DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tmtc3 and Ifit3

DIOPT Version :9

Sequence 1:NP_477246.2 Gene:Tmtc3 / 37401 FlyBaseID:FBgn0020312 Length:926 Species:Drosophila melanogaster
Sequence 2:NP_001007695.1 Gene:Ifit3 / 309526 RGDID:1359681 Length:411 Species:Rattus norvegicus


Alignment Length:299 Identity:56/299 - (18%)
Similarity:120/299 - (40%) Gaps:79/299 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   602 LANLIAKNQTRLE---EADHLYRQAISMRSDYVQAYINRGD---ILMKLNRTAQAQEVYEQ---- 656
            :.:|..:|:..||   :|:.|.:...|.|:: ::..:..|:   |..::.:.::||...::    
  Rat    60 IKHLDGENEAALECLGQAEDLRKSERSDRAE-IKCLVTWGNYAWIYYRIGQLSEAQAYADKVRQV 123

  Fly   657 ----ALLYDNENADIYYNLGVVFLEQGKSQQAQVYFNKAIELYPEHEQALLNSAILLQELGGEEA 717
                |..|..|..::....|...|:.|::::|::.|.||:|..||..:.....||.:..|..:..
  Rat   124 CQKFANPYSMECPELDCEEGWTRLKCGRNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQEKPE 188

  Fly   718 RRVSRSRLYKVLENDDQN--EKVYFNLGMLAMDE------------------------------- 749
            ::.|...|.:.:|.:.||  |||...|.:..|.|                               
  Rat   189 KQFSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRK 253

  Fly   750 -SSFDEAEQFFKRAIHLKADFRSALFNLALL----------------LADTKRPLD-----AVPF 792
             .:.|.|.:|..:|:...|: .|.|::|.:.                .::.::.::     .:.:
  Rat   254 KGNLDRAIEFLGKALRSTAN-NSPLYSLVMCRYREKLKQLQNTGEADKSERRQTMEELRRLTMEY 317

  Fly   793 LNQLIRHHPSHVKGLILLGDIYINHMKDLDEAEKCYRSI 831
            :|:.::..||.:..        .:.:.|..|.||||:.:
  Rat   318 MNKALQRRPSPLNS--------YSDLIDFPEVEKCYQMV 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tmtc3NP_477246.2 DUF1736 323..396 CDD:369859
PEP_TPR_lipo <513..871 CDD:274350 56/299 (19%)
TPR repeat 514..542 CDD:276809
TPR repeat 547..591 CDD:276809
TPR repeat 598..625 CDD:276809 6/25 (24%)
TPR repeat 630..660 CDD:276809 5/40 (13%)
TPR repeat 665..693 CDD:276809 7/27 (26%)
TPR repeat 737..764 CDD:276809 9/58 (16%)
TPR repeat 803..834 CDD:276809 6/29 (21%)
TPR repeat 839..867 CDD:276809
Ifit3NP_001007695.1 TPR_12 51..126 CDD:290160 12/66 (18%)
TPR repeat 51..79 CDD:276809 5/18 (28%)
TPR repeat 93..123 CDD:276809 4/29 (14%)
TPR_12 94..164 CDD:290160 14/69 (20%)
TPR repeat 136..164 CDD:276809 7/27 (26%)
TPR repeat 206..236 CDD:276809 7/29 (24%)
TPR_19 217..281 CDD:291240 9/64 (14%)
TPR repeat 241..269 CDD:276809 4/27 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.