Protein Alignment Xpd and rtel1

DIOPT Version :10

• Sequence 1: NP_726036.2
• Gene: Xpd / 37414
• FlyBaseID: FBgn0261850
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_031750114.1
• Gene: rtel1 / 100487920
• XenbaseID: XB-GENE-6035930
• Length: 1269
• Species: Xenopus tropicalis
• Alignment Length: 825
• Identity: 208/825 - (25%)
• Similarity: 358/825 - (43%)
• Gaps: 157/825 - (19%)

  Fly     2 KLSVDGLLVYFPYEYIYPEQYAYMLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMVEH--- 63
            ::.|.||.|.||:: .|..|..||.::.:.|....:.:||.|:|||||..||...:|:...:
 Frog     3 QVPVAGLTVDFPFQ-PYKCQEDYMGKVIQCLQQGVNGVLESPTGTGKTLCLLCATLAWRQHYKDG 66

  Fly    64 ----------------PE--------------------TVRKLIYCSRTVPEIEKVIAELQNLMV 92
                            ||                    .|.|:||.|||..::.:||:||:: .|
 Frog    67 ISARKIAERMNGAELFPERPAAAWGGASAEGQASAYYSDVPKIIYASRTHSQLTQVISELKH-TV 130

  Fly    93 YYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMDTETPICQY 157
            |..:.|         ||.||:.:||||||.|:....|....|          |.::.|.|  |.:
 Frog   131 YRPKVC---------VLGSREQLCIHPEVKKQESNHAKVHMC----------RSKVSTRT--CHF 174

  Fly   158 FEGFSLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVS 222
            :.....:..|..|...:..|:||.:.|.....|||:|:|.....|.|:...|:||||||..:..:
 Frog   175 YNNVEEKSTEKDLTNHILDIEDLVKSGTKHRACPYYLSRNLKQQADIIFMPYNYLLDPKSRRAHN 239

  Fly   223 KEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQR 287
            .:: :.:.|:||||||::.:|.||.|..:....:....:|::.:.|  :.:...:..|...|:..
 Frog   240 IDL-KGTVVIFDEAHNVERMCEDSSSFDLTPYDLASGIDAMDLVLK--EQMENVEQKRYQAEFNM 301

  Fly   288 MVQG------LKDASVQRDTDMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYIKTRLRV 346
            ..|.      |:|.:..:...|.|.|.:    ..|::.||.        ..:.:...||......
 Frog   302 DSQSSGLTLELEDLAKVKAALMQLENSI----ESTQLPPGG--------GGVTKVGSYIFQLFAA 354

  Fly   347 HHVVQESPAGFLKDI---------SSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLITH 402
            ..:..::.|..|:.:         ||.|......|    ::|:.:::.:...:..| ||  .::.
 Frog   355 SGITFDTKAKLLESLEQIIQHVGGSSGIFTNTMGL----QKLADIIQIVFSMEPPE-GA--NVSS 412

  Fly   403 FATLVSTYTKGFTIIIEPFDD--KTP---TVSN------PILHFSCLDSSIAMAPVFSR-FQTVV 455
            |...:|.|.|   :.|.|..:  |.|   ..||      .:|.:.|......|..:..: .:.|:
 Frog   413 FNQNISKYYK---VHIHPDTNQRKKPRGDVWSNSKKQGGKVLSYWCFSPGYTMHDLVRQGVRCVI 474

  Fly   456 ITSGTLSPMDMYPKILDFDPVVMSSFTMTLARPCLLPM--------------IVSKGNDQVTISS 506
            :|||||.|              :|||||.:..|..:.:              ||.:|.|...:||
 Frog   475 LTSGTLCP--------------LSSFTMEMQIPFPVSLENPHVIDKHQIWVGIVPRGPDGSQLSS 525

  Fly   507 KFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIET 571
            .::.|.....:.:.|:.:..:|:.||.|::.||.||..|:..:..|.::|:...:...|.:|:|.
 Frog   526 SYDRRFSEEYLSSLGKTIGNIARVVPHGLLVFFPSYPVLDKSIEFWKERGLSAKIDDVKPMFVEP 590

  Fly   572 QDNAETSYALMNY---VKACDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRIL 633
            :.....:..:..|   :::.: |.||..|||.|||.|||:||..:.||.|::.|:|:.......:
 Frog   591 RGKGSFTEVIDAYYEKIRSAN-GSGASFLAVCRGKASEGLDFADNNGRGVIITGLPFPPRMDPRV 654

  Fly   634 KARLDYL----RDQ----FQIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKR 690
            ..::.:|    |.|    ..:...::....|.|...|.:||.:|.:.|||.:...|.||::.|.|
 Frog   655 VLKMQFLDEMRRSQGSAGLYLSGQEWYRQQASRAVNQAIGRVIRHRNDYGAIFLCDHRFNQSDAR 719

  Fly   691 SRLPKWIQEHL--VDSFCNLSTEEAVQLARRWLRRMAQPFTREDQ 733
            ::||.|::.::  .|:|.:: ..:..|..|..|:.|..|....||
 Frog   720 AQLPSWVRPYVRTYDNFGHI-IRDVSQFFRVALKIMPTPTLHSDQ 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xpd	NP_726036.2	rad3	7..717	CDD:273169	201/802 (25%)
rtel1	XP_031750114.1	rad3	8..741	CDD:273169	200/796 (25%)
		HN_RTEL1	881..981	CDD:259826
		HN_RTEL1	1028..1128	CDD:259826
		RING_Ubox	1207..1256	CDD:473075