Protein Alignment Hmg-2 and Hmgb4

DIOPT Version :10

• Sequence 1: NP_611553.1
• Gene: Hmg-2 / 37407
• FlyBaseID: FBgn0026582
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_081312.2
• Gene: Hmgb4 / 69317
• MGIID: 1916567
• Length: 181
• Species: Mus musculus
• Alignment Length: 206
• Identity: 46/206 - (22%)
• Similarity: 77/206 - (37%)
• Gaps: 41/206 - (19%)

  Fly    76 PKMPLNGYVRFMNDRREELRREQPQRTAL---EHTRIIGEEWHQLPEERKLPYIEAAAKDKAIYQ 137
            ||:.::.|:.||.:.|.:.:.:|| .|.|   |.:|...|:|..:.:..|..|...|..|||.||
Mouse     9 PKVNVSSYIHFMLNFRNKFKEQQP-NTYLGFKEFSRKCSEKWRSISKHEKAKYEALAELDKARYQ 72

  Fly   138 EQLQMFLKEHPEIVANELAKAKKATKLDGSPKEKTPKGESALGKAKKTKAKPVKRQSEDPDDVPL 202
            :::.           |.:.|.:|..|.|.....|.|.......:......|     .|:| |..:
Mouse    73 QEMM-----------NYIGKRRKRRKRDPKAPRKPPSSFLLFSRDHYAMLK-----QENP-DWTV 120

  Fly   203 AKVKRAQTPPPPTPPAAPVQPPPSSVPPATPAPRPLQPGEIPIYTNEFIEHNRSTENELR----- 262
            .:|.:|......|...|..:|               ...:..:...::.|...:..|:.:
Mouse   121 VQVAKAAGKMWSTTDEAEKKP---------------YEQKAALMRAKYFEEQEAYRNQCQGRKGN 170

  Fly   263 TLRKAKTDLEQ 273
            .|..|||.|:|
Mouse   171 FLESAKTSLKQ 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmg-2	NP_611553.1	HMG-box_HMG20	75..154	CDD:438796	22/80 (28%)
Hmgb4	NP_081312.2	HMG-box_HMGB_rpt1	8..76	CDD:438794	22/67 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..100		6/19 (32%)
		HMG-box_HMGB_rpt2	91..161	CDD:438795	12/90 (13%)