DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Xpd and AT1G20720

DIOPT Version :9

Sequence 1:	NP_726036.2	Gene:	Xpd / 37414	FlyBaseID:	FBgn0261850	Length:	769	Species:	Drosophila melanogaster
Sequence 2:	NP_001322805.1	Gene:	AT1G20720 / 838662	AraportID:	AT1G20720	Length:	1269	Species:	Arabidopsis thaliana

Alignment Length:	903	Identity:	213/903 - (23%)
Similarity:	356/903 - (39%)	Gaps:	256/903 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VDGLLVYFPYEYIYPEQYAYMLELKRSLD---AKGHC--LLEMPSGTGKTATLLSLIVAYM---- 60
            :.||.|.|||: .|..|.|:|..:..:||   ..|||  |||.|:||||:.:||..::|:.
plant    29 IGGLQVEFPYQ-PYGTQLAFMSRVISTLDRAQRDGHCHALLESPTGTGKSLSLLCSVLAWQQNYK 92

  Fly    61 ------------------------------------------VEHPETVRK-------LIYCSRT 76
                                                      ||..||..|       :.|.|||
plant    93 SRLLKGNLSHSKAAPEAATDPLNHGGGFIPETQPSDTPASTNVEKAETATKKRTKIPTIYYASRT 157

  Fly    77 VPEIEKVIAELQNLMVYYERHCPNPPPFTG-----LVLSSRKNMCIHPEVSKEREGK-AVDGKCY 135
            ..:|.:||.|.:.               ||     .||:|||:.|.:..|.    || .||.:|.
plant   158 HSQITQVIREYRK---------------TGYRVPMAVLASRKHYCTNRHVL----GKDNVDDECR 203

  Fly   136 GLTASYIRERHEMDTETPICQYFEGFS-LEGKESTLPVG---VYSIDDLKEYGRSRNWCPYFLAR 196
            .|    ::::..:.     |..|:..: :....|..|.|   |:.|:||.:.|::...||||.:.
plant   204 LL----LKDKANIQ-----CSEFKNVNKITSHPSLQPRGHNEVHDIEDLVKVGKNVRGCPYFASW 259

  Fly   197 YAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTN 261
            ....:|.:|...|.|:::|.|...|..:: :.:.::||||||::::..::.|:.:...|:.:..|
plant   260 SMAENAQLVFCPYSYIVNPVIRAGVEVDL-KGAIIIFDEAHNMEDIAREAGSINLEEDTLFKLQN 323

  Fly   262 ALNHLTKLVQDIREEDTNRLNEEYQ---RMVQGL-------KDASVQRDTDMILANPVLPNDVLT 316
            .|..::.....|           ||   .:|:||       ||:..:||.....:: ...:..|.
plant   324 ELEQMSVAQPMI-----------YQPLCEVVEGLISWIGRKKDSLAKRDFQHYFSS-WTGDKALR 376

  Fly   317 EVVPGNIRNADHFLSFLRRFIEYIKTRLRVHHVVQESPAGFLKDISSKICIERKPLRFCAERLSS 381
            |:...|| ..:.|...|..|.:.|:|...                              ||..|.
plant   377 ELEESNI-TRECFPILLECFTKAIRTSKE------------------------------AEMESD 410

  Fly   382 LLRTLEISDLTEYGALTLITHFATLVSTYTKGFTIII-------EPFDDKTPTVS----NPILHF 435
            :|....||.||.....:.:|:|.:...::...:.:.:       :|....|.|.|    ||.:.|
plant   411 MLYLSGISVLTLEELFSSLTYFFSRNGSHILDYQLGLQRSTKRGDPSGTWTHTFSLWCMNPAVVF 475

  Fly   436 SCL-DSSIAMAPVFSRFQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTLARPCLL-PMI---- 494
            ..| |.|:          :|::||||||||:.:...|..      .|..:|..|.:: |.:
plant   476 KDLADISL----------SVILTSGTLSPMNSFSSELGM------QFGTSLEAPHVIDPNMQVWA 524

  Fly   495 --VSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGI 557
              :|.|.....:::.::|.:..:.....|:.|.|:...||.|.:.||.||..:|.:...|.:...
plant   525 GAISNGPSNYPLNASYKTADAYSFQDALGKSLEEICTIVPGGSLVFFPSYKLMEKLCMRWRETEQ 589

  Fly   558 VDTLLRYKLLFIETQDNAETSY--ALMNYVKAC-------------------------DCGRGAV 595
            ...|...|.||:|.:..|:..:  .|..|..:.                         |..:||.
plant   590 WSRLCLKKDLFVEPRGGAQDEFDSVLKGYYDSIRGKNKIIGRNRRAKKAGPIKTETQDDSKKGAA 654

  Fly   596 LLAVARGKVSEGVDFDHHYGRAVLMFGIPY----------------VYTQSRILKARLDYLRDQF 644
            .|||.|||||||:||.....|||::.|||:                .|..|:.|....::...|
plant   655 FLAVCRGKVSEGIDFADDNARAVIIVGIPFPNLHDIQVGLKKKYNDTYKSSKSLLGGSEWYCQQ- 718

  Fly   645 QIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQEHL--VDSFCN 707
                       |.|...|..||.:|.:.|||.:||.|:|:.....|:.:.||:::.:  .|:|
plant   719 -----------AYRALNQAAGRCIRHRFDYGAIIFLDERYKEQRNRASISKWLRQSIKVYDNF-- 770

  Fly   708 LSTEEAVQLARRWLRRMAQPF------TREDQLGISLLTLAQLENMEQEKLERQAQGK 759
               |.:::..|.:...:.:..      ::||.:..:.  .::.::.|..:.|.|.|.|
plant   771 ---EASMEGLRSFFNSVKEQVDSKMLGSQEDSVEKNF--SSEKQSKEFRRKENQIQNK 823

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Xpd	NP_726036.2	rad3	7..717	CDD:273169	205/851 (24%)
		DEXDc2	8..280	CDD:214693	85/339 (25%)
		HBB	270..413	CDD:284245	29/152 (19%)
		HELICc2	542..686	CDD:214694	49/186 (26%)
AT1G20720	NP_001322805.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186062at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820