| Sequence 1: | NP_002225.2 | Gene: | KCNA5 / 3741 | HGNCID: | 6224 | Length: | 613 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001097131.2 | Gene: | Shawl / 5740840 | FlyBaseID: | FBgn0085395 | Length: | 937 | Species: | Drosophila melanogaster |
| Alignment Length: | 566 | Identity: | 185/566 - (32%) |
|---|---|---|---|
| Similarity: | 256/566 - (45%) | Gaps: | 152/566 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Human 121 RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRL 185
Human 186 RRPVNVSLDVFADEIRFYQLGDEAMER--------FREDEGFIK-------EEEKPLPR------ 229
Human 230 -----------NEFQR---QVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERE 280
Human 281 LLRH---------PPAPHQPPAPAPGAN--GSGVMAPPS---GPT-------------------V 312
Human 313 APL----------LPR----------------------------TLADP---FFIVETTCVIWFT 336
Human 337 FELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRV 401
Human 402 IRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAE--ADNQGTHF 464
Human 465 SSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFY-HRETD 528
Human 529 HEEP----AVLKEEQ-------------------GTQSQGPGLDRG 551 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNA5 | NP_002225.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..108 | ||
| 2 X 11 AA tandem repeat of D-[SP]-G-V-R-P-L-P-P-L-P | 61..82 | ||||
| BTB_2 | 122..213 | CDD:308049 | 35/98 (36%) | ||
| Ion_trans | 249..526 | CDD:306908 | 125/353 (35%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 282..304 | 6/32 (19%) | |||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 418..431 | 6/12 (50%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 480..485 | 4/4 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 532..559 | 11/43 (26%) | |||
| PDZ-binding. /evidence=ECO:0000250 | 611..613 | ||||
| Shawl | NP_001097131.2 | BTB | 7..99 | CDD:197585 | 35/92 (38%) |
| BTB_2 | 7..97 | CDD:280393 | 35/90 (39%) | ||
| Ion_trans | 307..506 | CDD:278921 | 96/214 (45%) | ||
| Ion_trans_2 | <449..499 | CDD:285168 | 37/49 (76%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||