DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Xpd and AT1G79890

DIOPT Version :9

Sequence 1:	NP_726036.2	Gene:	Xpd / 37414	FlyBaseID:	FBgn0261850	Length:	769	Species:	Drosophila melanogaster
Sequence 2:	NP_178107.1	Gene:	AT1G79890 / 844328	AraportID:	AT1G79890	Length:	882	Species:	Arabidopsis thaliana

Alignment Length:	908	Identity:	186/908 - (20%)
Similarity:	325/908 - (35%)	Gaps:	279/908 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FPYEYIYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMV--------------- 61
            |||: .|..|..:|..|.:.||..|..:||.|:||||:.:::...:.::.
plant    10 FPYK-PYSIQIDFMNALYQFLDKGGVSMLESPTGTGKSLSIICSALQWLTDRKEKRNSGLTEESH 73

  Fly    62 --------EHPETVR-------------------------------------------------- 68
                    :.|:.:|
plant    74 KVDGNDDEDEPDWMRNFTLNEADGANGDKSIKNTKSPFSLRKHAKEVFTEGEKADELNDQEFLLD 138

  Fly    69 ---------------------------------------------KLIYCSRTVPEIEKVIAELQ 88
                                                         |:.:||||..::.:.:.||:
plant   139 EYESQDESSPGGGNSKRKPARGFDSSSSEDEEDENDCSDDEQGGFKVFFCSRTHSQLSQFVKELR 203

  Fly    89 NLMVYYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGL---TASYIRERHEMDT 150
            . .|:.::       ...:.|.||||:||:.:|.|......::.:|..|   ..|.:.::..:..
plant   204 K-TVFAKK-------LKVVCLGSRKNLCINEDVLKLGNVTRINERCLDLQKKKISQVSKKKNLGA 260

  Fly   151 ETPI--------CQYFEGFSL--EGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIV 205
            ...|        |.......|  |.|..:.......|:||.:.||....|||:.:|.....|.:|
plant   261 NVRIVRTKASCRCPMLRKHKLQREFKAESFQQEAMDIEDLVQLGREMRTCPYYGSRRMAPAADLV 325

  Fly   206 VYSYHYLLDPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLV 270
            :..|..||.....:.:...: :.|.|:.|||||:.:..:.....|:   ||.:.
plant   326 ILPYQSLLSKSSRESLGLSL-KNSVVIIDEAHNLADTLLSMHDAKL---TVSQL----------- 375

  Fly   271 QDIREEDTNRLNEEYQRMVQGLKDASVQRDTDMIL------ANPVLPNDVLTEVVPG-------- 321
                 ||.:...|.|....|.|..|..:|...::|      ..|:..:..|:.|..|
plant   376 -----EDIHCSIESYLGRFQNLLGAGNRRYIQIMLILTRAFLKPLASDRNLSSVNVGLDTENPSK 435

  Fly   322 ------------------NIRNADHFLSFLRRFIEYIKTRLRVHHVVQESPAGFLKDISSKICIE 368
                              ||.|.:     |.:.:.|||....:|.|     :|:
plant   436 SKPCGACSMAIYDFLFSLNIDNIN-----LVKLLAYIKESNIIHKV-----SGY----------- 479

  Fly   369 RKPLRFCAERLSSLLRT-----LEISDLTEYGALTLITHFATLVSTYTKG---FTIIIEPFDDKT 425
                   .||::::|:.     .|:|.||.:.|      |:.::...|..   ..|||......|
plant   480 -------GERVAAMLQKDPVAHEEMSKLTSFRA------FSDMLVALTNNNGDGRIIISRTSSST 531

  Fly   426 PTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMD-----MYPKILDFDPVVMSSFTMTL 485
            .......:.:..|..:...:.|......|::..|||.|::     ::| .|..:.:...|.:..:
plant   532 SGQHGGYIKYVMLTGAKLFSEVVDEAHAVILAGGTLQPIEETRERLFP-WLPSNQLQFFSCSHIV 595

  Fly   486 ARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVA 550
            ....::|:.||.|....:......:|....:|:..|.|:..:...||:||:.||:|:.|...|..
plant   596 PPESIMPIAVSHGPSGQSFDFSHSSRSSIGMIQELGLLMSNLVAVVPEGIIVFFSSFEYETQVHT 660

  Fly   551 SWYDQGIVDTLLRYKLLFIETQDNAETSYALMNYVKACDCGRGAVLLAVARGKVSEGVDFDHHYG 615
            :|.:.||:..:::.|.:|.|.:.|.|....|.:|.:|.:..|||::|||..||||||::|.....
plant   661 AWSNSGILRRIVKKKRVFREPRKNTEVEAVLRDYKEAIESERGAIMLAVVGGKVSEGINFSDSMC 725

  Fly   616 RAVLMFGIPYVYTQSRILKARLDYLR---DQFQIRENDFLTFDA--------------------- 656
            |.|:|.|:||.......|..|:.::.   |...|:.:..|..|:
plant   726 RCVVMVGLPYPSPSDIELLERIKHIEGRADSDSIKPSVTLVDDSYYSGDVQAGFGVLKSCKRRGK 790

  Fly   657 -------MRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKR--------SRLPKWIQEHLVDS 704
                   |:...|.:|||:|.:.||..::..|.|:|....:        ::|||||::.|:.|
plant   791 EYYENLCMKAVNQSIGRAIRHEKDYASILLVDARYSNDPSKRTSHSHPSNKLPKWIKDRLIYS 853

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xpd	NP_726036.2	rad3	7..717	CDD:273169	186/908 (20%)
		DEXDc2	8..280	CDD:214693	70/398 (18%)
		HBB	270..413	CDD:284245	33/179 (18%)
		HELICc2	542..686	CDD:214694	48/174 (28%)
AT1G79890	NP_178107.1	DinG	1..846	CDD:224120	182/899 (20%)
		DEAD_2	187..375	CDD:284209	48/199 (24%)
		Helicase_C_2	636..849	CDD:290046	61/212 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186062at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820