DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Xpd and AT1G79950

DIOPT Version :9

Sequence 1:	NP_726036.2	Gene:	Xpd / 37414	FlyBaseID:	FBgn0261850	Length:	769	Species:	Drosophila melanogaster
Sequence 2:	NP_178113.3	Gene:	AT1G79950 / 844335	AraportID:	AT1G79950	Length:	1040	Species:	Arabidopsis thaliana

Alignment Length:	809	Identity:	199/809 - (24%)
Similarity:	344/809 - (42%)	Gaps:	125/809 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SVDGLLVYFPYEYIYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMVEHPE-TV 67
            |:.|:.|.||:| .|..|..||..:..||..|.|.|||.|:|||||..||...:|:...... :.
plant    50 SIRGINVEFPFE-AYQSQIIYMDRVIESLQNKCHALLESPTGTGKTLCLLCATLAWRKSLGSFST 113

  Fly    68 RK-----------------------------LIYCSRTVPEIEKVIAELQNLMVYYERHCPNPPP 103
            ||                             ::|.|||..::.:||.||       :|....|..
plant   114 RKDRKNSAIPWSDSDEPLSQSGGGGGGAFPTIVYASRTHSQLRQVIKEL-------KRSSYRPKM 171

  Fly   104 FTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMDTETPICQYFEGFSLEGKES 168
               :||.||:.:|::.||:..| |||:...|..|...  |.:.:.:....:..|.:.....|.|
plant   172 ---VVLGSREQLCVNEEVNSLR-GKALTNACQYLCKK--RGKRQCNHFNRLPDYLKHNPHIGDE- 229

  Fly   169 TLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVF 233
              ||   .|:||...|:....|||::.|.......|:...|:||:.....:.:....: .|.::|
plant   230 --PV---DIEDLVNIGKDSGPCPYYITRELHKDVDIIFAPYNYLISNGYRKFLKVNWT-NSVLIF 288

  Fly   234 DEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQGLKDASVQ 298
            |||||::::|.||.|..:....:....:......:|....|:               .|.|.|:.
plant   289 DEAHNLESLCADSASFDLPSVLLSACISEAQECVQLAAARRD---------------SLNDVSIN 338

  Fly   299 RDTDMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYIKTRLRVHHVVQESPAGFLKDISS 363
            .:...||...:|....|...||  |...|...:....:|..:...|.:.|.......|.:::  :
plant   339 PENFAILKGLLLKLQELISKVP--IPKRDEGFTKPGPYIYEMLKSLNITHETAPKLIGTVEE--A 399

  Fly   364 KICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLITHFATLVSTYTKGFTIIIEPFDDKTPTV 428
            .:.:|.:..| .|....|.|..  |:|:     |.||  |....|.:...:.:.::..:..:..|
plant   400 AVFLEEEKQR-TATNAGSKLEI--IADM-----LKLI--FRENGSNHADVYRVHVQELEQNSTDV 454

  Fly   429 S----NPILHFSCLDSSIAMAPVFSR-FQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTLARP 488
            .    :..|.:.|....|.|..:..: ..::::|||||||||...:.|..|      |.:.|..|
plant   455 MKGKVSRTLSWWCFSPGITMLDIAQKGVGSIILTSGTLSPMDSLAQELKLD------FPIRLENP 513

  Fly   489 CLLPM------IVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLES 547
            .::..      :||.|.....::|.:..|:.....:..|..:|..::.||:|::.||.||..::|
plant   514 HVISSNQLWAGVVSTGPSGYVLNSSYRNRDVPEYKQELGNAIVNFSRVVPEGLLIFFPSYYLMDS 578

  Fly   548 VVASWYD------QGIVDTLLRYKLLFIETQDNAETSYALMNYVKACD--CGRGAVLLAVARGKV 604
            .:..|.:      ..:.:.:.:.|...||.:|::....|:.::.:...  ...|.|..||.||||
plant   579 CITFWKNGCYRNSMTVWERICKLKKPVIEPKDSSLFPAAMRDFSEKLQDRATSGVVFFAVCRGKV 643

  Fly   605 SEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRE-----------NDFLTFDAMR 658
            |||:||....||||::.|:||.......:|.:.::|.:|.|:.:           :.:.:.:|.|
plant   644 SEGLDFADGAGRAVVITGLPYARVTDPRVKLKREFLDEQSQLADVKLPRSTLLSGSMWYSQEAAR 708

  Fly   659 HAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQEHLVDSFCNLSTEEAVQLARRWLRR 723
            ...|.:||.:|.:.|||.:||.|.||.:..::|::..||:.::.   |.....|.:....|:.|.
plant   709 AVNQAIGRVIRHRHDYGAIIFCDDRFEQPSQQSKISLWIRPNVK---CYSRYGEVISDLARFFRT 770

  Fly   724 MAQPF------TREDQLGISLLTLAQLEN 746
            ....|      .:|:.:..:||.:..:|:
plant   771 ERSNFPARLVTEQENNIVSTLLPVESIED 799

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xpd	NP_726036.2	rad3	7..717	CDD:273169	191/769 (25%)
		DEXDc2	8..280	CDD:214693	80/301 (27%)
		HBB	270..413	CDD:284245	28/142 (20%)
		HELICc2	542..686	CDD:214694	46/162 (28%)
AT1G79950	NP_178113.3	rad3	56..762	CDD:273169	190/764 (25%)
AT1G79950	NP_178113.3	HN_RTEL1	928..1032	CDD:259826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186062at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820