DRSC/TRiP Functional Genomics Resources

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Protein Alignment Magi and Smurf2

DIOPT Version :9

Sequence 1:NP_001286661.1 Gene:Magi / 37403 FlyBaseID:FBgn0034590 Length:1202 Species:Drosophila melanogaster
Sequence 2:NP_079757.2 Gene:Smurf2 / 66313 MGIID:1913563 Length:748 Species:Mus musculus


Alignment Length:159 Identity:54/159 - (33%)
Similarity:76/159 - (47%) Gaps:34/159 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   254 QNTYYNGETGDSSLGSECG-----------VGDVQHQNHES----HDDPGDGLGPLPPKWETAYT 303
            :||...|..     |:.||           |...:|:|:.|    |..|     .||..:|...|
Mouse   208 ENTPITGTN-----GATCGHSSDPRLAERRVRSQRHRNYMSRTHLHTPP-----DLPEGYEQRTT 262

  Fly   304 ERGELYFIDHNTGTSHWLDPRLSKYQKKSLEDC-CED--ELPYGWEKIEDSMYG-MYFIDHVNRR 364
            ::|::||:...||.|.|.|||:    .:.|.:. ||:  .||.||| |.::..| :||:||.||.
Mouse   263 QQGQVYFLHTQTGVSTWHDPRV----PRDLSNINCEELGPLPPGWE-IRNTATGRVYFVDHNNRT 322

  Fly   365 TQYENPVLEAKRRAAEQSQQQQQMQQQQQ 393
            ||:.:|.|.|........|.|.:.|||||
Mouse   323 TQFTDPRLSANLHLVLNRQNQLKDQQQQQ 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MagiNP_001286661.1 WW 294..323 CDD:278809 11/28 (39%)
WW 342..372 CDD:238122 15/30 (50%)
PDZ 443..534 CDD:214570
DegQ <455..534 CDD:223343
PDZ_signaling 606..668 CDD:238492
PDZ 925..1011 CDD:214570
PDZ_signaling 1029..1110 CDD:238492
Smurf2NP_079757.2 C2_Smurf-like 13..137 CDD:176028
WW 159..188 CDD:278809
WW 252..283 CDD:197736 12/30 (40%)
WW 298..330 CDD:197736 16/32 (50%)
HECTc 393..745 CDD:238033
HECTc 420..745 CDD:214523
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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