DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Xpd and AT1G20750

DIOPT Version :9

Sequence 1:	NP_726036.2	Gene:	Xpd / 37414	FlyBaseID:	FBgn0261850	Length:	769	Species:	Drosophila melanogaster
Sequence 2:	NP_173498.3	Gene:	AT1G20750 / 838665	AraportID:	AT1G20750	Length:	1144	Species:	Arabidopsis thaliana

Alignment Length:	777	Identity:	183/777 - (23%)
Similarity:	289/777 - (37%)	Gaps:	229/777 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VDGLLVYFPYEYIYPEQYAYMLELKRSL-----DAKGHCLLEMPSGTGKTATLLSLIVAYM---- 60
            :.||.|.|||: .|..|.|:|..:..:|     |...|.|||.|:||||:.:||..::|:.
plant    29 IGGLQVEFPYQ-PYGTQLAFMSRVISTLDRAQRDGHSHALLESPTGTGKSLSLLCSVLAWQKSYK 92

  Fly    61 -----------------------VE-HPETVRKLIYCSRTVPEIEKVIAELQNLMVYYERHCPNP 101
                                   || |...:..:.|.|||..:|.:||.|.        |.....
plant    93 SRFPNGNLSHSKTQPSDIAGSSNVEPHEPQIPTIYYASRTHAQITQVIREY--------RKTGYR 149

  Fly   102 PPFTGLVLSSRKNMCIHPEVSKEREGKA-VDGKCYGLTASYIRERHEMDTETPICQYFEG----F 161
            .|.|  ||.|||..|.:..|    :||. ||.||..|.         .|.:...|..|.|    .
plant   150 VPMT--VLGSRKRYCTNSHV----QGKENVDEKCRLLL---------KDKKNIKCAEFNGVGRIL 199

  Fly   162 SLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMS 226
            :....:.|...||:.|:||                                  .||.:.|:..:.
plant   200 AYPSLQQTGHNGVHDIEDL----------------------------------VKIGKTVTGRLL 230

  Fly   227 RESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQG 291
            :.    |....|::::..::.|:.:....:.:..|.|..::::..:|        .:....:|:|
plant   231 KS----FTVHSNMEDIAREAGSINLEEDIIFKLKNELEQMSEVEPEI--------YDSLYEVVEG 283

  Fly   292 L-------KDASVQRDTDMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYIKTRLRVHHV 349
            |       ||:..:||.|...:|                ...|..|..|:.|           ::
plant   284 LISWIGRKKDSLAKRDVDHYFSN----------------WTGDRALKELKEF-----------NI 321

  Fly   350 VQES----PAGFLKDISSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLITHF----ATL 406
            .:|:    .|.|.:.|:.....|..|.:       ..|..:.:|.|.|..|  .:|:|    .:.
plant   322 TRENFPNLKACFNQAITKSEAAEIDPDK-------PYLSGISVSTLEELFA--TLTYFFSRNGSH 377

  Fly   407 VSTYTKGFTIIIEPFDDK-TPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMY--- 467
            |..|..|.....:..|:. |.|.|     ..|::.|:....:.....::::||||||||:.:
plant   378 VLDYEMGLQRSAKRGDNGWTNTFS-----LWCMNPSVVFKDLADLSLSIILTSGTLSPMNSFSSE 437

  Fly   468 -----------PKILDFDPVVMSSFTMTLARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYG 521
                       |.::|.:..|.:....|:           .||  ..:::.:.|.|..|.....|
plant   438 LGMQFGTCLEAPHVIDPNMQVWAGAISTV-----------PGN--YPLNASYRTAEAYAFQDALG 489

  Fly   522 QLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIE----TQDNAETSYALM 582
            :.|.|:...||.|.:.||.||..:|.:...|::.|....|.....||||    ::|:.||  .|.
plant   490 KSLEEICTIVPGGSLVFFPSYKLMEKLCTRWHETGQWSRLCLKTDLFIEPRGGSKDDFET--VLK 552

  Fly   583 NY----------------VKAC---------DCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFG 622
            .|                ||..         |..||:..|||.|||||||:||.....|||::.|
plant   553 EYYDSISGKNRLIGRNSSVKKAGSVITEAQDDSKRGSAFLAVCRGKVSEGMDFSDDNARAVIIVG 617

  Fly   623 IPYVYTQSRILKARLDYLRDQFQIREN-----DFLTFDAMRHAAQCVGRALRGKTDYGIMIF 679
            ||.......:::.:..| .|..:..:|     ::....|.|...|..||.:|.:.|||.:||
plant   618 IPLPNLGDILVELKRKY-NDTNKSSKNLLGGSEWYCQQAYRALNQAAGRCIRHRFDYGAIIF 678

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xpd	NP_726036.2	rad3	7..717	CDD:273169	183/775 (24%)
		DEXDc2	8..280	CDD:214693	70/309 (23%)
		HBB	270..413	CDD:284245	29/157 (18%)
		HELICc2	542..686	CDD:214694	51/172 (30%)
AT1G20750	NP_173498.3	rad3	31..679	CDD:273169	183/775 (24%)
		P-loop_NTPase	32..>227	CDD:304359	64/252 (25%)
		Helicase_C_2	492..679	CDD:290046	59/190 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186062at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820