Protein Alignment Magi and magi3b

DIOPT Version :10

• Sequence 1: NP_611551.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Sequence 2: XP_017212193.2
• Gene: magi3b / 564220
• ZFINID: ZDB-GENE-060503-301
• Length: 1406
• Species: Danio rerio
• Alignment Length: 931
• Identity: 283/931 - (30%)
• Similarity: 397/931 - (42%)
• Gaps: 291/931 - (31%)

  Fly   289 DGLGPLPPKWETAYTERGELYFIDHNTGTSHWLDPRLSKYQKKSLEDCCEDELPYGWEKIEDSMY 353
            |.|.|||..||.||||.|.:|||||||.::.||||||.| :.|..|.|.:.|||||||:|:|..|
Zfish   287 DSLEPLPYNWEMAYTETGMVYFIDHNTKSTTWLDPRLVK-KAKPPEKCEDGELPYGWEEIDDPQY 350

  Fly   354 GMYFIDHVNRRTQYENPVLEAKRRAAEQSQQQQQMQQQQQQMQEQRSKTPTALSETMPTEAAEAH 418
            |.|::||:|:|||:||||:||||:....:....|.||:........:.||
Zfish   351 GTYYVDHINQRTQFENPVVEAKRKLGLDTAVATQTQQRAAPPPGGAAGTP--------------- 400

  Fly   419 EQEEDESPMKLPYKFTRNPAELQGQRINTTLLKSSRGLGFTIVGSDGSAGGDVEEFLQIKTVVPN 483
                         .|||:|.:|:|:..:|.|.||.:|.||||:|.|.|     :||||:|.|:.:
Zfish   401 -------------GFTRDPTQLKGELYHTALRKSQQGFGFTIIGGDRS-----DEFLQVKNVLSD 447

  Fly   484 GPAWLDGQLQTGDVLVYVNDTCVLGYTHHDMVNIFQSILPGERAALEVCRGYPLPFD-------- 540
            |||..|.::.:|||:|.:|.|.|||.||.|:|::||.|...:...:.:||||.||.|
Zfish   448 GPAAQDNKMASGDVIVEINGTLVLGKTHADVVHMFQCIPINQYVDMVLCRGYSLPPDVDADSEDL 512

  Fly   541 ---PNDPNTEVVTTM-AVDGR----ESDKQRRLNMDGNYNFLDLSG----------EGAKKTSGS 587
               |..|..|:||.: .::|:    :.|.....:.:.:|...|.||          ..|.....:
Zfish   513 PPPPPPPTGEIVTAVPLINGQPLLVKGDALHGSSQELHYVTTDASGRPVVAALPASSAANDRPET 577

  Fly   588 GSGFILMKKPEIYTFSIMKGSMGFGFTIADSACGQIVKKILDRNCCTQLMEGDVLLEINGLNVRN 652
            |     |.:||:.:..|:||..||||.|||...||.||.|||...|..|::|||:.|||..||:.
Zfish   578 G-----MLQPELVSVPIVKGPGGFGFAIADCPLGQKVKMILDEQWCRGLLKGDVIKEINRQNVQT 637

  Fly   653 KPHFYVVELLKECSQTTPTAVKIQRTPPDPPANNTLAQLNQVGNVAKLRKNFVGSGLFRSKTPTA 717
            ..|..||::||                 |.|..:.:       |:..||
Zfish   638 LSHAQVVDILK-----------------DLPVGSEV-------NLLVLR---------------- 662

  Fly   718 DLYSTQVKEVLPMRPKTPLVDTRRSRVQIQSPNNEVDDEGDGAAAAERKPLQLQTQGKSNSSLQE 782
               ..|...|..:||:                                        |..::|.:.
Zfish   663 ---GGQTSPVKSLRPR----------------------------------------GGMSASTET 684

  Fly   783 LDDIPYMDPYPKISRLSERLAEVTLQGDANGGIYGMPPSMQPLPLPLAHHESCYCYDCQAQRYRP 847
            ||            |..:.:                      :|..|.:|
Zfish   685 LD------------RCHDMM----------------------VPQALTYH--------------- 700

  Fly   848 GYFVQAQQAAMSGTTGQYSPLQTAHLQNERIQRRVNELLSDRRRVGFANLDPPQQMQHS--PSWR 910
                       |.|....||.|.|.|...:                      |:.:..|  |.::
Zfish   701 -----------SNTLPCSSPKQDASLHYSK----------------------PKALTESIVPQYK 732

  Fly   911 NGALLDVSEDADQCELTEVTLERQALGFGFRIVGGTEEGSQVTVGHIVPGGAADQDQRINTGDEI 975
            .   |||....|           |..|||||::||......|.:|.|:|.|||:::.|:..|||:
Zfish   733 E---LDVFIKRD-----------QETGFGFRVLGGEGAEQPVYIGAIIPQGAAEKEGRLRAGDEL 783

  Fly   976 LSIDGINVLNSSHHKVVSLVGESALRGQVTMILRRR----------------------RTPLLQQ 1018
            :.||||.|...||.:|:.|:..:|..|||.:.:||:                      |.|.:|.
Zfish   784 IGIDGITVKGKSHKQVLDLMTNAARNGQVLLSVRRKVIFRDALEDVGSGALTLVNGSPRLPRIQV 848

  Fly  1019 APVSTQLRRYPYDVIVSRHENEGFGFVIISSSN------------HYYGSTIGKLIPGSPADRCG 1071
            ..|..|   ..:|:.:.|.:||||||||::|.:            |    .||::|.|||.||||
Zfish   849 PSVKDQ---ESFDITLHRRDNEGFGFVILTSKSKPPPGVCVSVIPH----KIGRIIEGSPTDRCG 906

  Fly  1072 ELKVGDRIVAVNRIEIAGMSHGDVVNLIKESGLHVRLTIGVPLKEGGPSPGGSSVGVSSNTPLQA 1136
            .|.|||||.|||...|..:||.|:|.|||::|..|.||: ||..|....|.|:|....|..|
Zfish   907 LLNVGDRISAVNSQSIVELSHNDIVQLIKDAGNSVTLTV-VPEDEYKGPPSGASSAKQSPAP--- 967

  Fly  1137 SPSLLKAQLSHQQQLPQQHLQ 1157
            ...:||:....:..|....::
Zfish   968 QHKILKSTQDERYNLDMDEIR 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_611551.1	WW	294..323	CDD:459800	18/28 (64%)
		WW	342..372	CDD:238122	19/29 (66%)
		PDZ1_MAGI-1_3-like	444..533	CDD:467213	38/88 (43%)
		PDZ2_MAGI-1_3-like	597..677	CDD:467214	34/79 (43%)
		PDZ3_MAGI-1_3-like	926..1010	CDD:467215	32/83 (39%)
		PDZ4_MAGI-1_3-like	1029..1111	CDD:467216	43/93 (46%)
magi3b	XP_017212193.2	None