Protein Alignment Magi and Arel1

DIOPT Version :9

• Sequence 1: NP_001286661.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Sequence 2: NP_001100214.1
• Gene: Arel1 / 299197
• RGDID: 1307597
• Length: 823
• Species: Rattus norvegicus
• Alignment Length: 605
• Identity: 119/605 - (19%)
• Similarity: 190/605 - (31%)
• Gaps: 240/605 - (39%)

  Fly   395 MQEQRSKTPTALSETMPTEAAEAHEQEEDESPMKL-----PYKFTRNPAELQ--GQRINTTLLKS 452
            |...:.:..|||.|......:|.|..|:.:.|.|:     |.:|:.....|:  ..|:.|  .:.
  Rat   319 MSSSQRRPSTALEEEEEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLYT--FRV 381

  Fly   453 SRGLGFTIVGSDGSAGGDVEEFLQIKTVVPNG---PAWL---DGQLQTGDVLVYVNDTCVLGYTH 511
            ..|..|:.:|.|     .|.:.|.:  ||.:|   |..|   :..:.....:..::.......|.
  Rat   382 CPGTKFSYLGPD-----PVHKLLTL--VVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETF 439

  Fly   512 HDMVNIFQSIL-------PGERAALEVCRGYPLP--------FDPND--PNTEVV---------- 549
            .|.||.||..|       |..:..|:|.|...|.        |..:|  .|.|||
  Rat   440 QDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWG 504

  Fly   550 ----------------TTMAVDGRESDKQR-------------RLNMDGNYNFLDLSGEGAKKTS 585
                            ||..:..|.||..:             ||.|   |.|
  Rat   505 GPRREWFELICKALFDTTSQLFTRFSDNNQALVHPNPNRPAHLRLKM---YEF------------ 554

  Fly   586 GSGSGFILMKKPEIYTFSIMKGSMGFGFTIADSACGQIVKKILDRNCCTQLMEGDVLLEINGLNV 650
               :|.::.|       .:.:.|:|       .|..|:|:....|:         .|.:|.||.:
  Rat   555 ---AGRLVGK-------CLYESSLG-------GAYKQLVRARFTRS---------FLAQIIGLRM 593

  Fly   651 RNK------PHFY---VVELLKECSQTTPTAVKIQRTPPDPPANNTLAQL---------NQVGNV 697
            ..|      |.||   |..:|                      ||.::::         |:.|.:
  Rat   594 HYKYFETDDPEFYKSKVCFIL----------------------NNDMSEMELVFAEEKYNKSGQL 636

  Fly   698 AKLRKNFVGSGLFRSKTPTADLYST-------------QVKEVLP--MRPKTPLVDTRRSRVQIQ 747
            .|:.:...|.    ::||..:...|             ||||.:.  ::....||
  Rat   637 DKIVELMTGG----AQTPVTNANKTFYLNLLAQYRLASQVKEEVEHFLKGLNELV---------- 687

  Fly   748 SPNN--EVDDEGDGAAAAERKPLQLQTQGKSNSSLQELDDIPYMDP-------------YPKISR 797
             |.|  .:.||.:         |:|...|..:.|:.:......:..             :..:|.
  Rat   688 -PENLLAIFDENE---------LELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSS 742

  Fly   798 LSE----RLAEVTLQGDAN---GGIYGMPPSMQPL------PLPLAHHESCY---C---YDCQAQ 843
            |::    ||.:.| .|.:.   ||...:.||.|.:      .||.||  :|:   |   ||...:
  Rat   743 LTQEELARLLQFT-TGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAH--TCFNQLCLPTYDSYEE 804

  Fly   844 RYRPGYFVQAQQAAMSGTTG 863
            .:|     ..|.|...|..|
  Rat   805 VHR-----MLQLAISEGCEG 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809
		WW	342..372	CDD:238122
		PDZ	443..534	CDD:214570	23/103 (22%)
		DegQ	<455..534	CDD:223343	21/91 (23%)
		PDZ_signaling	606..668	CDD:238492	16/70 (23%)
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
Arel1	NP_001100214.1	Filamin	56..154	CDD:395505
		HECTc	486..820	CDD:214523	80/429 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900