Protein Alignment Hmg-2 and Tox

DIOPT Version :9

• Sequence 1: NP_611553.1
• Gene: Hmg-2 / 37407
• FlyBaseID: FBgn0026582
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001364007.1
• Gene: Tox / 252838
• MGIID: 2181659
• Length: 526
• Species: Mus musculus
• Alignment Length: 380
• Identity: 77/380 - (20%)
• Similarity: 129/380 - (33%)
• Gaps: 144/380 - (37%)

  Fly    15 SPVSLPIASQSMDTATIEDFDED--KPAKGKKKAKNPKGRHSDSDIGSELKKLAQRRINVAGAPK 77
            ||.....|:.|..::..||..||  |...|:|:..        ||:|.:.|...:::......|:
Mouse   206 SPPGSKSATPSPSSSVHEDECEDASKINGGEKRPA--------SDMGKKPKTPKKKKKKDPNEPQ 262

  Fly    78 MPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPY---IEAAAKDKAIYQEQ 139
            .|::.|..|..|.:..::.:.|..|..|.::|:...|..|.||:|..|   .|||.|:   |.:|
Mouse   263 KPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKE---YLKQ 324

  Fly   140 LQMFLKEHPEIVANELAKAKKATKLDGSPKEKTPKGESALGKAKKTKAKPVKRQSEDPDDVPLAK 204
            |..:                                          :|..|.:...||.|
Mouse   325 LAAY------------------------------------------RASLVSKSYTDPVD----- 342

  Fly   205 VKRAQTP-----------------------------PPPTP------PAAP--VQPPPSSVPPAT 232
            ||.:|.|                             |..||      |:.|  :.|.|::..|.|
Mouse   343 VKTSQPPQLVNSKPSVFHGPSQAHSALYLSSHYHQQPGMTPQLTAMHPSLPRNIAPKPNNQMPVT 407

  Fly   233 ----------PAPRPLQPGEIPIYTNEFIEHNRS--------TENELRTLRKAKTDLEQQNAVLE 279
                      |.|..:.|   |::.:..::.::|        ::..::......:...||...|:
Mouse   408 VSIANMAVSPPPPLQISP---PLHQHLSMQQHQSLAMQQPLGSQLPMQVQTALHSPTMQQGFTLQ 469

  Fly   280 ---QHVDNTKAGYAKVMGEVTELMEENQRLETYLRALRQKLVAALGGISMPPLEP 331
               |.:.|..:..|:|   ||:.||       |:|:          |...||.:|
Mouse   470 PDYQTIINPTSTAAQV---VTQAME-------YVRS----------GCRNPPPQP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hmg-2	NP_611553.1	HMGB-UBF_HMG-box	76..141	CDD:238686	21/67 (31%)
Tox	NP_001364007.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..264		16/65 (25%)
		Nuclear localization signal. /evidence=ECO:0000255	237..256		5/26 (19%)
		NHP6B	<257..>360	CDD:227935	31/152 (20%)
		HMG-box	261..>310	CDD:238037	14/48 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810