DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hmg-2 and Ubtf

DIOPT Version :9

Sequence 1:	NP_611553.1	Gene:	Hmg-2 / 37407	FlyBaseID:	FBgn0026582	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001121162.1	Gene:	Ubtf / 25574	RGDID:	3927	Length:	764	Species:	Rattus norvegicus

Alignment Length:	332	Identity:	69/332 - (20%)
Similarity:	127/332 - (38%)	Gaps:	100/332 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 TATIEDFDE--DKPAKGKKKAKNPKGRHSDSDIGSELKKLAQRRINVAGAPKMPLNGYVRFMNDR 90
            |..|.|..|  ..|.||||..|:|                        ..||.||..|.||..::
  Rat    86 TELILDAQEHVKNPYKGKKLKKHP------------------------DFPKKPLTPYFRFFMEK 126

  Fly    91 REELRREQPQRTALEHTRIIGEEWHQLPEERKLPYIEAAAKDKAIYQEQLQMFLKEHPEIVANEL 155
            |.:..:..|:.:.|:.|:|:.:::.:|||::|:.||:...::|..::..|..|.::||:::.|
  Rat   127 RAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQN-- 189

  Fly   156 AKAKKATKLDGSPKEKTPKG----------------------ESALGKA------KKT-----KA 187
                 |.|.|...|.|||:.                      :.:|||.      ||.     ||
  Rat   190 -----AKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKA 249

  Fly   188 KPVKRQSED---------------PDDVPLAKVKRAQTPPPPTPPAAPVQPPPSSVPPATPAPRP 237
            ...:::.|:               .:.:..:.:.:|:..........|.:|||:|
  Rat   250 LEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNS---------- 304

  Fly   238 LQPGEIPIYTNEFIEHNR---STENELRTLRKAKTDLEQQNAVLEQHVDNTKAGY-AKVMGEVTE 298
                 ..:|..|.:.:.:   |||..:...::.|...:::.....:..|..|..| .:::..:..
  Rat   305 -----YSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLES 364

  Fly   299 LMEENQR 305
            |.||.|:
  Rat   365 LPEEEQQ 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hmg-2	NP_611553.1	HMGB-UBF_HMG-box	76..141	CDD:238686	19/64 (30%)
Ubtf	NP_001121162.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		HMG_box	112..179	CDD:395407	20/66 (30%)
		HMGB-UBF_HMG-box	196..261	CDD:238686	12/64 (19%)
		HMGB-UBF_HMG-box	299..358	CDD:238686	13/73 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	370..411		1/2 (50%)
		HMGB-UBF_HMG-box	407..470	CDD:238686
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	456..488
		HMG_box_5	479..562	CDD:373364
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	546..576
		HMGB-UBF_HMG-box	569..631	CDD:238686
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	648..764
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900