001129727.2	GTP_cyclohydro1	67..251	CDD:238349	137/183 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581486
Domainoid	1	1.000	279	1.000	Domainoid score	I1663
eggNOG	1	0.900	-	-		E1_COG0302
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H132
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2820
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D529046at33208
OrthoFinder	1	1.000	-	-		FOG0002669
OrthoInspector	1	1.000	-	-		otm26069
orthoMCL	1	0.900	-	-		OOG6_101153
Panther	1	1.100	-	-	O	PTHR11109
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2044
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.760