DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Magi and Magix

DIOPT Version :9

Sequence 1:	NP_001286661.1	Gene:	Magi / 37403	FlyBaseID:	FBgn0034590	Length:	1202	Species:	Drosophila melanogaster
Sequence 2:	NP_061302.2	Gene:	Magix / 54634	MGIID:	1859644	Length:	324	Species:	Mus musculus

Alignment Length:	304	Identity:	71/304 - (23%)
Similarity:	120/304 - (39%)	Gaps:	65/304 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   944 GGTEEGS----------QVTVGHIVPGGAADQDQRINTGDEILSI---DGINVLNSSHHKVVSLV 995
            ||..:||          ::....:....|||....:......|.:   :|::.|:|:..:|.
Mouse    17 GGGLQGSRSPRARQLLERLDARPLAARAAADLTALVRKAGATLRLRHTEGVSGLDSADIEVT--- 78

  Fly   996 GESALRGQVTMILRR---RRTPLL----QQAPVSTQLRRYPYDV--IVSRHENE------GFGFV 1045
             :|.| ...|::..|   :|:..|    :..||:.....|...|  ...|...|      ||| :
Mouse    79 -DSRL-PHATLVKHRPQHQRSETLGTWTEPLPVTQNKASYALKVPQATGRFSVELTRGPAGFG-L 140

  Fly  1046 IISSSNHYYGS---TIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESGLHVR 1107
            .:|...:..|.   |:..|:...||.|||.|:.||.::.:|.....|::|..||..|:..|.|:.
Mouse   141 TLSGGRNVSGDAPLTVHGLLKDGPAQRCGRLQAGDLVLYINGQSTQGLTHAQVVERIRTGGPHLC 205

  Fly  1108 LTI-------GVPLKEGGP--------SPGGSSV-GVSSNTPLQASPSLLKAQLSHQQQLPQQHL 1156
            |.:       |..:||.|.        .|.||.| ..|:.:|:...|   |.:.|     |:...
Mouse   206 LVLQRPQDMDGSRIKEVGGHRKTDRSLDPRGSRVESRSTISPVHHRP---KTRTS-----PRPSP 262

  Fly  1157 QQAQLNHHHQHLEMP---MSMPVPG-HGSYLERPSNNISATLAL 1196
            :...:.|..:.:|.|   :...:|| .|.:|....:.:|..|.:
Mouse   263 EAVAIGHVVRAVEHPTEDLENRIPGTPGPWLVPSEDRLSRALGV 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809
		WW	342..372	CDD:238122
		PDZ	443..534	CDD:214570
		DegQ	<455..534	CDD:223343
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570	16/82 (20%)
		PDZ_signaling	1029..1110	CDD:238492	27/91 (30%)
Magix	NP_061302.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		4/8 (50%)
		PDZ	126..211	CDD:214570	26/85 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	216..263		14/54 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833682
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840