Protein Alignment Magi and Hecw1

DIOPT Version :9

• Sequence 1: NP_001286661.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Sequence 2: XP_006516872.1
• Gene: Hecw1 / 94253
• MGIID: 2444115
• Length: 1605
• Species: Mus musculus
• Alignment Length: 569
• Identity: 107/569 - (18%)
• Similarity: 180/569 - (31%)
• Gaps: 186/569 - (32%)

  Fly    78 HPHPHPVAAATSFATFNGNSNL-NSSLANGSSRKFNCSR--------DNVDDGGDAGEMAAASQT 133
            |...|.:.:|...:|......| ..|....||.|...|.        .:::||...|      .|
Mouse   566 HTLLHSMPSAQRGSTTEEEDGLEEESTLKESSEKDGLSEVDTIAADPQSMEDGESDG------AT 624

  Fly   134 LSSAGTDVVGNGSGHGNGTVTGNGEKSGGLAPPG-GHHLRPPPPPALKKSASAVIGNSASREDVA 197
            |..|.:|..|   ||.:....|.|....|.|.|. |......|......|......:..|....:
Mouse   625 LCMAPSDCSG---GHFSSLSKGIGAGQDGEAHPSTGSESDSSPQQGADHSCEGCDASCCSPSCYS 686

  Fly   198 SLSGTSSL-------------NSQMSVHNQFISGLPSNGIGSNGVHGGAATGRGGPPNSILKGSK 249
            :...:||.             |::.:.|.:| |.:.|..|..               :::....:
Mouse   687 TSCYSSSCYSSSCYSSSCYNGNNRFASHTRF-SSVDSAKISE---------------STVFSSQE 735

  Fly   250 ENLLQNTYYNGETGDSSLGSECGVGDVQHQNHESHDDPGDGLGPLPPKWE----------TAYTE 304
            :...:|:.:  |:...|:           |:.|...:..:|.||    |:          ...||
Mouse   736 DEEEENSAF--ESVPDSV-----------QSPELDPESTNGAGP----WQDELAAPGGNAARSTE 783

  Fly   305 -------------RGELYFIDHNTGTSHWLDPRLSKYQKKSLEDCCEDELPYGWEKIEDSMYGMY 356
                         .||...:.::...|.....|...:...::    ::.||..||...||...::
Mouse   784 GLESPMAGPSNRREGECPILHNSQPISQLPSLRPEHHHYPTI----DEPLPPNWEARIDSHGRVF 844

  Fly   357 FIDHVNRRTQYENPVLEAKRRAAEQSQQQQQMQQQQQQMQEQRSKTPTALSETMPTEAAEA---- 417
            ::||:||.|.::.|.:........:|....||:|..::.|.        :..||.||.||.
Mouse   845 YVDHINRTTTWQRPSMAPTPDGMIRSGSVHQMEQLNRRYQN--------IQRTMATERAEEDSGN 901

  Fly   418 ------------------HEQEEDESPMKLPYKFTRNPAELQGQRINTTLLKSSRGLG------- 457
                              .|.|..:|.:.|..:.:.:|...|    ..|||..|..:.
Mouse   902 QNSEQIPDGGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQ----KVTLLLQSPAVKFITNPEF 962

  Fly   458 FTIVGSDGSAGGDVEEFLQIKTVVPNGPAWLDGQLQTGDVLVYVNDTCVL--------------G 508
            ||::.::.||                             ..|:.:.||:.              .
Mouse   963 FTVLHANYSA-----------------------------YRVFTSSTCLKHMILKVRRDARNFER 998

  Fly   509 YTHH-DMVNIFQSILPGERAALEVCRGYPLPFDPN------DPNTEVVT 550
            |.|: |:|| |.::....|  ||:.||:.:..|..      |.|:...|
Mouse   999 YQHNRDLVN-FINMFADTR--LELPRGWEIKTDHQGKSFFVDHNSRATT 1044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809	6/51 (12%)
		WW	342..372	CDD:238122	11/29 (38%)
		PDZ	443..534	CDD:214570	20/112 (18%)
		DegQ	<455..534	CDD:223343	16/100 (16%)
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
Hecw1	XP_006516872.1	HECW_N	66..185	CDD:374632
		C2_NEDL1-like	206..342	CDD:176073
		Neuromodulin	378..500	CDD:369001
		WW	829..858	CDD:366073	11/28 (39%)
		HECW1_helix	947..1013	CDD:375862	16/95 (17%)
		WW	1019..1050	CDD:197736	6/26 (23%)
		HECTc	1249..1603	CDD:238033

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900