Protein Alignment Hmg-2 and Tox2

DIOPT Version :9

• Sequence 1: NP_611553.1
• Gene: Hmg-2 / 37407
• FlyBaseID: FBgn0026582
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001359507.1
• Gene: Tox2 / 269389
• MGIID: 3611233
• Length: 541
• Species: Mus musculus
• Alignment Length: 279
• Identity: 68/279 - (24%)
• Similarity: 102/279 - (36%)
• Gaps: 65/279 - (23%)

  Fly    15 SPVSLPIASQSMDTATIED--------FDEDKPAKGK-KKAKNPKGRHSDSDIGSELKKLAQRRI 70
            ||.....|:.|..::|.|:        ..|.:|:... |||||||                :::.
Mouse   218 SPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSVDPGKKAKNPK----------------KKKK 266

  Fly    71 NVAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPY---IEAAAKD 132
            .....|:.|::.|..|..|.:..::.:.|..|..:.::|:...|..|.||:|..|   .|||.|:
Mouse   267 KDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKE 331

  Fly   133 --KAIYQEQLQMFLKEHPE------IVANELAKAKK-----------ATKLDGSPKEKTPKGESA 178
              ||:...:..:..|..|:      ..||..||...           |:.|..|..:....|.|.
Mouse   332 YLKALAAYRASLVSKSPPDQGEAKNTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSGASP 396

  Fly   179 LGKAKKTKAK---PVKRQSEDPDDVPLAKVKRAQTPPPPTPPAAPVQPP----PSSVPPATPA-- 234
            ...|:...:|   |....|..|...||:.....|.|.||......:.||    |:..||..||
Mouse   397 ASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPASM 461

  Fly   235 ---------PRPLQPGEIP 244
                     |.|..|.:.|
Mouse   462 ALQVQLAMSPSPPGPQDFP 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmg-2	NP_611553.1	HMGB-UBF_HMG-box	76..141	CDD:238686	20/69 (29%)
Tox2	NP_001359507.1	HMG-box	272..337	CDD:238037	20/64 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900