DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hmg-2 and 3xHMG-box2

DIOPT Version :9

Sequence 1:	NP_611553.1	Gene:	Hmg-2 / 37407	FlyBaseID:	FBgn0026582	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_194111.1	Gene:	3xHMG-box2 / 828480	AraportID:	AT4G23800	Length:	456	Species:	Arabidopsis thaliana

Alignment Length:	175	Identity:	46/175 - (26%)
Similarity:	84/175 - (48%)	Gaps:	39/175 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IEDFDEDKPAKGKKKAKNPKGRHSDSDIGSELKKLAQRRINVAGAPKMPLNGYVRFMNDRREELR 95
            :::.::|...|.||: |:|            ||            ||.|::.::.:.|:||..||
plant   235 VQEAEQDNKKKNKKE-KDP------------LK------------PKHPVSAFLVYANERRAALR 274

  Fly    96 REQPQRTALEHTRIIGEEWHQLPEERKLPYIEAAAKDKAIYQEQLQMFLKEHPEIVANELAKAKK 160
            .|  .::.:|..:|.||||..|.:::|.||.:.|.|:|..|.:.::.:.:...|...::..:.::
plant   275 EE--NKSVVEVAKITGEEWKNLSDKKKAPYEKVAKKNKETYLQAMEEYKRTKEEEALSQKKEEEE 337

  Fly   161 ATKLDG-------SPKEKTPKGESALGKAKKTKAKPVKRQSEDPD 198
            ..||..       ..||||   ::.:.|.|.||.|  |.::.||:
plant   338 LLKLHKQEALQMLKKKEKT---DNLIKKEKATKKK--KNENVDPN 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hmg-2	NP_611553.1	HMGB-UBF_HMG-box	76..141	CDD:238686	23/64 (36%)
3xHMG-box2	NP_194111.1	PTZ00121	<2..454	CDD:173412	46/175 (26%)
		HMGB-UBF_HMG-box	139..203	CDD:238686
		HMG-box	255..320	CDD:381793	23/66 (35%)
		HMGB-UBF_HMG-box	379..444	CDD:238686
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	57	1.000	Domainoid score	I4005
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810