DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ktub and TLP5

DIOPT Version :9

Sequence 1:	NP_611549.2	Gene:	ktub / 37400	FlyBaseID:	FBgn0015721	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_564485.1	Gene:	TLP5 / 840948	AraportID:	AT1G43640	Length:	429	Species:	Arabidopsis thaliana

Alignment Length:	453	Identity:	126/453 - (27%)
Similarity:	183/453 - (40%)	Gaps:	134/453 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 DLIEEISSHELEDEESSPVTVIEQHQQSASHSA-----------NSTQSQKPRARQHSFSDNLDE 169
            |.:...|....:...|:..|    ||:|.||..           |:..:..|.|........|||
plant    12 DTVGSFSRRSFDVRVSNGTT----HQRSKSHGVEAHIEDLIVIKNTRWANLPAALLRDVMKKLDE 72

  Fly   170 DDYT---NRNVAGAAPVRPA------GMASSPYKDATLDGSSNGTGNGTGGESEGDVIGNIDQFV 225
            .:.|   .:.|...|.|...      .:..||                   |..|.:...:.  :
plant    73 SESTWPARKQVVACAGVCKTWRLMCKDIVKSP-------------------EFSGKLTFPVS--L 116

  Fly   226 MQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLER------DYGKKIFLLGGRKRKKSKTSNYIV 284
            .||.|:..:.:|.|.||:..|      .|:|:|..      :.||  |||..::.:::..:.|::
plant   117 KQPGPRDGIIQCYIKRDKSNM------TYHLYLSLSPAILVESGK--FLLSAKRSRRATYTEYVI 173

  Fly   285 SCDPTDLSRNADGFCGKLRSNVFGTSFTVFD--------------------NGNKESTESP--RL 327
            |.|..::||::..:.|||:||..||.|.|:|                    |..|.|.:.|  ..
plant   174 SMDADNISRSSSTYIGKLKSNFLGTKFIVYDTAPAYNSSQILSPPNRSRSFNSKKVSPKVPSGSY 238

  Fly   328 DLAVIIYDTNILGFKGPRNMTVIL---------PGMTEDDQ------------RVKISSADPKQQ 371
            ::|.:.|:.|:||.:|||.|..|:         ||.|...|            |...||......
plant   239 NIAQVTYELNLLGTRGPRRMNCIMHSIPSLALEPGGTVPSQPEFLQRSLDESFRSIGSSKIVNHS 303

  Fly   372 GILDLWKMKNMDNIVE---LHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLV------------ 421
            |  |..:.|..:..|.   |..|.|.|....:.:.|||.||||.||||||||:
plant   304 G--DFTRPKEEEGKVRPLVLKTKPPRWLQPLRCWCLNFKGRVTVASVKNFQLMSAATVQPGSGSD 366

  Fly   422 ---------------HDSDPEYIVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIACE 469
                           ..|:.:.|::.||:..:|:|||||||||.|.|||||:||:||.|:|||
plant   367 GGALATRPSLSPQQPEQSNHDKIILHFGKVGKDMFTMDYRYPLSAFQAFAISLSTFDTKLACE 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ktub	NP_611549.2	Tub	228..462	CDD:279506	96/312 (31%)
TLP5	NP_564485.1	F-box	54..106	CDD:279040	11/70 (16%)
TLP5	NP_564485.1	Tub	119..422	CDD:279506	96/312 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	147	1.000	Domainoid score	I1448
eggNOG	1	0.900	-	-		E1_KOG2502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1660
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	1	1.000	-	-		FOG0000431
OrthoInspector	1	1.000	-	-		otm2426
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X288
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.970