DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Magi and yki

DIOPT Version :9

Sequence 1:	NP_001286661.1	Gene:	Magi / 37403	FlyBaseID:	FBgn0034590	Length:	1202	Species:	Drosophila melanogaster
Sequence 2:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	60/269 - (22%)
Similarity:	109/269 - (40%)	Gaps:	69/269 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 PPPPALKKSASA------------VIGNSAS-------REDVASLS----GTSSLNSQMSVHNQF 215
            ||.|:..::.||            .|||.||       :..:|::.    ..|..:|::::|:..
  Fly   101 PPAPSHSRANSADSTYDAGSQSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSPQHSRLAIHHSR 165

  Fly   216 ISGLPSNGIGSNGVHGGAATGRGGPPNSILKGSK--------ENLLQNTYYNGETGDSSLG---- 268
            ....|::...:..|...:.......||:.....:        ||..|. :.:|....|::.
  Fly   166 ARSSPASLQQNYNVRARSDAAAANNPNANPSSQQQPAGPTFPENSAQE-FPSGAPASSAIDLDAM 229

  Fly   269 SECGVGDVQ------HQNHESHD--DP---GDGLGPLPPKWETAYTERGELYFIDHNTGTSHWLD 322
            :.|...|:.      |:...|:|  .|   ...||.|||.||.|.|..|::|:::|.|.::.|.|
  Fly   230 NTCMSQDIPMSMQTVHKKQRSYDVISPIQLNRQLGALPPGWEQAKTNDGQIYYLNHTTKSTQWED 294

  Fly   323 PRLSKYQKKSL--------EDCCE--------------DELPYGWEKIEDSMYGMYFIDHVNRRT 365
            ||:...|::.:        .|..:              ..||.|||:.......:|||:|::|.|
  Fly   295 PRIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIANNLGPLPDGWEQAVTESGDLYFINHIDRTT 359

  Fly   366 QYENPVLEA 374
            .:.:|.:::
  Fly   360 SWNDPRMQS 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809	12/28 (43%)
		WW	342..372	CDD:238122	11/29 (38%)
		PDZ	443..534	CDD:214570
		DegQ	<455..534	CDD:223343
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	31/108 (29%)
		WW	266..295	CDD:395320	12/28 (43%)
		WW	335..364	CDD:395320	11/28 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810