DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tmtc3 and tomm34

DIOPT Version :9

Sequence 1:NP_477246.2 Gene:Tmtc3 / 37401 FlyBaseID:FBgn0020312 Length:926 Species:Drosophila melanogaster
Sequence 2:NP_955932.2 Gene:tomm34 / 323361 ZFINID:ZDB-GENE-030131-2081 Length:305 Species:Danio rerio


Alignment Length:320 Identity:63/320 - (19%)
Similarity:106/320 - (33%) Gaps:91/320 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   463 QRRGSLSWQRFSQA----------ALAILLLTHALKTHQRNLDWRTEYSLFMSGVHVNQRNAKLY 517
            |:|.:.||....||          ..|:.|.:.|::..:::...:||    ..|:        ||
Zfish     3 QKRRTQSWTDLKQAGNECFKAGQYGEAVTLYSQAIQQLEKSGQKKTE----DLGI--------LY 55

  Fly   518 NNVGHALENEGKFEEALLYFQQAVRIQTDDIGAHINVGRTFNNLKRYAEAEQAYVQAKAL----- 577
            :|...:...:|...|.:.....::.:......|.:.....|..|:||   .||||..|.:     
Zfish    56 SNRAASYLKDGNCNECIKDCTASLDLVPFGFKALLRRAAAFEALERY---RQAYVDYKTVLQIDW 117

  Fly   578 -FPQAKPGV-------------SYHARIAP----------------------NHLNVFINL---- 602
             .|.|..||             |:..::.|                      ...||..:.    
Zfish   118 NIPAAHDGVNRMTKALTEMDGPSWREKLPPIPTVPMSVKEKLGQAASPASSSQQNNVIDDKKKAP 182

  Fly   603 -ANLIAKNQTRLEEADHL------------YRQAISMRSDYVQAYINRGDILMKLNRTAQAQEVY 654
             .:.:.|.:|..||.:.|            |.|:::.....|..|.||....:.|.....|....
Zfish   183 GPDAVKKGRTLKEEGNALVKKGEHKKAMEKYTQSLAQDPTEVTTYTNRALCYLALKMYKDAIRDC 247

  Fly   655 EQALLYDNENADIYYNLGVVFLEQGKSQQAQVYFNKAIELYPEHEQALLNSAI--LLQEL 712
            |:||..|:.|....|.....:.|....:......|..:::.|.      |:|:  ||||:
Zfish   248 EEALRLDSANIKALYRRAQAYKELKNKKSCIEDLNSVLKIDPN------NTAVQKLLQEV 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tmtc3NP_477246.2 DUF1736 323..396 CDD:369859
PEP_TPR_lipo <513..871 CDD:274350 51/260 (20%)
TPR repeat 514..542 CDD:276809 5/27 (19%)
TPR repeat 547..591 CDD:276809 15/62 (24%)
TPR repeat 598..625 CDD:276809 8/43 (19%)
TPR repeat 630..660 CDD:276809 9/29 (31%)
TPR repeat 665..693 CDD:276809 3/27 (11%)
TPR repeat 737..764 CDD:276809
TPR repeat 803..834 CDD:276809
TPR repeat 839..867 CDD:276809
tomm34NP_955932.2 TPR_11 13..83 CDD:290150 13/81 (16%)
TPR repeat 13..38 CDD:276809 5/24 (21%)
TPR repeat 43..81 CDD:276809 8/49 (16%)
TPR_11 54..116 CDD:290150 15/64 (23%)
TPR repeat 86..114 CDD:276809 10/30 (33%)
TPR_11 191..254 CDD:290150 15/62 (24%)
TPR repeat 191..218 CDD:276809 6/26 (23%)
TPR repeat 223..253 CDD:276809 9/29 (31%)
TPR_11 226..289 CDD:290150 13/62 (21%)
TPR 226..257 CDD:197478 9/30 (30%)
TPR_1 258..291 CDD:278916 4/38 (11%)
TPR repeat 258..286 CDD:276809 3/27 (11%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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