Protein Alignment Tmtc3 and spag1b

DIOPT Version :10

• Sequence 1: NP_477246.2
• Gene: Tmtc3 / 37401
• FlyBaseID: FBgn0020312
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: NP_001428503.1
• Gene: spag1b / 768178
• ZFINID: ZDB-GENE-061013-512
• Length: 607
• Species: Danio rerio
• Alignment Length: 229
• Identity: 46/229 - (20%)
• Similarity: 85/229 - (37%)
• Gaps: 36/229 - (15%)

  Fly   543 IQTDDI-GAHINVGRTFNNLKRYAEAEQAYVQAKALFPQAKPGVSYHARIAPNHLNVFINLANLI 606
            |||:|. ..|.::..|.:...........:.:|      ..||.:......|.|.::........
Zfish   392 IQTEDTPQGHTHIEDTSSGQMEVTPPGHIHNEA------TPPGHTPTNVTPPGHTHMMDEEHKET 450

  Fly   607 AKNQTRLEEADHLYRQAISMRSDYVQAYINRGDILMKLNRTAQAQEVYEQALLYDNENADIYYNL 671
            |:..|: :.::|...:...:|.|        |.:|.......:|.|.|.|:|..|......|.|.
Zfish   451 AEQHTQ-DNSEHTASELELLRHD--------GKVLFCSGCYEEAAEKYTQSLQLDTHTCAAYTNR 506

  Fly   672 GVVFLEQGKSQQAQVYFNKAIELYPEHEQALLNSAILLQELGGEEARRVSRSRLYKVLENDDQNE 736
            .:.:::..:..:||...:.|:::.|.:::|....|:..:   |.:.....||.|.:||..|
Zfish   507 ALCYIKLERFTEAQQDCDSALQIEPTNKKAFYRRALANK---GLKDYLSCRSDLQQVLRLD---- 564

  Fly   737 KVYFNLGMLAMDESSFDEAEQFFKRAIHLKADFR 770
                         :|..||::......||..|.|
Zfish   565 -------------ASVTEAQRLLMELTHLMEDRR 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmtc3	NP_477246.2	TMTC_DUF1736	323..396	CDD:462468
		TPR	507..762	CDD:440225	42/219 (19%)
		TPR repeat	514..542	CDD:276809
		TPR repeat	547..591	CDD:276809	6/44 (14%)
		TPR repeat	598..625	CDD:276809	3/26 (12%)
		TPR repeat	630..660	CDD:276809	7/29 (24%)
		LapB	634..896	CDD:442196	30/137 (22%)
		TPR repeat	665..693	CDD:276809	5/27 (19%)
		TPR repeat	737..764	CDD:276809	3/26 (12%)
		TPR repeat	803..834	CDD:276809
		TPR repeat	839..867	CDD:276809
spag1b	NP_001428503.1	None