Protein Alignment Xpd and rtel-1

DIOPT Version :10

• Sequence 1: NP_726036.2
• Gene: Xpd / 37414
• FlyBaseID: FBgn0261850
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: NP_492769.1
• Gene: rtel-1 / 172946
• WormBaseID: WBGene00009124
• Length: 994
• Species: Caenorhabditis elegans
• Alignment Length: 873
• Identity: 213/873 - (24%)
• Similarity: 376/873 - (43%)
• Gaps: 192/873 - (21%)

  Fly     8 LLVYFPYEYIYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMVEHPET------ 66
            |.|.||:| .|..|..:|..:...||.|....||.|:|||||.:||...:|::....||
 Worm    17 LSVKFPFE-PYECQRIFMKNVVDVLDRKLDAALESPTGTGKTLSLLCSTLAWVQRQKETKPLDFA 80

  Fly    67 ---------------------VRKLIYCSRTVPEIEKVIAELQNLMVYYERHCPNPPPFTGLVLS 110
                                 |..:.|.|||..::|:|:.||......:.:         ..:|.
 Worm    81 TWQTSGAGGAEKTDEKLKSAYVPTIFYASRTHSQLEQVVHELNRTEYKWVK---------TTILG 136

  Fly   111 SRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMDTETPICQYFEGF---SLEGKESTLPV 172
            ||::.||:.:|.|.:|.......|.||.:.            ..|.|:..|   :.:.....|..
 Worm   137 SREHFCINQKVKKIKESNRQAHVCRGLVSK------------RACHYYNKFDACTTDKMTEFLDK 189

  Fly   173 G-VYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVFDEA 236
            | ...|:|..:.|...:.||||::|.....|.:::..|:|::|||:.:....:: :.|.|:||||
 Worm   190 GEAMDIEDFVKLGTQNSLCPYFMSRQRSETAELILLPYNYIIDPKMRRRYKLDL-KNSIVIFDEA 253

  Fly   237 HNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQ-------------RM 288
            ||::::|..:.|.::...::......|..:..|:.|  ||:|.|...:.:             ::
 Worm   254 HNLESICESNASAELTSTSIALCIEELKKVLALLVD--EEETARSEADAETGAFGSAKIDLTKKL 316

  Fly   289 VQGL----------KDASVQRDTDMILANPVLPNDVLTEVVP---GNIRNADHFLSFLRRFIEYI 340
            ::.|          |..|::.:.|.:..:..|.:      ||   |...:.:..|..|.:
 Worm   317 IENLRTEDLMTVLEKIFSLEEEMDKLFGSSQLKS------VPPLSGKASDGEILLETLAK----- 370

  Fly   341 KTRLRVHHVVQESPAGFLKDISSKICIER--KPLRFCAERLSSLLRTLEISDLTEYG-ALTLITH 402
                          |||  |.:|   :||  ..||   :.:|.||...|...|||.| .:..:..
 Worm   371 --------------AGF--DANS---VERLVDVLR---DAISYLLSKNEEVALTEKGDGMEKVAD 413

  Fly   403 F-ATLVSTYTKGFTI--------IIEPFDDKTPTVSNPI------------LHFSCLDSSIAMAP 446
            | .::.||:.:....        :::..|.||...:..:            :.:.|..:||:|..
 Worm   414 FLLSIYSTHAQDVAAAVGEETVKLVDRVDPKTVARNCKLYIQKDKDNEKLTIKYFCFQASISMRM 478

  Fly   447 VFSR-FQTVVITSGTLSPMD--MYPKILDFDPVVMSSFTMTLARPCLLPMIVSKGNDQVTISSKF 508
            :..| .:.|::.||||||:.  .|...|:|..::.:..  .|.:..:|..||::|. :..::..|
 Worm   479 LKMRGVRNVLLASGTLSPIQAFTYNMGLNFGAILENEH--ALKQVPVLTSIVTRGK-RGGLAGSF 540

  Fly   509 ETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASW--------YDQGIVDTLLRYK 565
            :.|::...:....:.|:.|.:.:|.||:.||:||..::.:||:|        .::...:.:.:.|
 Worm   541 QNRKNLDYVTGVAEALLRVMEVIPQGILIFFSSYSQMDELVATWKTTKWSSNSNESFWEKMEKTK 605

  Fly   566 LLFIETQDNAETSYALMNYVKACDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPY--VYT 628
            .:.:|.:...|.:...:.|.:......||.||||.|||||||:||.....|||::.||||  ::.
 Worm   606 RVVVEPRAKEELAAIRLRYTQGVSEQHGAALLAVCRGKVSEGIDFCDAESRAVIIIGIPYPPIHD 670

  Fly   629 QSRILKAR-LDYL---RDQFQIREN--DFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRH 687
            :..:||.. ||.|   :|....|::  |:...:|.|...|.:||.||.|.|:|.::..|.|:: .
 Worm   671 ERVVLKKMYLDDLMGRKDTKSERQSSQDWYQMEAFRAVNQAIGRVLRHKDDFGTVVLMDTRYA-S 734

  Fly   688 DKRSRLPKWIQE----------------------HLVDSFCNLSTEEAVQLAR-----RWLRRMA 725
            .|....|||::.                      ||::   |..||...:.|:     |.:::.|
 Worm   735 AKPEMFPKWLRNTISRSDTDGCALKTSRFFKERGHLIE---NSKTEYIKKQAKQCKSFRQVKQTA 796

  Fly   726 QPFTREDQLGISLLTLAQLENMEQEKLE 753
            ...:::|.:.|:|..:....||:.||.|
 Worm   797 ASDSKDDIIEITLEDMFSPANMKLEKKE 824

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xpd	NP_726036.2	rad3	7..717	CDD:273169	202/830 (24%)
rtel-1	NP_492769.1	rad3	16..761	CDD:273169	197/805 (24%)