DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30389 and bif

DIOPT Version :9

Sequence 1:	NP_001261116.1	Gene:	CG30389 / 37410	FlyBaseID:	FBgn0050389	Length:	1037	Species:	Drosophila melanogaster
Sequence 2:	NP_001259457.1	Gene:	bif / 32119	FlyBaseID:	FBgn0014133	Length:	1305	Species:	Drosophila melanogaster

Alignment Length:	1063	Identity:	201/1063 - (18%)
Similarity:	329/1063 - (30%)	Gaps:	376/1063 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 RQRKQREVAKDNEFYMQLLQQALPAEEAAE-EAAAGQAATSSTVVVANGSATTPALVASSGATAA 244
            :||.||..:.:.     ||.:.....|..| |....|....||.....|:..||
  Fly   372 KQRLQRSTSLNT-----LLDRDDDEVEVEEPEMTNSQVRAKSTPPPILGAKPTP----------- 420

  Fly   245 NGVLATATQAQNHHEHHHSGGA-GASSSSSSNSNHHHHHHHNNSSGNSGSNHNSNSSSGG----- 303
                    :..:.|:...|.|| ||.|:.:..||.........::|.:||...|.....|
  Fly   421 --------KPSSQHQRPVSLGANGAGSAVNPPSNSDQAQTGAVANGGAGSGQRSRHFKRGNEVMK 477

  Fly   304 -AKD-----------NSTSESASGAAASSITASSATGAALAAAASASS----------------- 339
             |:.           ||...|.:||||::..:..|..|..||.:..:|
  Fly   478 RARSVEALLCEKSPWNSQRISTAGAAAAAAPSPPAPKATAAAPSPVTSPTCVTIEDKIHNARERL 542

  Fly   340 -----------------------------------ASTTSGSSSSSASTG--------------- 354
                                               ||......::..|.|
  Fly   543 HSGTDTAPPKRLTSIIDDTERPPPDLVKQTLKMFEASANRRPRAAHRSNGVGGVASKVANYKSII 607

  Fly   355 ---KQSSSSAASAATTGAATTSSTPV-------------SDFSALAASLATQQQQHQSV------ 397
               ||.||:||:...||....||||:             |..|||:..:...:.|....
  Fly   608 KDQKQPSSAAATPPPTGMGFASSTPLRHVHPDIIPRQVDSPVSALSVMMRRMELQEPETPERETR 672

  Fly   398 -ATAYPATSSARSSSSTSEGVDADGCCGATSNGHAGGSRNHRRSMDKDKHRNKGDAADNEHNNGT 461
             |.|.| .|.|.|.:..::..:.||                  .:|.|.|.|.    |::|::|.
  Fly   673 DAEATP-QSEALSETERNDRDEGDG------------------EVDDDNHNNN----DDDHDDGD 714

  Fly   462 RHGGKNSGNNQVDSAA-----------------------TATATVTATSSNSKDKDKEK-SDWDS 502
            .....|...:::.:||                       |..|.|.:.||:|......| |:.:.
  Fly   715 DGSDNNEQRDKMGAAAAGDKPKPPAESAAGGAQRSFAASTENAHVASGSSSSTSASVRKLSNNND 779

  Fly   503 STSYPQQQQQGGKEK---HEKKAGNA------VPNGNANHLEDETA-----SVEPTPPVEKATKG 553
            |:|.|...:|.|..:   :.:.||:.      :.....|.::..||     ||..:..|..|..|
  Fly   780 SSSGPAVTKQIGVIRPLFNSQGAGSTPLTSREIEKNRINEMKKSTATDAGGSVSGSGTVAGAGSG 844

  Fly   554 RRNR-------GKKDNAAKDNHSHQQQLAQQQKEKDKENTANNNNNDASSVSSSASSTSSNAIAN 611
            ....       ..|:.|:.:..:....|...:|.:::..||..    .|..|||..||.:.::..
  Fly   845 TSPTTSLDSVINTKEAASSETDASASPLWTLRKLRNQSQTAGG----GSGPSSSLHSTENTSMVF 905

  Fly   612 LASKVVSKICETCLKLEADVKKYRAEISHMKQIENELRQKLDANLTSKSTLQAKQKE-------- 668
            ..||...::.:   .:|:||..||.:....|  .||....|..:|:.:::......:
  Fly   906 NFSKSTKEVPD---YIESDVVIYRRKRELPK--PNEPGFVLLGDLSVETSTDTDYDDYSMCPPSP 965

  Fly   669 CDDLEKRIQELNNARHADMLNLQTVERRLNEERRQKQS---------LDSQLSNEKKARKLAEEK 724
            ||      .|..||      |: .::.:.:..::.|:|         |.|......:|....|:.
  Fly   966 CD------VEFENA------NI-VIDGKSSIRQKPKESSFRVQFNDTLTSTFEYPSEASMTIEDP 1017

  Fly   725 A-ARPECSSQCKQRRQQMDEEQKRLRSDLKQAEEAKQLAVEHGRKVEQEYRMLEAKLRNRESSQP 788
            . |.|  .....:..|.:..||..|....:|.|            :||.:::
  Fly  1018 PYADP--FGHVSKHHQMLLAEQMHLLQHQEQLE------------LEQMHQL------------- 1055

  Fly   789 DPEILLNALAAMQDKNATLEKNLSAET--------------------------RVKLDLFSALGA 827
                   .||..|..:.|:::.:...|                          .:.|| :.:||.
  Fly  1056 -------GLAPEQHHHVTVDEIIELPTSTAGHGHGIGLGHRSGAAGGGGTMLGNLPLD-YPSLGR 1112

  Fly   828 A---KRQIEISDNHRRSKEDEVIDLKAKIAQLLAVMPDNLCMNTGPHGPSSSILRMNDTPPLQSG 889
            .   .:..:.....::.:.:..|...|.:|.|...|...:.:.                |||
  Fly  1113 GIILPQSPQQQSTQQQEQPEPAIATSATVAGLAVAMATEVEIE----------------PPL--- 1158

  Fly   890 PGP-----SSPMLSLSAAQEYQQH------------QQHQQHQQHQQHQQHQQ------------ 925
            |.|     ..|.|....||:.||.            .|:....||.......|
  Fly  1159 PAPPVTVAKRPQLPAKPAQQQQQQAARRARPSVLLKPQYACFLQHDDDAPKSQPTAAGRPRKAAS 1223

  Fly   926 ---HQQHQQQQHQQHQQHQQQQHQQQHQQHQQHQQHQ--------QHQQQGGGGPGSQQQMVPVS 979
               ..|.|.::.|||..|.|.||||...:.....:.:        :|||:      .::..:|.|
  Fly  1224 FSLGNQRQSKEQQQHHHHYQPQHQQSKYERNDCSRSRGSCESPAPEHQQR------RRRPSLPSS 1282

  Fly   980 VAAAFQVAAANAAAAANAAAANG 1002
                  :|.:||::|...|...|
  Fly  1283 ------LALSNASSALLQARIPG 1299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30389	NP_001261116.1	Macoilin	2..893	CDD:286769	169/917 (18%)
		Ax_dynein_light	<624..711	CDD:287215	20/103 (19%)
		RILP-like	<696..803	CDD:304877	19/116 (16%)
bif	NP_001259457.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458110
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13289
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030