Protein Alignment Hmg-2 and Tox4

DIOPT Version :9

• Sequence 1: NP_611553.1
• Gene: Hmg-2 / 37407
• FlyBaseID: FBgn0026582
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_075923.2
• Gene: Tox4 / 268741
• MGIID: 1915389
• Length: 619
• Species: Mus musculus
• Alignment Length: 351
• Identity: 75/351 - (21%)
• Similarity: 126/351 - (35%)
• Gaps: 100/351 - (28%)

  Fly     9 PDAVPESPVS-LPIASQSMDTATIEDFDEDKPAK-------GKKKAKNPKGRHSDSDIGSELKKL 65
            |...||..:| .|..:.|:....::||....||:       |||: |.||
Mouse   165 PAQSPEDRLSTTPSPTNSLHEDGVDDFRRQLPAQKTVVVETGKKQ-KAPK--------------- 213

  Fly    66 AQRRINVAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPYIEAAA 130
             :|:......|:.|::.|..|..|.:..::.:.|..|..|.::|:...|..|.||:|..|
Mouse   214 -KRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVY----- 272

  Fly   131 KDKAIYQEQLQMFLKEHPEIVANELAKAKKATKLDGSPKEKTPKGESALGKAKKTKAKPVKRQSE 195
                          |...|....|..||..|.| |....:.|
Mouse   273 --------------KRKTEAAKKEYLKALAAYK-DNQECQAT----------------------- 299

  Fly   196 DPDDVPLAKVKRAQTPPPPTPPAAPVQPPPSSVPPATPAPRPLQPGEIP--IYTNEFIEH---NR 255
             .:.|.|..|.::|||.|         ||.::..||:|||...:...:|  |..|..:..   |:
Mouse   300 -VETVELDPVPQSQTPSP---------PPVTAADPASPAPASTESPALPPCIIVNSTLSSYVANQ 354

  Fly   256 STENELRTLRKAKTDLEQQNAVLEQHVDNTKAGYAKV------------MGEV-TELMEENQRLE 307
            ::..........|..:.:|  :|...:..::.|...|            :|:. |..::.:|:.:
Mouse   355 ASSGPGGQPNITKLIITKQ--MLPSSITMSQGGMVTVIPATVVTSRGLQVGQTSTATIQPSQQAQ 417

  Fly   308 TYLRALRQKLVAALGGISMPP--LEP 331
            ...|::.|...||...:.:||  |:|
Mouse   418 IVTRSVLQAAAAAAASMQLPPPRLQP 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmg-2	NP_611553.1	HMGB-UBF_HMG-box	76..141	CDD:238686	15/64 (23%)
Tox4	NP_075923.2	NHP6B	140..>306	CDD:227935	42/201 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..227		18/78 (23%)
		Nuclear localization signal. /evidence=ECO:0000255	213..218		2/20 (10%)
		HMG-box	223..288	CDD:238037	20/83 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..335		12/37 (32%)
		PHA03160	<464..530	CDD:165431

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810