Protein Alignment Magi and Ubr5

DIOPT Version :9

• Sequence 1: NP_001286661.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Sequence 2: XP_006520242.1
• Gene: Ubr5 / 70790
• MGIID: 1918040
• Length: 2800
• Species: Mus musculus
• Alignment Length: 1115
• Identity: 212/1115 - (19%)
• Similarity: 363/1115 - (32%)
• Gaps: 316/1115 - (28%)

  Fly     3 IITATTTSTAGGGAGVAA-----RGVATAKSPTDYLMLQQQQQQQQQQQQHF----------NSN 52
            ::||.|..:..|.:.|.|     ...:...|.:|    ....|....:|:.|          ||:
Mouse  1642 VVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSD----SSSSQSDDIEQETFMLDEPLERTTNSS 1702

  Fly    53 H---FYQQQQPQQLAPLNASHQHQHSHPHPHPHPVAAATSFATFNGNSNLNSSLANGSSRKFNCS 114
            |   ..|..:..|.|..|..||...|.........||:::...:...|||..|....:|.....:
Mouse  1703 HANGAAQAPRSMQWAVRNPQHQRAASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAA 1767

  Fly   115 RDNVDDGGDAGEMAAASQTLSSAGTDVVGNGSGHGNGTVTGNGEKSGGLAPPGGHHLRPPPPPAL 179
                     |.|.:.||..|:||      :........|........||.|...|.:....|.|:
Mouse  1768 ---------ALEASNASSYLTSA------SSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAV 1817

  Fly   180 KKSASAVIG--NSASREDVASLSGTSSLNSQMSVHNQFISGLPSNGIGSNGVHGGAATGRGGPPN 242
            |.:....:.  |....:.:.:.:...|:........::.|.|             |:.|..|.||
Mouse  1818 KLTYQDAVNLQNYVEEKLIPTWNWMVSVMDSTEAQLRYGSAL-------------ASAGDPGHPN 1869

  Fly   243 SILKGSKENLLQNTY----------YNGETGDSSLGSECGV----GDVQHQNH-----ESHDDPG 288
            ..|..|:.:..:...          ..|....:.|.:..|:    ||  ..|:     .||:|..
Mouse  1870 HPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGD--FLNYALSLMRSHNDEH 1932

  Fly   289 DGLGPLPPKWETAYTERGELYFIDHNTGTSHWLDPRLSKYQKKSLEDCCEDELPYGWEKIEDSMY 353
            ..:.|:                                      |:.|....:.|.::.:
Mouse  1933 SDVLPV--------------------------------------LDVCSLKHVAYVFQAL----- 1954

  Fly   354 GMYFIDHVNRRTQYENPVLEAK--RRAAEQSQQQQQMQQQQQQMQEQRSKTPTALSETMPTEAAE 416
             :|:|..:|::|..:.|.||.|  |...|.....:..:.:......|.:.......:::|.|..:
Mouse  1955 -IYWIKAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTSQSATLNDKDDDSLPAETGQ 2018

  Fly   417 AHE--QEEDE---------SPMKLP----YKFTRNPAELQGQRINTTLL-KSSRGLGFTIVGSDG 465
            .|.  :..|.         :|.::|    ......|..||.......|. :.|:||..:..|| |
Mouse  2019 NHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSAGS-G 2082

  Fly   466 SAGGDVEEFLQIKTVVPNGPAWL---------------DGQLQTGDVLVYVNDTCVLGYTHHDMV 515
            ....:|........|:|...::.               :|:.|:  :|....|:...|.:..|:.
Mouse  2083 KCIVEVTMDRNCLEVLPTKMSYAANLKNVMNMQNRQKKEGEEQS--LLAEEADSSKPGPSAPDVA 2145

  Fly   516 NIFQSILPGERAALEVCRGYPL-PFDPNDPNTEVVTTMAVDGRESDKQRRLNMDGNYNF-LDLSG 578
            ...:|.|..| ..|....|.|| .|.|......:|.:..:            :.|.:.. |:|.|
Mouse  2146 AQLKSSLLAE-IGLTESEGPPLTSFRPQCSFMGMVISHDM------------LLGRWRLSLELFG 2197

  Fly   579 EGAKKTSGSGSGFILMKKPEIYTFSIMKGSMGFGFTIADSACGQIVKKILDRNCCTQLME----- 638
            ....:..|:..|.||.:             :| ||.:.:|...:.::|:.::......:|
Mouse  2198 RVFMEDVGAEPGSILTE-------------LG-GFEVKESKFRREMEKLRNQQSRDLSLEVKVDR 2248

  Fly   639 -GDVLLEINGLNVRNKPHFYVVELLKECSQTTPTAV-KIQRTPPDPPANNTLAQLNQVGNVAKLR 701
             .|:|::.....:.|  ||.     :.|: |||.|| :::.|..|.|..
Mouse  2249 DRDLLIQQTMRQLNN--HFG-----RRCA-TTPMAVHRVKVTFKDEPGE---------------- 2289

  Fly   702 KNFVGSGLFRSKTPTADLYSTQVKEVLPMRPKTPLVDTRRSRVQIQSPN--------NEVDDEGD 758
                |||:.||       :.|.:.:......|.|.:|.      ||:.|        ..:.:.|:
Mouse  2290 ----GSGVARS-------FYTAIAQAFLSNEKLPNLDC------IQNANKGTHTSLMQRLRNRGE 2337

  Fly   759 GAAAAERKPLQLQTQGKSNSSLQELDDIPYMDPYPKISRLSERLAEVTLQGDANGGIYGMPPSMQ 823
            .....||:....::.|....|.::.|    .|...::| :..|......:|:         ||..
Mouse  2338 RDREREREREMRRSSGLRAGSRRDRD----RDFRRQLS-IDTRPFRPASEGN---------PSDD 2388

  Fly   824 PLPLPLAHHESCYCYDCQAQRYRPGYFVQAQQAAM-SGTTGQYSPLQTAHL-----QNERIQRRV 882
            |.||| ||.::.      .:|..|.  |||.|.|. |..||....|..|.|     ..:.::.||
Mouse  2389 PDPLP-AHRQAL------GERLYPR--VQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARV 2444

  Fly   883 NELLSDRRRVGFANLDPPQQMQHSPSWRNGA-------LLDVSEDADQCELTEVTLERQALGFGF 940
            :|.:               ::..:....|||       |||.||        :|...|:..|...
Mouse  2445 DEAM---------------ELIIAHGRENGADSILDLGLLDSSE--------KVQENRKRHGSSR 2486

  Fly   941 RIVG----GTEEGSQVTV--------GHIVPGGAADQDQRINTGDEILSIDGINVLNS------- 986
            .:|.    .|::|.....        |...|....:.:.|:|....|..|.|:.:|.:
Mouse  2487 SVVDMDLEDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITL 2551

  Fly   987 SHHKVVSLVG 996
            :.|.:..|:|
Mouse  2552 NRHVIKVLLG 2561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809	0/28 (0%)
		WW	342..372	CDD:238122	6/29 (21%)
		PDZ	443..534	CDD:214570	20/106 (19%)
		DegQ	<455..534	CDD:223343	18/93 (19%)
		PDZ_signaling	606..668	CDD:238492	12/67 (18%)
		PDZ	925..1011	CDD:214570	17/91 (19%)
		PDZ_signaling	1029..1110	CDD:238492
Ubr5	XP_006520242.1	CUE_UBR5	184..230	CDD:270606
		ZnF_UBR1	1177..1244	CDD:197698
		PolyA	2391..2454	CDD:197769	21/86 (24%)
		HECTc	2469..2797	CDD:214523	21/101 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900