Protein Alignment Tmtc3 and LOC4577322

DIOPT Version :10

• Sequence 1: NP_477246.2
• Gene: Tmtc3 / 37401
• FlyBaseID: FBgn0020312
• Length: 926
• Species: Drosophila melanogaster
• Sequence 2: XP_001238468.2
• Gene: LOC4577322 / 4577322
• VectorBaseID: AGAMI1_013727
• Length: 420
• Species: Anopheles gambiae
• Alignment Length: 226
• Identity: 48/226 - (21%)
• Similarity: 73/226 - (32%)
• Gaps: 73/226 - (32%)

  Fly   556 RTFNNLKRYA--EAEQAYVQAKALFPQAKPGVSY-HARIAPNHLN---------VFINLANLIAK 608
            |||...||.:  :|||.:...:|   .|:..|.: ...:.|:..|         .|....|.:|
Mosquito   241 RTFVTPKRESMEQAEQEWTLKQA---AARRAVGFADDDLRPDERNPEWLKQRGDTFFQQRNFLA- 301

  Fly   609 NQTRLEEADHLYRQAISMRSDYVQAYINRGDILMKLNRTAQAQEVYEQAL------LYDNENADI 667
                   |...|...|.:..||...::||....:.|....:..|....||      :..|..|.:
Mosquito   302 -------AISAYSAGIRLTKDYYALFLNRSAAHLALENYQRCAEDCSTALELLQPPVEANRRARV 359

  Fly   668 ---------YYNLGVVFLEQGKSQQAQVYFNKAIELYPEHEQALLNSAILLQELGGEEARRVSRS 723
                     ...||  ||:||..:..     .|..|.|:                 |.:.|:...
Mosquito   360 ACLARRAAALVKLG--FLQQGYEEMI-----AASRLDPD-----------------EASLRLEVD 400

  Fly   724 RLYKVLENDDQNEKVYFNLGMLAMDESSFDE 754
            ||.:.:|.:.:|.           .||..||
Mosquito   401 RLRRCIEEERKNR-----------SESESDE 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmtc3	NP_477246.2	TMTC_DUF1736	323..396	CDD:462468
		TPR	507..762	CDD:440225	48/226 (21%)
		TPR repeat	514..542	CDD:276809
		TPR repeat	547..591	CDD:276809	11/37 (30%)
		TPR repeat	598..625	CDD:276809	5/26 (19%)
		TPR repeat	630..660	CDD:276809	7/35 (20%)
		LapB	634..896	CDD:442196	27/136 (20%)
		TPR repeat	665..693	CDD:276809	8/36 (22%)
		TPR repeat	737..764	CDD:276809	4/18 (22%)
		TPR repeat	803..834	CDD:276809
		TPR repeat	839..867	CDD:276809
LOC4577322	XP_001238468.2	None