Protein Alignment Magi and Hecw1

DIOPT Version :9

• Sequence 1: NP_001286661.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Sequence 2: XP_017455974.1
• Gene: Hecw1 / 291209
• RGDID: 1561038
• Length: 1603
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 108/563 - (19%)
• Similarity: 177/563 - (31%)
• Gaps: 167/563 - (29%)

  Fly    70 HQHQHSHPHPHPHPVAAATSFATFNGNSNLNSSLANGSSRKFNCSR--------DNVDDGGDAGE 126
            |...||.|       :|.....|...::....|....||.|...|.        .:::||.:.|
  Rat   565 HTLLHSMP-------SAQRGSTTEEEDAMEEESTLKESSEKDGLSEVDTIAADPQSMEDGENNG- 621

  Fly   127 MAAASQTLSSAGTDVVGNGSGHGNGTVTGNGEKSGGLAPPGGHHLRPPPPPALKKSASAVIGNSA 191
                 .||..|.:|..|   ||     ..|..||.|....|..|    |....:..:|...|...
  Rat   622 -----ATLCMASSDCSG---GH-----FSNLSKSIGAGQDGEAH----PSTGSESDSSPQQGADH 669

  Fly   192 SREDV-ASLSGTSSLNSQMSVHNQFISGLPSNGIGSNGVHGGAATGRGGPPNSILKGSKENLLQN 255
            |.|.. ||....|..::..     :.|...|:...|:..:.|  ..|..............:.::
  Rat   670 SCEGCDASCCSPSCYSTSC-----YSSSCYSSSCYSSSCYNG--NNRFASHTRFSSVDSAKISES 727

  Fly   256 TYYNGETGDSSLGSECGVGDVQHQNHESHDDPGDGLGPLPPKWETAYTERGELYFIDHNTGTSHW 320
            |.::.:..:....|.........|:.|...:..:|.||    |:......|     .:...|:..
  Rat   728 TVFSSQEDEEEENSAFESVPDSVQSPELDPESTNGAGP----WQDELAAPG-----GNAARTTEG 783

  Fly   321 LDPRLSKYQKKSLEDC------------------------CEDELPYGWEKIEDSMYGMYFIDHV 361
            ||..::....:...||                        .::.||..||...||...::::|||
  Rat   784 LDSPMAGPSNRREGDCPMLHNSQPISQLPSLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHV 848

  Fly   362 NRRTQYENPVLEAKRRAAEQSQQQQQMQQQQQQMQEQRSKTPTALSETMPTEAAEA--------- 417
            ||.|.::.|.:........:|....||:|..::.|.        :..|:.||.:|.
  Rat   849 NRTTTWQRPSMAPTPDGMIRSGSVHQMEQLNRRYQN--------IQRTIATERSEEDSGNQSCEQ 905

  Fly   418 ------------HEQEEDESPMKLPYKFTRNPAELQGQRINTTLLKSSRGLG-------FTIVGS 463
                        .|.|..:|.:.|..:.:.:|...|    ..|||..|..:.       ||::.:
  Rat   906 IPDGGAGGGGSDSEAESSQSNLDLRREGSLSPVNSQ----KVTLLLQSPAVKFITNPEFFTVLHA 966

  Fly   464 DGSAGGDVEEFLQIKTVVPNGPAWLDGQLQTGDVLVYVNDTCVL--------------GYTHH-D 513
            :.||                             ..|:.:.||:.              .|.|: |
  Rat   967 NYSA-----------------------------YRVFTSSTCLKHMILKVRRDARNFERYQHNRD 1002

  Fly   514 MVNIFQSILPGERAALEVCRGYPLPFDPN------DPNTEVVT 550
            :|| |.::....|  ||:.||:.:..|..      |.|:...|
  Rat  1003 LVN-FINMFADTR--LELPRGWEIKTDHQGKSFFVDHNSRATT 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809	4/28 (14%)
		WW	342..372	CDD:238122	12/29 (41%)
		PDZ	443..534	CDD:214570	20/112 (18%)
		DegQ	<455..534	CDD:223343	16/100 (16%)
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
Hecw1	XP_017455974.1	HECW_N	66..185	CDD:293170
		C2_NEDL1-like	206..342	CDD:176073
		WW	827..857	CDD:197736	12/29 (41%)
		WW	1017..1048	CDD:197736	6/26 (23%)
		HECTc	1247..1601	CDD:238033
		HECTc	1271..1600	CDD:214523

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900