Protein Alignment Magi and HECW1

DIOPT Version :9

• Sequence 1: NP_001286661.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Sequence 2: XP_016867371.1
• Gene: HECW1 / 23072
• HGNCID: 22195
• Length: 1639
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 110/555 - (19%)
• Similarity: 185/555 - (33%)
• Gaps: 153/555 - (27%)

  Fly    76 HPHPHPHPVAAATSFATFNGNSNLNSSLANGSSRKFNCSRDNVDDGGDAGEMAAASQTLSSAGTD 140
            |...|..|.|...|.|.....:...|:|.:.|.:......|.|.....|.|........::.||.
Human   597 HTLLHSMPSAQGGSAAEEEDGAEEESTLKDSSEKDGLSEVDTVAADPSALEEDREEPEGATPGTA 661

  Fly   141 VVGNGSGH----GNG------TVTGNGEKSGGLAPPGGHH------LRPPPPPALKKSASAVIGN 189
            ..|:..||    .||      |....|.:|......||.|      .....|.....|..:....
Human   662 HPGHSGGHFPSLANGAAQDGDTHPSTGSESDSSPRQGGDHSCEGCDASCCSPSCYSSSCYSTSCY 726

  Fly   190 SASREDVASLSGTSSLNSQMSVHNQFISGLPSNGIGSNGVHGGAATGRGGPPNSILKGSKENLLQ 254
            |:|....:..|.:....::.:.|.:| |.:.|..|..               :::.....:...:
Human   727 SSSCYSASCYSPSCYNGNRFASHTRF-SSVDSAKISE---------------STVFSSQDDEEEE 775

  Fly   255 NTYYNGETGDSSLGSECGVGDVQHQNHESHDDPGDGLGPLPPKWE------TAYTER-------- 305
            |:.:  |:...|:           |:.|...:..:|.||    |:      :.:.||
Human   776 NSAF--ESVPDSM-----------QSPELDPESTNGAGP----WQDELAAPSGHVERSPEGLESP 823

  Fly   306 ---------GELYFIDHNTGTSHWLDPRLSKYQKKSLEDCCEDELPYGWEKIEDSMYGMYFIDHV 361
                     ||...:.::...|.....|...:...::    ::.||..||...||...::::|||
Human   824 VAGPSNRREGECPILHNSQPVSQLPSLRPEHHHYPTI----DEPLPPNWEARIDSHGRVFYVDHV 884

  Fly   362 NRRTQYENPVLEAKRRAAEQSQQQQQMQQQQQQMQEQRSKTPTALSE----TMPTEAAEA----- 417
            ||.|.::.|...|......:|...|||:|..::.|..:....|..||    :...|.|.|
Human   885 NRTTTWQRPTAAATPDGMRRSGSIQQMEQLNRRYQNIQRTIATERSEEDSGSQSCEQAPAGGGGG 949

  Fly   418 ----HEQEEDESPMKLPYKFTRNPAELQGQRINTTLLKSSRGLG-------FTIVGSDGSAGGDV 471
                .|.|..:|.:.|..:.:.:|  :..|:|  |||..|..:.       ||::.::.||
Human   950 GGSDSEAESSQSSLDLRREGSLSP--VNSQKI--TLLLQSPAVKFITNPEFFTVLHANYSA---- 1006

  Fly   472 EEFLQIKTVVPNGPAWLDGQLQTGDVLVYVNDTCVL--------------GYTHH-DMVNIFQSI 521
                                     ..|:.:.||:.              .|.|: |:|| |.::
Human  1007 -------------------------YRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVN-FINM 1045

  Fly   522 LPGERAALEVCRGYPLPFDPN------DPNTEVVT 550
            ....|  ||:.||:.:..|..      |.|:...|
Human  1046 FADTR--LELPRGWEIKTDQQGKSFFVDHNSRATT 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809	6/51 (12%)
		WW	342..372	CDD:238122	12/29 (41%)
		PDZ	443..534	CDD:214570	22/112 (20%)
		DegQ	<455..534	CDD:223343	16/100 (16%)
		PDZ_signaling	606..668	CDD:238492
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
HECW1	XP_016867371.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900