Protein Alignment Tmtc3 and TSK

DIOPT Version :10

• Sequence 1: NP_477246.2
• Gene: Tmtc3 / 37401
• FlyBaseID: FBgn0020312
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_188503.2
• Gene: TSK / 821404
• AraportID: AT3G18730
• Length: 1311
• Species: Arabidopsis thaliana
• Alignment Length: 426
• Identity: 85/426 - (19%)
• Similarity: 151/426 - (35%)
• Gaps: 142/426 - (33%)

  Fly   511 QRNAKLYNNVGHALENEGKFEEALLYFQQAVRIQTDDIGAHINVGRTFNNLKRYAEAEQAYVQAK 575
            :..|:..||||..|:|.|::.:||.:|    ||..|     |:|               .|:..|
plant    23 REQARWANNVGDILKNHGEYVDALKWF----RIDYD-----ISV---------------KYLPGK 63

  Fly   576 ALFPQAKP-GVSYHARIAPNHLNVFINLANLIAKNQTRLEEADHLYRQAISMRSDYVQAYINRGD 639
            .|.|..:. |            .:::.|.|               :.:|:..:..::|......|
plant    64 DLLPTCQSLG------------EIYLRLEN---------------FEEALIYQKKHLQLAEEAND 101

  Fly   640 ILMKLNRTAQAQEVYEQALLYDNENADIYYNLGVVFLEQGKSQQAQVYFNKAIEL---------- 694
            .:.|.....|....|.:..|...::.:..             |.|:.||.||:||
plant   102 TVEKQRACTQLGRTYHEMFLKSEDDCEAI-------------QSAKKYFKKAMELAQILKEKPPP 153

  Fly   695 ------YPEHEQALLNSAILLQELGGEEARRVSRSRLYKVLENDDQNE------KVYFNLGMLAM 747
                  ..|:..|..|..:|..:|...||.|....:..::.:.::..|      :::.|||.:.|
plant   154 GESSGFLEEYINAHNNIGMLDLDLDNPEAARTILKKGLQICDEEEVREYDAARSRLHHNLGNVFM 218

  Fly   748 DESSFDEAEQFFKRAI-------HLKADFRSALFNLALLLADTKRPLDAV--------------- 790
            ...|:|||::..:..|       |::.:.:..: |||.|...|::.:||:
plant   219 ALRSWDEAKKHIEMDINICHKINHVQGEAKGYI-NLAELHNKTQKYIDALLCYGKASSLAKSMQD 282

  Fly   791 -PFLNQLIRHHPSHVKGLILLGDIYINHMKDLDEAEKCYRSILHYDPHNTQGLHNLCVVFVERKR 854
             ..|.:.|.|:...||..:.:       |::|.|.|...:. |..:..:.:|...      |||.
plant   283 ESALVEQIEHNTKIVKKSMKV-------MEELREEELMLKK-LSAEMTDAKGTSE------ERKS 333

  Fly   855 LAKAAAC-----------------LQYAQRLAPAED 873
            :.:..||                 |||::|.....|
plant   334 MLQVNACLGSLIDKSSMVFAWLKHLQYSKRKKKISD 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmtc3	NP_477246.2	TMTC_DUF1736	323..396	CDD:462468
		TPR	507..762	CDD:440225	55/273 (20%)
		TPR repeat	514..542	CDD:276809	11/27 (41%)
		TPR repeat	547..591	CDD:276809	7/44 (16%)
		TPR repeat	598..625	CDD:276809	3/26 (12%)
		TPR repeat	630..660	CDD:276809	5/29 (17%)
		LapB	634..896	CDD:442196	60/302 (20%)
		TPR repeat	665..693	CDD:276809	6/27 (22%)
		TPR repeat	737..764	CDD:276809	9/33 (27%)
		TPR repeat	803..834	CDD:276809	7/30 (23%)
		TPR repeat	839..867	CDD:276809	9/44 (20%)
TSK	NP_188503.2	TPR_12	24..98	CDD:315987	25/124 (20%)
		TPR repeat	26..58	CDD:276809	16/55 (29%)
		TPR repeat	68..94	CDD:276809	4/52 (8%)
		TPR	72..>293	CDD:440225	46/261 (18%)
		TPR repeat	105..143	CDD:276809	10/50 (20%)
		TPR repeat	164..192	CDD:276809	7/27 (26%)
		TPR repeat	206..236	CDD:276809	9/29 (31%)
		TPR repeat	247..273	CDD:276809	7/26 (27%)
		leucine-rich repeat	811..830	CDD:275380
		leucine-rich repeat	831..861	CDD:275380
		RNA1	<843..1076	CDD:444072
		leucine-rich repeat	867..887	CDD:275380
		leucine-rich repeat	900..925	CDD:275380
		leucine-rich repeat	926..953	CDD:275380
		leucine-rich repeat	954..984	CDD:275380
		leucine-rich repeat	985..1007	CDD:275380
		leucine-rich repeat	1008..1037	CDD:275380
		RNA1	<1031..>1166	CDD:444072
		leucine-rich repeat	1038..1059	CDD:275380
		leucine-rich repeat	1060..1094	CDD:275380
		leucine-rich repeat	1095..1123	CDD:275380
		leucine-rich repeat	1124..1151	CDD:275380