DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Magi and bag3

DIOPT Version :9

Sequence 1:	NP_001286661.1	Gene:	Magi / 37403	FlyBaseID:	FBgn0034590	Length:	1202	Species:	Drosophila melanogaster
Sequence 2:	NP_001003533.1	Gene:	bag3 / 445139	ZFINID:	ZDB-GENE-040801-40	Length:	459	Species:	Danio rerio

Alignment Length:	271	Identity:	58/271 - (21%)
Similarity:	91/271 - (33%)	Gaps:	92/271 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 PLPPKWETAY-TERGELYFIDHNTGTSHWLDPRLSKYQKKSLEDCCEDELPYGWEK-----IEDS 351
            ||||.||... .:.|..:|:|||..|:.|.|||....:..|.......|.|....|     :...
Zfish     6 PLPPGWEIKIDPQTGWPFFVDHNNRTTTWNDPRHDTKKIFSNGPSMSPETPQDMHKTFINEMRQP 70

  Fly   352 MYGMYFID----HVN---RRTQYEN----------------------PVLEAKRRAAEQSQQQ-- 385
            |....:|.    |.|   |..||.:                      |....:.|:..|:..:
Zfish    71 MLRQGYIPIPVCHENPEPRLQQYPSFSYIHPAVQQNLRTDGRTPSPTPAAHCRPRSPVQTPSEAC 135

  Fly   386 ------------QQMQQQQQQM----QEQRSKT---------------------PTALSETM-PT 412
                        .|.|...||:    |:.||..                     |:.||::. ||
Zfish   136 SSCSPTSHGPEGYQPQGTHQQISGLHQQPRSSNTGLRAGYIPIPVIHEGAGGVLPSQLSQSSHPT 200

  Fly   413 EAAEAHE-------QEEDESPMKLPYKFTRNP--AELQGQRINTTLLKSSRGLGFTIVGSDGSAG 468
            ......|       |....||:::|.: .::|  |::.|:|     .:..:.:|.|.:.|  ...
Zfish   201 REKIYREQVPIQIQQNRAASPIQVPLR-AQSPVMAQIMGER-----PQMQQHIGHTAIPS--KIE 257

  Fly   469 GDVEEFLQIKT 479
            ..|||.:::.|
Zfish   258 HPVEEIIRVPT 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809	12/29 (41%)
		WW	342..372	CDD:238122	10/63 (16%)
		PDZ	443..534	CDD:214570	8/37 (22%)
		DegQ	<455..534	CDD:223343	7/25 (28%)
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
bag3	NP_001003533.1	WW	6..38	CDD:197736	14/31 (45%)
bag3	NP_001003533.1	BAG	358..432	CDD:214591
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900