Protein Alignment Xpd and CG11403

DIOPT Version :10

• Sequence 1: NP_726036.2
• Gene: Xpd / 37414
• FlyBaseID: FBgn0261850
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: NP_569898.1
• Gene: CG11403 / 31072
• FlyBaseID: FBgn0026876
• Length: 861
• Species: Drosophila melanogaster
• Alignment Length: 893
• Identity: 196/893 - (21%)
• Similarity: 324/893 - (36%)
• Gaps: 273/893 - (30%)

  Fly    11 YFPYEYIYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMVEHPETVR------- 68
            |.|||.    |...|.||.:.|:.....:.|.|:||||:.||....:.::..|.|.||
  Fly    22 YSPYEI----QEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEMLARI 82

  Fly    69 ----------------------------------------------------------------- 68
                                                                             
  Fly    83 RGVEQELAKLKEESEQSSNWLESQGKSRAQRAELLRLQHLQALLDKQEQQLDQIRKGAKKHKRQG 147

  Fly    69 -----------------------------------------KLIYCSRTVPEIEKVIAELQNLMV 92
                                                     ::.:||||..::.:::|||
  Fly   148 RVHPGKLEELEKDLDPESDSDSEHETADGPQEAAEDRYRPVQIFFCSRTHSQLAQIVAEL----- 207

  Fly    93 YYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRER--------HEMD 149
               |..|:......:.|.||:.:|.:|.|.|.:....::.:|..:.....|..        .|.:
  Fly   208 ---RKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDMATKKARPNPSKKSRLTAEAN 269

  Fly   150 TETPICQYFEGFSL-EGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLL 213
            :..|    |:..|| |............|::|...|.:...|.|:.:|.|:.||.:::..|..||
  Fly   270 SRCP----FKAASLVESLRDLALTEPLDIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLL 330

  Fly   214 DPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMS----VKINRRTVER---------------- 258
            .......:...: :.|.|:.|||||:    :||::    .:|:|:.:||
  Fly   331 QKSARNQLGISL-KGSIVIVDEAHNL----LDSVAQLHGSEISRQQLERAKVQISGYKDHFQKRF 390

  Fly   259 -STNAL---------NHLTKLVQDIREEDTN--------RLNEE-------------------YQ 286
             :.|.|         ..|.|::...:|..:|        .|..|                   :.
  Fly   391 TTKNLLKINQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDFFNIDLCELLDFCARTRFA 455

  Fly   287 RMVQGLKD------------ASVQRDTDMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEY 339
            |.|||..|            |.|.....:||..                      |:..::..|.
  Fly   456 RKVQGRADRMEREPRPSENQAPVSTARSLILQR----------------------LASEQKLKEK 498

  Fly   340 IKT-RLRVHHVVQESPAGFLKDISSKICIERKPLRFCAERLS-SLLRTLEISDLTEYGALTLITH 402
            .|: :.||..:.:|..|..|::       ::||.:...|.:: |.:|             .|:..
  Fly   499 TKSVKRRVEDINKEDKAEELQE-------QQKPTKKPVEEVAPSPIR-------------PLLAF 543

  Fly   403 FATLVSTYTKGFTIIIEPFDDKTPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMY 467
            ..||.|....| .|:::|.        ...|.:..||.:...|.:.:..:.:||..||:.|....
  Fly   544 LETLTSNAEDG-RILVDPV--------GGTLKYILLDPAEQFADIVAEARAIVIAGGTMQPTKEL 599

  Fly   468 PKIL---DFDPVVMSSFTMTLARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAK 529
            .:.|   ..|.:|...:...:|...:||.::|.|.....:|.||..|....::|....:|..:.:
  Fly   600 KEQLFTGCHDRLVERFYNHVVANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQ 664

  Fly   530 TVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAETSYALMNYVKAC--DCGR 592
            .||.|:|||..||.||:.|.......|.::|:...|.:|.|...:||  ..|.||..|.  ....
  Fly   665 VVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGSAE--QLLDNYALAIKRPASY 727

  Fly   593 GAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQF-QIRENDFLTFDA 656
            ||:||:|..||:|||::|....|||||:.|:||..:.|..|:.|:.:|.::. ....|::.....
  Fly   728 GALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGPGAGNEYYENLC 792

  Fly   657 MRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQEHLVDS 704
            ::...||:|||:|...||..:...||||:....|.:|||||..|:|::
  Fly   793 VKAVNQCIGRAVRHIKDYACVYLLDKRFADPKIRGKLPKWISRHIVEA 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xpd	NP_726036.2	rad3	7..717	CDD:273169	196/893 (22%)
CG11403	NP_569898.1	DEAD-like_helicase_N	42..>101	CDD:475120	12/58 (21%)
		rad3	187..837	CDD:273169	173/719 (24%)