DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ktub and TLP3

DIOPT Version :9

Sequence 1:	NP_611549.2	Gene:	ktub / 37400	FlyBaseID:	FBgn0015721	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001189775.1	Gene:	TLP3 / 819402	AraportID:	AT2G47900	Length:	407	Species:	Arabidopsis thaliana

Alignment Length:	305	Identity:	110/305 - (36%)
Similarity:	158/305 - (51%)	Gaps:	74/305 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 QPAPQGVLYKCRITRDRKGMDRGLFPIYYLHL-------ERDYGKKIFLLGGRKRKKSKTSNYIV 284
            ||.|:|.|.:|.|.|:|...      .|||:|       ..|.||  |||..::.::...::||:
plant   115 QPGPRGSLVQCYIMRNRSNQ------TYYLYLGLNQAAASNDDGK--FLLAAKRFRRPTCTDYII 171

  Fly   285 SCDPTDLSRNADGFCGKLRSNVFGTSFTVFD----NGNKESTE------------SPRL-----D 328
            |.:..|:||.::.:.||||||..||.|||:|    |...:.|.            |||:     .
plant   172 SLNCDDVSRGSNTYIGKLRSNFLGTKFTVYDAQPTNPGTQVTRTRSSRLLSLKQVSPRIPSGNYP 236

  Fly   329 LAVIIYDTNILGFKGPRNMTVIL---------PGMTEDDQRVKISS---ADPKQQGILDLWKMKN 381
            :|.|.|:.|:||.:|||.|..::         ||.|...|...:.|   :.|.    ...::.|:
plant   237 VAHISYELNVLGSRGPRRMQCVMDAIPASAVEPGGTAPTQTELVHSNLDSFPS----FSFFRSKS 297

  Fly   382 M---------------DNIVELHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLV-----HDSDP 426
            :               :.::.|.||.|.|:::.|.:.|||:||||.|||||||||     ..:.|
plant   298 IRAESLPSGPSSAAQKEGLLVLKNKAPRWHEQLQCWCLNFNGRVTVASVKNFQLVAAPENGPAGP 362

  Fly   427 EY--IVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIACE 469
            |:  :::|||:..:|||||||:||:.|.|||.|.|||||.|||||
plant   363 EHENVILQFGKVGKDVFTMDYQYPISAFQAFTICLSSFDTKIACE 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ktub	NP_611549.2	Tub	228..462	CDD:279506	101/295 (34%)
TLP3	NP_001189775.1	F-box	50..95	CDD:395521
TLP3	NP_001189775.1	Tub	115..402	CDD:395929	104/298 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	147	1.000	Domainoid score	I1448
eggNOG	1	0.900	-	-		E1_KOG2502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1660
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1445357at2759
OrthoFinder	1	1.000	-	-		FOG0000431
OrthoInspector	1	1.000	-	-		otm2426
orthoMCL	1	0.900	-	-		OOG6_101683
Panther	1	1.100	-	-	O	PTHR16517
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X288
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.870