Protein Alignment Magi and Ube3a

DIOPT Version :9

• Sequence 1: NP_001286661.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Sequence 2: NP_001380595.1
• Gene: Ube3a / 22215
• MGIID: 105098
• Length: 870
• Species: Mus musculus
• Alignment Length: 561
• Identity: 111/561 - (19%)
• Similarity: 180/561 - (32%)
• Gaps: 171/561 - (30%)

  Fly   242 NSILKGSKENLLQNTYYNGETGDSSLGSECGVGDVQHQNHESHDDPGDGLGPLP----------- 295
            ::|:..||  .|:..||....|          |||. .||...||.    .|:|
Mouse   361 DAIVAASK--CLKMVYYANVVG----------GDVD-TNHNEEDDE----EPIPESSELTLQELL 408

  Fly   296 ---------PKWETAYTERGELYFIDHNTGTSHWLDPRLS--KYQKKSLEDCCEDELPYGWEKIE 349
                     |:.:...||.|        ..|.....|.:|  ::..:.|.|..|.:..|.:.|:|
Mouse   409 GDERRNKKGPRVDPLETELG--------VKTLDCRKPLISFEEFINEPLNDVLEMDKDYTFFKVE 465

  Fly   350 DS-----MYGMYFIDHV--NRRTQYENPV-LEAKRRAAEQSQQQQQMQQQQQQMQEQRSKTPTAL 406
            ..     |...:.::.|  |....|:|.: :.::||..    ....:.|.||.....|.|.
Mouse   466 TENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRIT----VLYSLVQGQQLNPYLRLKV---- 522

  Fly   407 SETMPTEAAEAHEQEEDESPMKLPYKFTRNPAELQGQRINTTLLKSSRGLGFTIVGSDG-SAGGD 470
                      ..:...|::.::|......|||:|:.|            |.....|..| ..||.
Mouse   523 ----------RRDHIIDDALVRLEMIAMENPADLKKQ------------LYVEFEGEQGVDEGGV 565

  Fly   471 VEEFLQIKTVVPNGP-------------AWL-------DGQLQ-TGDVL---VYVNDTCVLGYTH 511
            .:||.|:.......|             .|.       :||.. .|.||   :|.|  |:|. .|
Mouse   566 SKEFFQLVVEEIFNPDIGMFTYDEATKLFWFNPSSFETEGQFTLIGIVLGLAIYNN--CILD-VH 627

  Fly   512 HDMVNIFQSILPGERAALEVCRGYPLPFDPNDPNTEVVTTMAVDGRESDKQRRLNMDGNYNFLDL 576
            ..|| :::.::..:....::...:|:.:.......|...::..|...:.:..:.::.||....||
Mouse   628 FPMV-VYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGSVEDDMMITFQISQTDLFGNPMMYDL 691

  Fly   577 SGEGAK--KTSGSGSGFILMKKPEIYTFSIMKGSMGF--GFTIADS----------------ACG 621
            ...|.|  .|:.:...|:.:....|...|:.|....|  ||.:..:                .||
Mouse   692 KENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICG 756

  Fly   622 QIVKKILDRNCCTQLMEGDVLLEINGLNVRNK---------PHFYVVELLKECSQ-TTPTAVKIQ 676
                   .||...|.:|...  |.:|...|..         .|.:..|..:...| ||.|    .
Mouse   757 -------SRNLDFQALEETT--EYDGGYTRESVVIREFWEIVHSFTDEQKRLFLQFTTGT----D 808

  Fly   677 RTPPDPPANNTLAQLNQVGNVAKLRKNFVGSGLFRSKTPTA 717
            |.|              ||.:.||:.....:|....:.||:
Mouse   809 RAP--------------VGGLGKLKMIIAKNGPDTERLPTS 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809	6/48 (13%)
		WW	342..372	CDD:238122	8/37 (22%)
		PDZ	443..534	CDD:214570	23/115 (20%)
		DegQ	<455..534	CDD:223343	22/103 (21%)
		PDZ_signaling	606..668	CDD:238492	16/89 (18%)
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
Ube3a	NP_001380595.1	AZUL	27..81	CDD:406862
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..223
		HECTc	518..868	CDD:238033	72/375 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900