DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Magi and Magix

DIOPT Version :9

Sequence 1:	NP_001286661.1	Gene:	Magi / 37403	FlyBaseID:	FBgn0034590	Length:	1202	Species:	Drosophila melanogaster
Sequence 2:	NP_001014131.1	Gene:	Magix / 317379	RGDID:	1549729	Length:	326	Species:	Rattus norvegicus

Alignment Length:	157	Identity:	41/157 - (26%)
Similarity:	68/157 - (43%)	Gaps:	21/157 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   400 SKTPTA-LSETMPTEAAEAHEQEEDESPMKLPYKFTRNPAELQGQ------RINTTLLKSSRGLG 457
            |:.|.| |.|..|     .|::.:.:.|...|....:|.|....:      |.:..|::...|.|
  Rat    80 SRLPHATLVEHRP-----QHQRSDTQGPRMEPLPVIQNKASYASRLPQATGRFSVELVRGPAGFG 139

  Fly   458 FTIVGSDGSAGGDVEEFLQIKTVVPNGPAWLDGQLQTGDVLVYVNDTCVLGYTHHDMVNIFQSIL 522
            .|:.|. .:..|:|.  |.:..::.:|||...|.||.||:::|:|.....|.||...|...::
  Rat   140 LTLSGG-RNVSGNVP--LAVCGLLKDGPAQRCGHLQAGDLVLYINGQSTRGLTHAQAVEWIRT-- 199

  Fly   523 PGERAALEVCRGYPLPFDPNDPNTEVV 549
            .|.|..|.:.|    |.:.|...::.|
  Rat   200 GGPRLCLVLQR----PQEMNGSRSKEV 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809
		WW	342..372	CDD:238122
		PDZ	443..534	CDD:214570	26/96 (27%)
		DegQ	<455..534	CDD:223343	24/78 (31%)
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
Magix	NP_001014131.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		PDZ_signaling	127..209	CDD:238492	25/86 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	214..267		2/9 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337267
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284488at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840