DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4266 and Rbm15b

DIOPT Version :9

Sequence 1:	NP_001097394.1	Gene:	CG4266 / 37411	FlyBaseID:	FBgn0034598	Length:	1306	Species:	Drosophila melanogaster
Sequence 2:	NP_780611.3	Gene:	Rbm15b / 109095	MGIID:	1923598	Length:	887	Species:	Mus musculus

Alignment Length:	402	Identity:	80/402 - (19%)
Similarity:	113/402 - (28%)	Gaps:	172/402 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   955 NQRMGGPAGNGGNGVGPMFMRN----QGGGPGGAGPSGGG------------PGGAGTGGGGPGG 1003
            ::|...|:|.|.:.........    :.||...|..:.||            |.|:|.|||...|
Mouse     5 SERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGTKHPVPARARDKPRGSGGGGGHRDG 69

  Fly  1004 RQQGPGFFNPRNPFNDNQRGRGGQSGGGVRGVGGGGGGGPGGRGRWSDDEDEGGNNFKRRGGPGG 1068
            |..|          :.|.|..||:|           .|.|||          ||...|..|.||.
Mouse    70 RAAG----------DANHRASGGRS-----------SGAPGG----------GGRTGKASGDPGA 103

  Fly  1069 PGGNRFRGERGGEMMDDRRGNNSRGGRGGPREDRERPGFGNRRGSRDDSNRHSISSTDEGNKAAS 1133
            .|.:                         ||                                ||
Mouse   104 GGAS-------------------------PR--------------------------------AS 111

  Fly  1134 ETEPKPKNVETE-LGSTNTGAPAAATRVDTEEDWDQELQDYEARM--EAQKPGERASQSANSP-- 1193
            ...|.|.....| .|..:|.||...|.:.:........:..|.|:  :.::.||.:.:.:::|
Mouse   112 PLPPPPPPPGAEPAGPGSTAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPEL 176

  Fly  1194 ----------PQEKLPAENENFAK------------PADVTGDPLVAKSQTETSAACTPLYDELP 1236
                      ||:...|.....|:            |..:.|.....:|.:.::||.|      |
Mouse   177 GRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGSSRRSSSSSAAAST------P 235

  Fly  1237 PPAVPQTPTQPPKEPQGSPP---------RPAPPVIETEAAPHEESVPAPPAELQTEAPSAEEPI 1292
            ||..|     .|.:|.|..|         |...||                     .||...||.
Mouse   236 PPGPP-----APADPLGYLPLHGGYQYKQRSLSPV---------------------AAPPLREPR 274

  Fly  1293 APAASADVVAEA 1304
            |..|:|....:|
Mouse   275 ARHAAAAFALDA 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4266	NP_001097394.1	CID	7..125	CDD:239621
		RRM	<488..>593	CDD:223796
		RRM_SCAF4_SCAF8	490..566	CDD:240673
		DUF2413	1147..>1254	CDD:287302	26/132 (20%)
		Herpes_DNAp_acc	<1206..1304	CDD:282746	25/118 (21%)
Rbm15b	NP_780611.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..132		43/214 (20%)
		RRM1_RBM15B	134..215	CDD:240998	11/80 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	215..249		12/44 (27%)
		RRM2_RBM15B	325..409	CDD:241000
		RRM3_RBM15B	412..487	CDD:241002
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	549..703
		SR-25	568..>712	CDD:287471
		Nuclear localization signal. /evidence=ECO:0000255	590..594
		Interaction with Epstein-Barr virus BMLF1. /evidence=ECO:0000250	719..887
		SPOC	719..854	CDD:285043
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23189
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100