DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Magi and Gas7

DIOPT Version :9

Sequence 1:	NP_001286661.1	Gene:	Magi / 37403	FlyBaseID:	FBgn0034590	Length:	1202	Species:	Drosophila melanogaster
Sequence 2:	XP_006532265.1	Gene:	Gas7 / 14457	MGIID:	1202388	Length:	476	Species:	Mus musculus

Alignment Length:	168	Identity:	32/168 - (19%)
Similarity:	58/168 - (34%)	Gaps:	34/168 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   647 GLNVRNKPHFYVVELLKECSQTTPTAVKIQRTPPDPPANNTLAQLNQVGNVAKLRKNFVGSGLFR 711
            |::....||       :....||........||..||....::.....|:...|..:..|....:
Mouse   113 GISASPGPH-------RSSLPTTVNGYHASGTPAHPPETAHMSLRKSTGDSQNLGSSSPGRKQSK 170

  Fly   712 SKTPTADLYSTQVKEVLPMRPKTPLVDTRRSRVQIQSPN----------NEVDDEGDGAAAAERK 766
            ..|.|.:..:....:.:|.:             |:..|.          ::.|.:|:|..|....
Mouse   171 ENTITINCVTFPHPDTMPEQ-------------QLLKPTEWSYCDYFWADKKDPQGNGTVAGFEL 222

  Fly   767 PLQLQTQGKS-NSSLQEL--DDIPYMDPYPK-ISRLSE 800
            .||.|.:||. ...:.|.  :.|...:.|.| :::||:
Mouse   223 LLQKQLKGKQMQKEMSEFIRERIKIEEEYAKNLAKLSQ 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Magi	NP_001286661.1	WW	294..323	CDD:278809
		WW	342..372	CDD:238122
		PDZ	443..534	CDD:214570
		DegQ	<455..534	CDD:223343
		PDZ_signaling	606..668	CDD:238492	3/20 (15%)
		PDZ	925..1011	CDD:214570
		PDZ_signaling	1029..1110	CDD:238492
Gas7	XP_006532265.1	SH3_GAS7	5..57	CDD:212763
		WW_FCH_linker	109..201	CDD:374680	17/107 (16%)
		F-BAR_GAS7	214..446	CDD:153333	13/47 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900