Protein Alignment Hmg-2 and Hmgb2

DIOPT Version :9

• Sequence 1: NP_611553.1
• Gene: Hmg-2 / 37407
• FlyBaseID: FBgn0026582
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001350372.1
• Gene: Hmgb2 / 97165
• MGIID: 96157
• Length: 210
• Species: Mus musculus
• Alignment Length: 200
• Identity: 44/200 - (22%)
• Similarity: 82/200 - (41%)
• Gaps: 42/200 - (21%)

  Fly    13 PESPVSLPIASQ----------SMDTATIEDFDEDKPAKGKKKAKN---PKGRHSDSDIGSELKK 64
            |:|.|:....|:          :.:.:..||..:...|:..::.||   |||.          ||
Mouse    32 PDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDREMKNYVPPKGD----------KK 86

  Fly    65 LAQRRINVAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPYIEAA 129
            ..::..|   |||.|.:.:..|.::.|.:::.|.|..:..:..:.:||.|.:...:.|.||.:.|
Mouse    87 GKKKDPN---APKRPPSAFFLFCSENRPKIKIEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKA 148

  Fly   130 AKDKAIYQEQLQMFLKEHPEIVANELAKAKKATKLDGSPKEKTPKGESALGKAKKTKAKPVKRQS 194
            ||.|..|::.:..:..:     ....|..|...:..||.|:..|:.|           :..:.:.
Mouse   149 AKLKEKYEKDIAAYRAK-----GKSEAGKKGPGRPTGSKKKNEPEDE-----------EEEEEEE 197

  Fly   195 EDPDD 199
            |:.||
Mouse   198 EEEDD 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmg-2	NP_611553.1	HMGB-UBF_HMG-box	76..141	CDD:238686	18/64 (28%)
Hmgb2	NP_001350372.1	HMG-box	7..78	CDD:320749	8/45 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	71..102		12/43 (28%)
		HMG_box	95..162	CDD:278906	18/66 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..210		9/56 (16%)
		Required for chemotactic activity. /evidence=ECO:0000250|UniProtKB:P26583	165..180		2/19 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3288
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840