DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hmg-2 and Tox2

DIOPT Version :9

Sequence 1:NP_611553.1 Gene:Hmg-2 / 37407 FlyBaseID:FBgn0026582 Length:376 Species:Drosophila melanogaster
Sequence 2:XP_017447281.1 Gene:Tox2 / 311615 RGDID:735184 Length:561 Species:Rattus norvegicus


Alignment Length:264 Identity:66/264 - (25%)
Similarity:103/264 - (39%) Gaps:56/264 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 SPVSLPIASQSMDTATIED--------FDEDKPAKGK-KKAKNPKGRHSDSDIGSELKKLAQRRI 70
            ||.....|:.|..::|.|:        ..|.:|:... |||||||                :::.
  Rat   238 SPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSTDPGKKAKNPK----------------KKKK 286

  Fly    71 NVAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPY---IEAAAKD 132
            .....|:.|::.|..|..|.:..::.:.|..|..:.::|:...|..|.||:|..|   .|||.|:
  Rat   287 KDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKE 351

  Fly   133 --KAIYQEQLQMFLKEHPEIVANELAKAKKATKLDGSPKEK-----------TPK---------G 175
              ||:...:..:..|..|:....:.|:|....|: ..||:.           ||.         .
  Rat   352 YLKALAAYRASLVSKSPPDQGEAKNAQANPPAKM-LPPKQPMYAMPGLASFLTPSDLQAFRSAAS 415

  Fly   176 ESALGKAKKTKA-KPVKRQSEDPDDVPLAKVKRAQTPPPPTPPAAPVQPP----PSSVPPATPAP 235
            .::|.:...:|| .|....|..|...||:.....|.|.||......:.||    |:..||..|||
  Rat   416 PASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPAP 480

  Fly   236 RPLQ 239
            ..||
  Rat   481 MALQ 484

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hmg-2NP_611553.1 HMGB-UBF_HMG-box 76..141 CDD:238686 20/69 (29%)
Tox2XP_017447281.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5648
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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