Protein Alignment Magi and Arel1

DIOPT Version :9

• Sequence 1: NP_001286661.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Sequence 2: NP_001351118.1
• Gene: Arel1 / 68497
• MGIID: 1915747
• Length: 823
• Species: Mus musculus
• Alignment Length: 440
• Identity: 89/440 - (20%)
• Similarity: 144/440 - (32%)
• Gaps: 136/440 - (30%)

  Fly   682 PPANNTLAQLNQVGN--VAKLRKNFVGSGLFRSKTPTADLYSTQVKEVLPMRP------------ 732
            ||...:..:.|.:..  :..|.||..||..|:.|   .:.:..::::|...||
Mouse   409 PPVELSCKERNILAATFIRSLHKNIGGSETFQDK---VNFFQRELRQVHMKRPHSKVTLKVSRHA 470

  Fly   733 --KTPLVDTRRSRVQIQSPNNEV---DDEGDGAAAAERKPLQL----------QTQGKSNSSLQE 782
              ::.|..||...:...|.|.||   |:|........|:..:|          |...:...|.|.
Mouse   471 LLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTSQLFARFTDSNQA 535

  Fly   783 LDDIPYMDPYP--------KISRLSERLAEVTLQGDANGGIYGMPPSMQPLPLPLAHHESCYCYD 839
            |     :.|.|        |:...:.||....|...:.||.|.
Mouse   536 L-----VHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYK---------------------- 573

  Fly   840 CQAQRYRPGYFVQAQQAAMSGTTGQYSPLQT--AHLQNERIQRRVNELLSDRRRVGFANLDPPQQ 902
             |..|.|   |.::..|.:.|....|...:|  ......::...:|..:|:...| ||      :
Mouse   574 -QLVRAR---FTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELV-FA------E 627

  Fly   903 MQHSPSWRNGALLDVSEDADQCELTEVTLERQALGFGFRIVGGTEEGSQV--TVGHIVPG----- 960
            .:::.|.:...::::.....|   |.||...:.  |...::......|||  .|.|.:.|
Mouse   628 EKYNKSGQLDKIVELMTGGAQ---TPVTNANKI--FYLNLLAQYRLASQVKEEVEHFLKGLNELV 687

  Fly   961 -----GAADQDQ----RINTGDEILSIDGINVLNSSHHKVVSLVG------ESALR---GQVTMI 1007
                 ...|:::    ...|||       |||.:...|.||  ||      |..:|   ..|:.:
Mouse   688 PENLLAIFDENELELLMCGTGD-------INVSDFKAHAVV--VGGSWHFREKVMRWFWAVVSSL 743

  Fly  1008 LRRRRTPLLQQAPVSTQLRRYPYDVIVSRHENEGF-----GFVIISSSNH 1052
            .:.....|||....|:||            ...||     .|.||::..|
Mouse   744 TQEELARLLQFTTGSSQL------------PPGGFAALCPSFQIIAAPTH 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809
		WW	342..372	CDD:238122
		PDZ	443..534	CDD:214570
		DegQ	<455..534	CDD:223343
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570	25/110 (23%)
		PDZ_signaling	1029..1110	CDD:238492	6/29 (21%)
Arel1	NP_001351118.1	Filamin	56..154	CDD:395505
		Filamin	64..158
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..345
		HECTc	464..821	CDD:238033	76/382 (20%)
		Interaction with SOCS2. /evidence=ECO:0000250|UniProtKB:O15033	483..789		73/363 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900