Protein Alignment Xpd and ddx11

DIOPT Version :9

• Sequence 1: NP_726036.2
• Gene: Xpd / 37414
• FlyBaseID: FBgn0261850
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: NP_001164296.1
• Gene: ddx11 / 493192
• XenbaseID: XB-GENE-969935
• Length: 895
• Species: Xenopus tropicalis
• Alignment Length: 900
• Identity: 195/900 - (21%)
• Similarity: 329/900 - (36%)
• Gaps: 247/900 - (27%)

  Fly     5 VDGLLVYFPYEY-IYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLL--------------- 53
            ||...:.||:.| .||.|..:|.:|.::|:|....:.|.|:||||:.:|:
 Frog     6 VDPAALTFPFPYEPYPIQEQFMEKLYQALEAGKVGIFESPTGTGKSLSLICGALTWLQDFETKKR 70

  Fly    54 -----SLIVA------------------------------------------------------- 58
                 :|.||
 Frog    71 QEEAQALSVADTELKEKDTSASSTEPDWIAQFVQMKEEMDIKNKIKEEQLRRKKREEHLKQMKHN 135

  Fly    59 ----------------------------------------------YMVEH-------------- 63
                                                          .:||:
 Frog   136 VQLKFASKRKREEDDETMRLLQLSQQILSGGGEKEAIELDKEEQELLLVEYESDEETKKGPDRLE 200

  Fly    64 ------PETVRKLIYCSRTVPEIEKVIAELQNLMVYYERHCPNPPPF---TGLV-LSSRKNMCIH 118
                  .|.|.|:.|||||..::.:.:.|:|.            .||   |.|| |.||:|||::
 Frog   201 DEEDLEEEHVTKIYYCSRTHSQLSQFVHEVQK------------SPFGKQTRLVSLGSRQNMCVN 253

  Fly   119 PEVSKEREGKAVDGKCYGLTASYIRERHEMDTETP----------ICQYFEGFSLEGKESTLPVG 173
            .:|.:....:.::.:|..:.    |.:||...:.|          .|.::....::.......|.
 Frog   254 DDVRRLGNVQLINDRCMEMQ----RNKHEKKNKEPERKKRQESRAACPFYSYEQMQFLRDETLVE 314

  Fly   174 VYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMS----RESCVVFD 234
            |..|:.|....|....|||:.:||||..|.:||..|..||...     |::.|    ::..|:.|
 Frog   315 VKDIEQLVSLAREVKACPYYSSRYAIPTAQVVVLPYQMLLHES-----SRKASGIKLKDQVVIID 374

  Fly   235 EAHN-IDNV-CIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQGLKDASV 297
            |||| ||.: |:.|..|. ..:..:..:..:.::.:....::.:     |..|.:.:..|.:..|
 Frog   375 EAHNLIDTITCMYSSQVS-GAQLCQAHSQLMQYMDRYRSRLKAK-----NLMYVKQLVFLLEKFV 433

  Fly   298 QRDTDMILANPVLP------------NDVLTEVVPGNIRNADHF-------LSFLRR----FIEY 339
            |.....:..||...            ||.|..   ..|.|.:.|       .|.:.|    |:|.
 Frog   434 QVMGGNVKQNPSFQKVAQDGTTLKSINDFLFH---SQIDNINLFKIQRYCTKSMISRKLSGFVEK 495

  Fly   340 IKTRLRVHHVVQESPAG---FLKDISSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLIT 401
            .|.........:...||   ||:|:|.|       .|.........|...|...|.....|..|.
 Frog   496 FKGTETCLANKESQKAGLQQFLQDLSQK-------SRHTVGAPEGALEDAENGQLRTASPLMQIE 553

  Fly   402 HFATLVSTYTKGFTIIIEPFDDKTPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDM 466
            .|.:.::...:...:|:.    ...||:...|.|..|:.::..|.|....::|:|..||:.|:..
 Frog   554 GFLSALTNANQDGRVILH----MQGTVAQSSLKFLMLNPAVHFAEVLKECRSVIIAGGTMQPVSD 614

  Fly   467 YPKIL----DFDPVVMSSFTMTLARPC--LLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLV 525
            :.:.|    ...|..::.|:.....|.  :||:::..|.....:...::.|:...::...|::|.
 Frog   615 FKQQLLISAGLSPERITEFSCGHVIPAENILPIVLCSGPTNQQLEFTYQKRDLPEMMDETGRILT 679

  Fly   526 EVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAETSYALMNY---VKA 587
            .:...||.|:||||.||.|.:.:...|...|::..|...|.:|.|.:...:....|:.|   :|.
 Frog   680 NLCNFVPGGLVCFFPSYEYQKRIQEHWEKSGLLKRLALKKKIFQEPKRANQVDQVLVEYSKCIKN 744

  Fly   588 CD----CGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRE 648
            |.    ...||:|.:|..||:|||::|....||.::|.|:||...:|..|:.::.||.......|
 Frog   745 CSQSGGAQNGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIRSPELQEKMSYLDKTLPKTE 809

  Fly   649 -----NDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQ 698
                 ...:....|:...|.:|||:|.:.||..::..|.|:||.....:||:||:
 Frog   810 GVSAGRVLIENLCMKAVNQSIGRAIRHRGDYASIVLLDHRYSRPAILGKLPQWIR 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xpd	NP_726036.2	rad3	7..717	CDD:273169	193/897 (22%)
		DEXDc2	8..280	CDD:214693	81/433 (19%)
		HBB	270..413	CDD:284245	32/168 (19%)
		HELICc2	542..686	CDD:214694	43/155 (28%)
ddx11	NP_001164296.1	P-loop_NTPase	11..418	CDD:304359	81/433 (19%)
		DEXDc	15..>136	CDD:214692	18/120 (15%)
		rad3	210..876	CDD:273169	170/695 (24%)
		Helicase_C_2	678..866	CDD:290046	58/186 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D141017at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010