DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tmtc3 and CG14921

DIOPT Version :9

Sequence 1:	NP_477246.2	Gene:	Tmtc3 / 37401	FlyBaseID:	FBgn0020312	Length:	926	Species:	Drosophila melanogaster
Sequence 2:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster

Alignment Length:	136	Identity:	33/136 - (24%)
Similarity:	59/136 - (43%)	Gaps:	21/136 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   529 KFEEALLYFQQAVRIQTDDIGAHINVGRTFNNLKRYAEAEQAYV-QAKALFPQAKPGVSYHARIA 592
            ||....::|::.:..:.|::.:..   |.|.|     ||....| :.|.|:|:....:...|.:.
  Fly    35 KFNNPPIFFERHLAQEIDEMASFC---RIFKN-----EARIVLVKKEKGLWPEMFQKLDKEALMQ 91

  Fly   593 PNHLNVFINLANLIA-KNQTRLEEADHLYRQAISMRSDYVQAYINRGDILMKLNRTAQAQE-VYE 655
            ..     :.:|:||. :|:.|.|:|...|.   :.|...:|..|.|...:.:  |..|.|| ...
  Fly    92 KR-----LEIADLIVERNKKRDEKALERYD---NKRRAEIQKEIQRETDMRE--RVKQFQENSVR 146

  Fly   656 QALLYD 661
            :||:.|
  Fly   147 EALVVD 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tmtc3	NP_477246.2	DUF1736	323..396	CDD:369859
		PEP_TPR_lipo	<513..871	CDD:274350	33/136 (24%)
		TPR repeat	514..542	CDD:276809	3/12 (25%)
		TPR repeat	547..591	CDD:276809	10/44 (23%)
		TPR repeat	598..625	CDD:276809	8/27 (30%)
		TPR repeat	630..660	CDD:276809	9/30 (30%)
		TPR repeat	665..693	CDD:276809
		TPR repeat	737..764	CDD:276809
		TPR repeat	803..834	CDD:276809
		TPR repeat	839..867	CDD:276809
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	13/53 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900